The current status of targeting BAFF/BLyS for autoimmune diseases (Q24796930)

Arthritis Research and Therapy

31 July 2019

tumor necrosis factor

2 references

1 August 2019

1 February 2021

1 reference

20 November 2019

1 reference

27 November 2019

1 reference

15 December 2019

Meera Ramanujam

1

0 references

Anne Davidson

series ordinal

2

0 references

language of work or name

English

0 references

publication date

29 July 2004

8 references

30 June 2019

31 July 2019

1 August 2019

20 November 2019

27 November 2019

15 December 2019

1 February 2021

28 October 2022

8 references

30 June 2019

31 July 2019

1 August 2019

20 November 2019

27 November 2019

15 December 2019

1 February 2021

28 October 2022

6

0 references

issue

5

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page(s)

197-202

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cites work

DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF

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APRIL modulates B and T cell immunity

7 April 2017

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TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

7 April 2017

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BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

7 April 2017

1 reference

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APRIL-deficient mice have normal immune system development

7 April 2017

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Generation and characterization of LymphoStat‐B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator

7 April 2017

1 reference

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BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

7 April 2017

1 reference

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BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator

7 April 2017

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BCMA is essential for the survival of long-lived bone marrow plasma cells

7 April 2017

1 reference

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Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice

7 April 2017

1 reference

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Pathogenic roles of B cells in human autoimmunity; insights from the clinic

7 April 2017

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Peripheral B-cell maturation: the intersection of selection and homeostasis

28 September 2017

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TWE-PRIL; a fusion protein of TWEAK and APRIL

28 September 2017

1 reference

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BAFF selectively enhances the survival of plasmablasts generated from human memory B cells.

28 September 2017

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Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor

28 September 2017

1 reference

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BAFF AND APRIL: a tutorial on B cell survival

28 September 2017

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Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory".

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

G-CSF-stimulated neutrophils are a prominent source of functional BLyS

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

A single autosomal gene defect severely limits IgG but not IgM responses in B lymphocyte-deficient A/WySnJ mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Mechanism of action of transmembrane activator and calcium modulator ligand interactor-Ig in murine systemic lupus erythematosus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

BAFF production by antigen-presenting cells provides T cell co-stimulation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Engineering an APRIL-specific B cell maturation antigen

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Comparison of soluble decoy IgG fusion proteins of BAFF-R and BCMA as antagonists for BAFF.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=546289

Inflamed kidneys of NZB / W mice are a major site for the homeostasis of plasma cells

28 November 2018

1 reference

12 December 2020

Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity

1 reference

12 December 2020

BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex

1 reference

12 December 2020

Synthesis and release of B-lymphocyte stimulator from myeloid cells

1 reference

12 December 2020

TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice

1 reference

12 December 2020

Lymphoid neogenesis in rheumatoid synovitis

1 reference

12 December 2020

TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS

1 reference

12 December 2020