Tumor necrosis factor (Q21173843)

Tumour necrosis factor alpha

1 reference

inferred from GOA cell component → membrane

membrane proteins

1 reference

based on heuristic

Tumour necrosis factor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tumour necrosis factor, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

17 references

27 March 2018

Zinc finger protein tristetraprolin interacts with CCL3 mRNA and regulates tissue inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Vaccinia virus CrmE encodes a soluble and cell surface tumor necrosis factor receptor that contributes to virus virulence

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Human tumor necrosis factor-alpha receptor. Purification by immunoaffinity chromatography and initial characterization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Crystal structure of TNFα complexed with a poxvirus MHC-related TNF binding protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

The seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Structure of CrmE, a virus-encoded tumour necrosis factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

tumor necrosis factor receptor binding

IPI

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Inactivation of TNF signaling by rationally designed dominant-negative TNF variants

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

identical protein binding

4 references

27 March 2018

Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Crystal structure of TNFα complexed with a poxvirus MHC-related TNF binding protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Structure of tumour necrosis factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Inactivation of TNF signaling by rationally designed dominant-negative TNF variants

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

1 reference

27 March 2018

Ectodomain shedding of TNF-alpha is enhanced by nardilysin via activation of ADAM proteases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

integral component of membrane

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

intracellular anatomical structure

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

integral component of plasma membrane

1 reference

27 March 2018

Ectodomain shedding of TNF-alpha is enhanced by nardilysin via activation of ADAM proteases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

7 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Pro/anti-inflammatory cytokines in the pathogenesis of premature coronary artery disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Tumor necrosis factor alpha decreases, and interleukin-10 increases, the sensitivity of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Ectodomain shedding of TNF-alpha is enhanced by nardilysin via activation of ADAM proteases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of protein phosphorylation

biological process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of protein phosphorylation

3 references

27 March 2018

RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of MAP kinase activity

3 references

27 March 2018

RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

Ectodomain shedding of TNF-alpha is enhanced by nardilysin via activation of ADAM proteases

response to salt stress

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of calcidiol 1-monooxygenase activity

1 reference

27 March 2018

Tumor necrosis factor-alpha induces vitamin D-1-hydroxylase activity in normal human alveolar macrophages

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of programmed cell death

1 reference

27 March 2018

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of JNK cascade

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

response to organic substance

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of osteoblast differentiation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

27 March 2018

Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of viral genome replication

1 reference

27 March 2018

TNF-alpha inhibits HIV-1 replication in peripheral blood monocytes and alveolar macrophages by inducing the production of RANTES and decreasing C-C chemokine receptor 5 (CCR5) expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

humoral immune response

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of interleukin-8 production

1 reference

27 March 2018

The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of protein localization to cell surface

1 reference

27 March 2018

Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of ERK1 and ERK2 cascade

1 reference

27 March 2018

Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

glucose metabolic process

NAS

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

animal organ morphogenesis

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

apoptotic signaling pathway

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of alkaline phosphatase activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

27 March 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

defense response to Gram-positive bacterium

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of branching involved in salivary gland morphogenesis

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of phagocytosis

1 reference

27 March 2018

Internalization of Staphylococcus aureus by bovine endothelial cells is associated with the activity state of NF-kappaB and modulated by the pro-inflammatory cytokines TNF-alpha and IL-1beta

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of fat cell differentiation

1 reference

27 March 2018

Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of myoblast differentiation

NAS

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of protein kinase B signaling

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of insulin secretion

1 reference

27 March 2018

Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

osteoclast differentiation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of tumor necrosis factor-mediated signaling pathway

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

1 reference

27 March 2018

TNF-alpha inhibits HIV-1 replication in peripheral blood monocytes and alveolar macrophages by inducing the production of RANTES and decreasing C-C chemokine receptor 5 (CCR5) expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of osteoclast differentiation

1 reference

27 March 2018

IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of cytokine production involved in immune response

1 reference

27 March 2018

Tumor necrosis factor alpha decreases, and interleukin-10 increases, the sensitivity of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of peptidyl-serine phosphorylation

