Molecular origin of polyglutamine aggregation in neurodegenerative diseases (Q24816819)

4 July 2017

Molecular origin of polyglutamine aggregation in neurodegenerative diseases (English)

1 reference

4 July 2017

1 reference

Feng Ding

2

0 references

Nikolay V. Dokholyan

object named as

Nikolay V Dokholyan

series ordinal

4

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author name string

Sagar D Khare

series ordinal

1

1 reference

PubMed ID

16158094

4 July 2017

Kenneth N Gwanmesia

series ordinal

3

1 reference

PubMed ID

16158094

4 July 2017

language of work or name

English

0 references

publication date

26 August 2005

1 reference

PLOS Computational Biology

4 July 2017

1 reference

4 July 2017

1

1 reference

4 July 2017

230-235

1 reference

4 July 2017

3

1 reference

Creative Commons Attribution 4.0 International

4 July 2017

start time

26 August 2005

1 reference

April 2022 Public Data File from Crossref

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Protein aggregation and neurodegenerative disease

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Protein folding and misfolding

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Molecular dynamics simulations indicate a possible role of parallel beta-helices in seeded aggregation of poly-Gln

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Folding Trp-cage to NMR resolution native structure using a coarse-grained protein model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Molecular dynamics simulation of amyloid beta dimer formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

From Alzheimer to Huntington: why is a structural understanding so difficult?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Mutational analysis of the structural organization of polyglutamine aggregates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Glutamine repeats: structural hypotheses and neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Ideas of order for amyloid fibril structure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Amyloid fibers are water-filled nanotubes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Polyglutamine pathogenesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Helix signals in proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Unusually stable helix formation in short alanine-based peptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Discrete molecular dynamics studies of the folding of a protein-like model.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Polyalanine-based peptides as models for self-associated beta-pleated-sheet complexes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Helix propensities of the amino acids measured in alanine-based peptides without helix-stabilizing side-chain interactions.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Hydrogen bonding in globular proteins

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Amyloid-like features of polyglutamine aggregates and their assembly kinetics

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193989

First-Order Disorder-to-Order Transition in an Isolated Homopolymer Model

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16158094

12 December 2020

inferred from PubMed ID database lookup

Structure of polyglutamine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16158094

12 December 2020

inferred from PubMed ID database lookup

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.0010030

7 January 2021

inferred from DOI database lookup

Studies in Molecular Dynamics. I. General Method

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.0010030

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1371/JOURNAL.PCBI.0010030

1 reference

journals/ploscb/KhareDGD05

4 July 2017

1 reference

DBLP Dataset 2021-01-02

release_mz3w5x4unfgr5ew3khpdxhjxby

28 January 2021

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mz3w5x4unfgr5ew3khpdxhjxby

24 November 2022

mapped directly with Wikidata item

PMCID

1193989

1 reference

4 July 2017

1 reference

PubMed ID

16158094