Nucleotide modification at the gamma-phosphate leads to the improved fidelity of HIV-1 reverse transcriptase. (Q24817042)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16141194%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Nucleotide modification at the gamma-phosphate leads to the improved fidelity of HIV-1 reverse transcriptase (English)

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6 January 2020

8

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6 January 2020

author name string

Brent A Mulder

1

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6 January 2020

Steve Anaya

2

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6 January 2020

Peilin Yu

3

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6 January 2020

Keun Woo Lee

4

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6 January 2020

Anvy Nguyen

5

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6 January 2020

Jason Murphy

6

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6 January 2020

Richard Willson

7

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6 January 2020

Xiaolian Gao

9

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6 January 2020

Susan H Hardin

10

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6 January 2020

language of work or name

English

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publication date

1 September 2005

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6 January 2020

published in

Nucleic Acids Research

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6 January 2020

volume

33

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issue

15

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6 January 2020

page(s)

4865-4873

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

6 January 2020

cites work

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Reverse transcriptase incorporation of 1,5-anhydrohexitol nucleotides

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Hydrogen bonding, base stacking, and steric effects in dna replication

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Functional hydrogen-bonding map of the minor groove binding tracks of six DNA polymerases

28 September 2017

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Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase

28 September 2017

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A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance.

28 September 2017

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Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase

28 September 2017

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DNA polymerase fidelity: from genetics toward a biochemical understanding

28 September 2017

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2'-Deoxynucleoside 5'-triphosphates modified at alpha-, beta- and gamma-phosphates as substrates for DNA polymerases

28 September 2017

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Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity

28 September 2017

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Differential discrimination of DNA polymerase for variants of the non-standard nucleobase pair between xanthosine and 2,4-diaminopyrimidine, two components of an expanded genetic alphabet.

28 September 2017

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Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns

28 September 2017

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Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday

28 September 2017

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Comparison between DNA melting thermodynamics and DNA polymerase fidelity

28 September 2017

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The fidelity of base selection by the polymerase subunit of DNA polymerase III holoenzyme

28 September 2017

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Fidelity mechanisms in DNA replication

28 September 2017

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Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent

28 September 2017

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28 September 2017

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Loss of polymerase activity due to Tyr to Phe substitution in the YMDD motif of human immunodeficiency virus type-1 reverse transcriptase is compensated by Met to Val substitution within the same motif

28 September 2017

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31 May 2018

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Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates

31 May 2018

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31 May 2018

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31 May 2018

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Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase-trimethoprim, a drug-receptor system.

31 May 2018

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19 June 2018

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Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase

19 June 2018

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Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase.

28 November 2018

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New substrates of DNA polymerases

28 November 2018

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Enzymatic properties of two mutants of reverse transcriptase of human immunodeficiency virus type 1 (tyrosine 181-->isoleucine and tyrosine 188-->leucine), resistant to nonnucleoside inhibitors

28 November 2018

1 reference

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Fidelity of HIV-1 reverse transcriptase

28 November 2018

1 reference

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Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase

28 November 2018

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Frameshift mutagenesis by eucaryotic DNA polymerases in vitro

28 November 2018

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12 December 2020

Replication of non-hydrogen bonded bases by DNA polymerases: a mechanism for steric matching

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12 December 2020

Spectroscopic and calorimetric characterizations of DNA duplexes containing 2-aminopurine

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12 December 2020

Effect of triphosphate modifications in 2'-deoxynucleoside 5'-triphosphates on their specificity towards various DNA polymerases

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12 December 2020

DNA Polymerase Selectivity: Sugar Interactions Monitored with High-Fidelity Nucleotides This work was supported by a grant from the Deutsche Forschungsgemeinschaft. We thank Professor Dr. Michael Famulok for his continuing support

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12 December 2020

A specific partner for abasic damage in DNA

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12 December 2020

Probing interactions between HIV-1 reverse transcriptase and its DNA substrate with backbone-modified nucleotides

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12 December 2020

The base substitution fidelity of HIV-1 reverse transcriptase on DNA and RNA templates probed with 8-oxo-deoxyguanosine triphosphate

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12 December 2020

Gamma-phosphate-substituted 2'-deoxynucleoside 5'-triphosphates as substrates for DNA polymerases

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12 December 2020

Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKI779

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16141194%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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6 January 2020

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