Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function (Q24682460)

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T Büsgen

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A Brychzy

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S Jentsch

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A Pause

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

11 May 1999

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published in

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volume

96

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issue

10

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page(s)

5510-5

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cites work

A new NEDD8-ligating system for cullin-4A

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

7 April 2017

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Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2

7 April 2017

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Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

7 April 2017

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Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein

7 April 2017

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The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

7 April 2017

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A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

7 April 2017

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A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

7 April 2017

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cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

7 April 2017

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Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

7 April 2017

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Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II

7 April 2017

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Inhibition of transcription elongation by the VHL tumor suppressor protein

7 April 2017

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Conjugates of ubiquitin cross-reactive protein distribute in a cytoskeletal pattern

7 April 2017

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Protein breakdown. Ubiquitous déjà vu.

7 April 2017

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Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1.

7 April 2017

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Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

7 April 2017

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A novel protein modification pathway related to the ubiquitin system

7 April 2017

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Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

7 April 2017

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Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

7 April 2017

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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

7 April 2017

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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

7 April 2017

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Ubiquitin-dependent protein degradation

7 April 2017

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Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins

7 April 2017

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

7 April 2017

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SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

7 April 2017

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Identification of a set of genes with developmentally down-regulated expression in the mouse brain

7 April 2017

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7 April 2017

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Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway

7 April 2017

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Identification of the von Hippel-Lindau disease tumor suppressor gene

7 April 2017

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The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix

7 April 2017

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Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21890

The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal

28 September 2017

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Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2.

28 September 2017

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The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity

28 September 2017

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The molecular basis of von Hippel-Lindau disease

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21890

Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21890

Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

28 September 2017

1 reference

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Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma

28 September 2017

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Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin

28 September 2017

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The interferon-inducible 15-kDa ubiquitin homolog conjugates to intracellular proteins

28 September 2017

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Tumour suppression by the human von Hippel-Lindau gene product

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21890

Proteolysis and the G1-S transition: the SCF connection

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21890

SUMO-1: wrestling with a new ubiquitin-related modifier.

30 May 2018

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SUMO-1: Ubiquitin gains weight

30 May 2018

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The ubiquitin-related protein RUB1 and auxin response in Arabidopsis.

21 January 2018

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The Elongin BC complex and the von Hippel-Lindau tumor suppressor protein.

21 January 2018

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28 November 2018

An Asian Grande Coupure

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https://api.crossref.org/works/10.1073%2FPNAS.96.10.5510

G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.96.10.5510

von Hippel-Lindau disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.10.5510

Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10318914

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

There's the rub: a novel ubiquitin-like modification linked to cell cycle regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10318914