The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations (Q24685574)

GOA release 2020-03-11

author name string

D O Ferguson

1

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J M Sekiguchi

2

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S Chang

3

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K M Frank

4

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Y Gao

5

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R A DePinho

6

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F W Alt

Proceedings of the National Academy of Sciences of the United States of America

7

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language of work or name

English

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publication date

6 June 2000

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published in

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volume

97

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issue

12

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page(s)

6630-3

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cites work

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Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

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Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

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Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

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The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

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Gatekeepers of recombination

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.110152897

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/10823907

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Micronucleated spermatids in the seminal fluid of smokers and nonsmokers

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.110152897

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1073/PNAS.110152897

1 reference

ADS bibcode

2000PNAS...97.6630F

0 references

1 reference

1 reference

PubMed publication ID

10823907

1 reference