2 references

27 March 2018

RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of branching involved in lung morphogenesis

1 reference

27 March 2018

TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

death-inducing signaling complex assembly

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of osteoclast differentiation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

defense response to bacterium

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of interleukin-6 production

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

I-kappaB kinase/NF-kappaB signaling

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of translational initiation by iron

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

sequestering of triglyceride

1 reference

27 March 2018

Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of chronic inflammatory response to antigenic stimulus

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of chemokine (C-X-C motif) ligand 2 production

1 reference

27 March 2018

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of JUN kinase activity

1 reference

27 March 2018

RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of hair follicle development

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

chronic inflammatory response to antigenic stimulus

1 reference

27 March 2018

Inactivation of TNF signaling by rationally designed dominant-negative TNF variants

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

cellular response to organic cyclic compound

1 reference

27 March 2018

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

extracellular matrix organization

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of DNA-binding transcription factor activity

1 reference

27 March 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

cellular response to nicotine

1 reference

27 March 2018

Nicotine induces resistance to chemotherapy by modulating mitochondrial signaling in lung cancer

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of podosome assembly

1 reference

27 March 2018

Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of reactive oxygen species metabolic process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of protein transport

1 reference

27 March 2018

AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of glucose import

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

leukocyte tethering or rolling

1 reference

27 March 2018

Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of chemokine production

1 reference

27 March 2018

TNF-alpha inhibits HIV-1 replication in peripheral blood monocytes and alveolar macrophages by inducing the production of RANTES and decreasing C-C chemokine receptor 5 (CCR5) expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

cellular extravasation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of lipid storage

1 reference

27 March 2018

Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of myosin-light-chain-phosphatase activity

NAS

1 reference

27 March 2018

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of transcription, DNA-templated

cortical actin cytoskeleton organization

1 reference

27 March 2018

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

embryonic digestive tract development

1 reference

27 March 2018

TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

lipopolysaccharide-mediated signaling pathway

1 reference

27 March 2018

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of smooth muscle cell proliferation

1 reference

27 March 2018

Ginsenoside Rg1 inhibits tumor necrosis factor-alpha (TNF-alpha)-induced human arterial smooth muscle cells (HASMCs) proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of protein kinase activity

1 reference

27 March 2018

Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of superoxide dismutase activity

1 reference

27 March 2018

MicroRNA-21 modulates the levels of reactive oxygen species by targeting SOD3 and TNFα

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of ceramide biosynthetic process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of protein-containing complex assembly

1 reference

27 March 2018

AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

protein kinase B signaling

1 reference

27 March 2018

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of cytokine production

1 reference

27 March 2018

Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha via an NF-kappaB dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

epithelial cell proliferation involved in salivary gland morphogenesis

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of nitric oxide biosynthetic process

1 reference

27 March 2018

Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of interleukin-6 production

1 reference

27 March 2018

Tumor necrosis factor alpha decreases, and interleukin-10 increases, the sensitivity of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of membrane protein ectodomain proteolysis

1 reference

27 March 2018

The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of humoral immune response mediated by circulating immunoglobulin

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of interferon-gamma production

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

response to glucocorticoid

1 reference

27 March 2018

Tumor necrosis factor alpha decreases, and interleukin-10 increases, the sensitivity of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of vitamin D biosynthetic process

1 reference

27 March 2018

Tumor necrosis factor-alpha induces vitamin D-1-hydroxylase activity in normal human alveolar macrophages

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of mononuclear cell migration

1 reference

27 March 2018

The role of bone morphogenetic protein-5 (BMP-5) in human nephrosclerosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

1 reference

27 March 2018

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of protein-containing complex disassembly

1 reference

27 March 2018

RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

multicellular organism development

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of bicellular tight junction assembly

1 reference

27 March 2018

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of protein-containing complex disassembly

regulation of cell population proliferation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

cellular response to amino acid stimulus

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

2 references

27 March 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

cellular response to lipopolysaccharide

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of lipid catabolic process

1 reference

27 March 2018

Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of establishment of endothelial barrier

