The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells (Q24800256)

5

object named as

Hans-Peter Vornlocher

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author name string

Natalia Martinez

1

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Bettina Drescher

2

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Heidemarie Riehle

3

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Claire Cullmann

4

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Arnold Ganser

6

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Gerhard Heil

7

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Alfred Nordheim

8

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Jürgen Krauter

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

9

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language of work or name

English

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publication date

6 August 2004

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published in

BMC Cancer

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volume

4

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issue

1

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page(s)

44

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cites work

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ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

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An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice

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The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

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