Autoregulation of the Raf-1 serine/threonine kinase (Q24684153)

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R M Stephens

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M R Saracino

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D K Morrison

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

4 August 1998

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published in

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volume

95

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issue

16

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page(s)

9214-9

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cites work

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Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

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14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

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The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

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MAP kinase pathways in yeast: for mating and more

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14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domain

7 April 2017

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The complexity of Raf-1 regulation

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Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras

7 April 2017

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Two distinct Raf domains mediate interaction with Ras

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Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1

7 April 2017

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Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

7 April 2017

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Multiple regulatory domains on the Byr2 protein kinase

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Mammalian Raf-1 is activated by mutations that restore Raf signaling in Drosophila

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Taxonomy and function of C1 protein kinase C homology domains

28 September 2017

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Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells

28 September 2017

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Two novel transmembrane protein tyrosine kinases expressed during Caenorhabditis elegans hypodermal development

28 September 2017

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Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes

28 September 2017

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MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

28 September 2017

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The 3Rs of life: Ras, Raf and growth regulation

28 September 2017

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The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras.

28 September 2017

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Characterization of a 78-residue fragment of c-Raf-1 that comprises a minimal binding domain for the interaction with Ras-GTP.

28 September 2017

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A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function

28 September 2017

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Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction

28 September 2017

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Molecular cloning of an activated human oncogene, homologous to v-raf, from primary stomach cancer

28 September 2017

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Activation of human raf transforming genes by deletion of normal amino-terminal coding sequences

28 September 2017

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Rat c-raf oncogene activation by a rearrangement that produces a fused protein

28 September 2017

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B-raf, a new member of the raf family, is activated by DNA rearrangement

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene

28 September 2017

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Detection of a raf-related and two other transforming DNA sequences in human tumors maintained in nude mice

28 September 2017

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Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

Mutational activation of c-raf-1 and definition of the minimal transforming sequence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

The Raf-1 kinase as a transducer of mitogenic signals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

Regulation of protein kinase C.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

Identification of the major phosphorylation sites of the Raf-1 kinase.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

The ins and outs of Raf kinases

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9214

The minimal fragments of c-Raf-1 and NF1 that can suppress v-Ha-Ras-induced malignant phenotype.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

A mechanism of c-raf-1 activation: fusion of the lipocortin II amino-terminal sequence with the c-raf-1 kinase domain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21318

Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo

28 November 2018

1 reference

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https://api.crossref.org/works/10.1073%2FPNAS.95.16.9214

Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.95.16.9214