Mechanistic studies on DNA damage by minor groove binding copper-phenanthroline conjugates (Q24816128)

4 July 2017

title

Mechanistic studies on DNA damage by minor groove binding copper-phenanthroline conjugates (English)

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4 July 2017

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5

Bernard Meunier

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4 July 2017

Brian C Bales

1

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4 July 2017

Tetsuya Kodama

2

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4 July 2017

Yvonne N Weledji

3

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4 July 2017

Marguerite Pitié

4

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4 July 2017

Marc M Greenberg

6

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4 July 2017

language of work or name

English

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publication date

26 September 2005

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4 July 2017

published in

Nucleic Acids Research

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4 July 2017

volume

33

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4 July 2017

issue

16

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4 July 2017

page(s)

5371-5379

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describes a project that uses

4 July 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1235636/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Site-specific DNA cleavage of synthetic NarL sites by an engineered Escherichia coli NarL protein-1,10-phenanthroline cleaving agent

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Oxidative Strand Scission of Nucleic Acids: Routes Initiated by Hydrogen Abstraction from the Sugar Moiety

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Mechanisms of DNA cleavage by copper complexes of 3-clip-phen and of its conjugate with a distamycin analogue

28 September 2017

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The reactivity of the 2-deoxyribonolactone lesion in single-stranded DNA and its implication in reaction mechanisms of DNA damage and repair

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DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone

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Nucleic acid chemistry of the cuprous complexes of 1,10-phenanthroline and derivatives.

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Nuclease activity of 1,10-phenanthroline-copper ion: reaction with CGCGAATTCGCG and its complexes with netropsin and EcoRI.

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The influence of reducing agent and 1,10-phenanthroline concentration on DNA cleavage by phenanthroline + copper

28 September 2017

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Oxygen-dependent cleavage of DNA by the 1,10-phenanthroline . cuprous complex. Inhibition of Escherichia coli DNA polymerase I

28 September 2017

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Changing selectivity of DNA oxidation from deoxyribose to Guanine by ligand design and a new binuclear copper complex

28 September 2017

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Large pKa shifts of alpha-carbon acids induced by copper(II) complexes

28 November 2018

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Oxygen activation by the noncoupled binuclear copper site in peptidylglycine alpha-hydroxylating monooxygenase. Spectroscopic definition of the resting sites and the putative CuIIM-OOH intermediate

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Crystal structure and nuclease activity of mono(1,10-phenanthroline) copper complex

28 November 2018

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Synthesis, crystal structure, and nuclease activity of planar mono-heterocyclic base copper(II) complexes

28 November 2018

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Acridine conjugates of 3-clip-phen: influence of the linker on the synthesis and the DNA cleavage activity of their copper complexes

28 November 2018

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A minor groove binding copper-phenanthroline conjugate produces direct strand breaks via beta-elimination of 2-deoxyribonolactone

28 November 2018

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Targeted strand scission of DNA substrates by a tricopper(II) coordination complex

28 November 2018

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Efficient and specific strand scission of DNA by a dinuclear copper complex: comparative reactivity of complexes with linked tris(2-pyridylmethyl)amine moieties

28 November 2018

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Conformation-dependent reaction thermochemistry: study of lactones and lactone enolates in the gas phase

28 November 2018

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Identification of new Fis binding sites by DNA scission with Fis-1,10-phenanthroline-copper(I) chimeras.

28 November 2018

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Chemical conversion of a DNA-binding protein into a site-specific nuclease

28 November 2018

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Cleavage of Nucleic Acids by Bleomycin

28 November 2018

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12 December 2020

Recognition and strand scission at junctions between single- and double-stranded DNA by a trinuclear copper complex

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12 December 2020

Targeting the DNA cleavage activity of copper phenanthroline and clip-phen to A.T tracts via linkage to a poly-N-methylpyrrole

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12 December 2020

DNA damage induced via independent generation of the radical resulting from formal hydrogen atom abstraction from the C1'-position of a nucleotide

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKI856

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4 July 2017

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4 July 2017

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