Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal (Q44902447)

7 December 2017

title

Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal (English)

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7 December 2017

Tonks A

1

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7 December 2017

Tonks AJ

2

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7 December 2017

Pearn L

3

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7 December 2017

Pearce L

4

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7 December 2017

Hoy T

5

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7 December 2017

Couzens S

6

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7 December 2017

Fisher J

7

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7 December 2017

Burnett AK

8

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7 December 2017

Darley RL

9

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7 December 2017

publication date

1 July 2004

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7 December 2017

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7 December 2017

volume

18

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7 December 2017

issue

7

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7 December 2017

page(s)

1238-1245

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Chromosomal translocations in human cancer.

7 December 2017

cites work

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The core-binding factor leukemias: lessons learned from murine models

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Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide

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Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

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Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

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Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation

21 January 2018

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The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

21 January 2018

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The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells

21 January 2018

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Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis

21 January 2018

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Epigenetic consequences of AML1-ETO action at the human c-FMS locus

21 January 2018

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Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation

21 January 2018

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AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency

21 January 2018

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AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

21 January 2018

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Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

21 January 2018

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Transcriptional regulation of granulocyte and monocyte development

21 January 2018

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CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

21 January 2018

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Acute myeloid leukemia with translocation (8;21). Cytomorphology, dysplasia and prognostic factors in 41 cases. AML Cooperative Group and ECOG.

21 January 2018

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t(8;21) myelodysplasia, an early presentation of M2 AML

21 January 2018

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Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

21 January 2018

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AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/SJ.LEU.2403396

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7 December 2017

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