Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting (Q24685542)

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R A Renard

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N Papadopoulos

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N W Gale

4

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G Thurston

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G D Yancopoulos

6

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S J Wiegand

Proceedings of the National Academy of Sciences of the United States of America

7

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language of work or name

English

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publication date

27 February 2007

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published in

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volume

104

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issue

9

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page(s)

3219-24

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cites work

Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis

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VEGF-Trap: a VEGF blocker with potent antitumor effects

7 April 2017

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Dll4, a novel Notch ligand expressed in arterial endothelium

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Notch signaling: cell fate control and signal integration in development

7 April 2017

1 reference

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Essential role of endothelial Notch1 in angiogenesis

7 April 2017

1 reference

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Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

7 April 2017

1 reference

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Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

7 April 2017

1 reference

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Dosage-sensitive requirement for mouse Dll4 in artery development

7 April 2017

1 reference

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The Notch target genes Hey1 and Hey2 are required for embryonic vascular development

7 April 2017

1 reference

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Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Angiogenesis as a therapeutic target

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Vascular-specific growth factors and blood vessel formation

7 April 2017

1 reference

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Notch signaling is essential for vascular morphogenesis in mice

7 April 2017

1 reference

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Mechanisms of angiogenesis and arteriogenesis

7 April 2017

1 reference

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Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

7 April 2017

1 reference

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Retinal angiogenesis in development and disease

28 September 2017

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Development and pathology of the hyaloid, choroidal and retinal vasculature.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Notch function in the vasculature: insights from zebrafish, mouse and man.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Ocular neovascularization: clarifying complex interactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Abnormal blood vessel development in mice lacking presenilin-1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805530

Oxygen-induced retinopathy in the mouse

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17296940

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Retinal vascular endothelial growth factor (VEGF) mRNA expression is altered in relation to neovascularization in oxygen induced retinopathy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17296940

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0611206104

1 reference

2338903

ADS bibcode

2007PNAS..104.3219L

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2338903

1 reference

1 reference

1 reference