Promotion of G alpha i3 subunit down-regulation by GIPN, a putative E3 ubiquitin ligase that interacts with RGS-GAIP (Q24680028)

1

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Luc De Vries

2

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Timo Meerloo

3

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Marilyn Gist Farquhar

Proceedings of the National Academy of Sciences of the United States of America

4

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language of work or name

English

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publication date

8 July 2003

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published in

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volume

100

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issue

14

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page(s)

8270-5

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cites work

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Galpha i3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer of green fluorescent protein fusion proteins

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Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits

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Clathrin-coated vesicles bearing GAIP possess GTPase-activating protein activity in vitro

7 April 2017

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GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP

7 April 2017

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RGS-GAIP, a GTPase-activating protein for Galphai heterotrimeric G proteins, is located on clathrin-coated vesicles

7 April 2017

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GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits

7 April 2017

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GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain

7 April 2017

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Ubiquitylation of the transducin betagamma subunit complex. Regulation by phosducin

7 April 2017

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The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2

7 April 2017

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HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

7 April 2017

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Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

7 April 2017

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Themes and variations on ubiquitylation

7 April 2017

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RING finger proteins: mediators of ubiquitin ligase activity

7 April 2017

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The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

7 April 2017

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GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

7 April 2017

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The regulator of G protein signaling family

7 April 2017

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RGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily

7 April 2017

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Using CLUSTAL for multiple sequence alignments

7 April 2017

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Impairment of the ubiquitin-proteasome system by protein aggregation

7 April 2017

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Direct identification of a G protein ubiquitination site by mass spectrometry

7 April 2017

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Screening for interacting partners for G alpha i3 and RGS-GAIP using the two-hybrid system

28 September 2017

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RGSZ1 and Ret RGS: two of several splice variants from the gene RGS20.

28 September 2017

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Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

Proteasome involvement in agonist-induced down-regulation of mu and delta opioid receptors

28 September 2017

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Degradation of heterotrimeric Galpha(o) subunits via the proteosome pathway is induced by the hsp90-specific compound geldanamycin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

Divergence of RGS proteins: evidence for the existence of six mammalian RGS subfamilies

28 September 2017

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Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.

28 September 2017

1 reference

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Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

The core domain of a new retina specific RGS protein stimulates the GTPase activity of transducin in vitro.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

Applications of network BLAST server

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

RGS4 is arginylated and degraded by the N-end rule pathway in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

A function for monoubiquitination in the internalization of a G protein-coupled receptor

30 May 2018

1 reference

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Degradation of G alpha by the N-end rule pathway

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

Heterogeneous localization of G protein alpha-subunits in rat kidney

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

Localization and polar distribution of several G-protein subunits along nephron segments

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166218

The U box is a modified RING finger — a common domain in ubiquitination

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1432965100

Pheromone-dependent ubiquitination of the mitogen-activated protein kinase kinase Ste7.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1432965100

Agonist-mediated downregulation of G alpha i via the alpha 2-adrenergic receptor is targeted by receptor-Gi interaction and is independent of receptor signaling and regulation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12826607

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Degradation of the G protein-coupled receptor kinase 2 by the proteasome pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12826607

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ubiquitin and the control of protein fate in the secretory and endocytic pathways

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12826607