1 reference

27 March 2018

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of cell adhesion

1 reference

27 March 2018

Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of protein secretion

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of apoptotic process

4 references

27 March 2018

Bovine herpesvirus 4 BORFE2 protein inhibits Fas- and tumor necrosis factor receptor 1-induced apoptosis and contains death effector domains shared with other gamma-2 herpesviruses

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

inflammatory response

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

activation of cysteine-type endopeptidase activity involved in apoptotic process

tumor necrosis factor-mediated signaling pathway

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of I-kappaB kinase/NF-kappaB signaling

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha via an NF-kappaB dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

necroptotic signaling pathway

5 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of gene expression

8 references

27 March 2018

Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

MicroRNA-141 regulates the expression level of ICAM-1 on endothelium to decrease myocardial ischemia-reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

extrinsic apoptotic signaling pathway

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

extrinsic apoptotic signaling pathway via death domain receptors

5 references

27 March 2018

The role of bone morphogenetic protein-5 (BMP-5) in human nephrosclerosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Nicotine induces resistance to chemotherapy by modulating mitochondrial signaling in lung cancer

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

HO-1 underlies resistance of AML cells to TNF-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of transcription by RNA polymerase II

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Estrogen receptor (ER)-mediated transcriptional regulation of the human corticotropin-releasing hormone-binding protein promoter: differential effects of ERalpha and ERbeta

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Transcriptional repression of the C/EBP-alpha and GLUT4 genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. Regulations is coordinate and independent of protein synthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of NF-kappaB transcription factor activity

9 references

27 March 2018

The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Coiled-coil domain containing 3 (CCDC3) represses tumor necrosis factor-α/nuclear factor κB-induced endothelial inflammation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of transcription, DNA-templated

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Inactivation of TNF signaling by rationally designed dominant-negative TNF variants

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of transcription by RNA polymerase II

4 references

27 March 2018

NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Estrogen receptor (ER)-mediated transcriptional regulation of the human corticotropin-releasing hormone-binding protein promoter: differential effects of ERalpha and ERbeta

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of leukocyte adhesion to arterial endothelial cell

1 reference

27 March 2018

Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of leukocyte adhesion to vascular endothelial cell

1 reference

27 March 2018

MicroRNA-141 regulates the expression level of ICAM-1 on endothelium to decrease myocardial ischemia-reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of blood microparticle formation

1 reference

27 March 2018

MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of endothelial cell proliferation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of heterotypic cell-cell adhesion

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of mitotic cell cycle

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

endothelial cell apoptotic process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of vascular associated smooth muscle cell proliferation

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

negative regulation of gene expression

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Estrogen receptor (ER)-mediated transcriptional regulation of the human corticotropin-releasing hormone-binding protein promoter: differential effects of ERalpha and ERbeta

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

MicroRNA-141 regulates the expression level of ICAM-1 on endothelium to decrease myocardial ischemia-reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

protein localization to plasma membrane

1 reference

27 March 2018

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of protein catabolic process

1 reference

27 March 2018

The Npro product of classical swine fever virus interacts with IkappaBalpha, the NF-kappaB inhibitor.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of signaling receptor activity

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

regulation of inflammatory response

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

cytokine-mediated signaling pathway

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of calcineurin-NFAT signaling cascade

1 reference

27 March 2018

NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

positive regulation of NIK/NF-kappaB signaling

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

27 March 2018

Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor-alpha via an NF-kappaB dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01375&geneProductId=UniProtKB:P01375

Tumour necrosis factor, conserved site

has part(s)

1 reference

Tumour necrosis factor domain

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Commons category

Tumor necrosis factor-alpha

0 references

Identifiers

MeSH descriptor ID

D014409

subject named as

Tumor Necrosis Factor-alpha

0 references

MeSH tree code

D12.644.276.374.500.800

0 references

D12.644.276.374.750.626

0 references

D12.776.124.900

0 references

D12.776.395.930

0 references

D12.776.467.374.500.800

0 references

D12.776.467.374.750.626

0 references

0 references

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

0 references

0 references

1 reference

26 January 2022

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference