Proteolysis and the G1-S transition: the SCF connection (Q41732732)

8 October 2017

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title

Proteolysis and the G1-S transition: the SCF connection (English)

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8 October 2017

ubiquitin ligase complex

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Gene Ontology release 2020-05-02

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W Krek

1

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8 October 2017

1 February 1998

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Current Opinion in Genetics & Development

8 October 2017

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8 October 2017

8

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8 October 2017

1

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8 October 2017

36-42

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Phosphorylation and proteolysis: partners in the regulation of cell division in budding yeast

8 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

How proteolysis drives the cell cycle

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The ubiquitin-proteasome proteolytic pathway

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Ubiquitin-dependent protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

G1 phase progression: cycling on cue

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Control of the yeast cell cycle by the Cdc28 protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Principles of CDK regulation

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Linkage of replication to start by the Cdk inhibitor Sic1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

p34Cdc28-mediated control of Cln3 cyclin degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

G2 cyclins are required for the degradation of G1 cyclins in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Proteolysis and DNA replication: the CDC34 requirement in the Xenopus egg cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Cyclin E-CDK2 is a regulator of p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Association of human cyclin E with a periodic G1-S phase protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The inducible elongin A elongation activation domain: structure, function and interaction with the elongin BC complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

Inhibition of transcription elongation by the VHL tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980059-2

1 reference

7 January 2021

10.1016/S0959-437X(98)80059-2

Identifiers

DOI

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8 October 2017

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PubMed ID

9529603