Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase (Q38318740)

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English	Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase	scientific article

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scholarly article

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Europe PubMed Central

2 September 2017

Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase (English)

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Europe PubMed Central

2 September 2017

1 reference

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author name string

Lewis DA

1

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Europe PubMed Central

2 September 2017

Bebenek K

2

1 reference

Europe PubMed Central

2 September 2017

Beard WA

3

1 reference

Europe PubMed Central

2 September 2017

Wilson SH

4

1 reference

Europe PubMed Central

2 September 2017

Kunkel TA

5

1 reference

Europe PubMed Central

2 September 2017

language of work or name

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publication date

1 November 1999

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Europe PubMed Central

2 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

2 September 2017

274

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Europe PubMed Central

2 September 2017

32924-32930

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Europe PubMed Central

2 September 2017

46

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Europe PubMed Central

2 September 2017

Fidelity of DNA synthesis

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Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP

1 reference

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Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

1 reference

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

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Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

1 reference

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21 January 2018

Fidelity mechanisms in DNA replication

1 reference

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21 January 2018

Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity

1 reference

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21 January 2018

The accuracy of reverse transcriptase from HIV-1.

1 reference

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Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.

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Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation

1 reference

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Marked infidelity of human immunodeficiency virus type 1 reverse transcriptase at RNA and DNA template ends

1 reference

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21 January 2018

Analyzing fidelity of DNA polymerases.

1 reference

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

1 reference

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21 January 2018

Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coli

1 reference

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21 January 2018

Reverse transcriptase motifs in the catalytic subunit of telomerase

1 reference

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Expression of polypeptides of human immunodeficiency virus-1 reverse transcriptase in Escherichia coli.

1 reference

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Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates

1 reference

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Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.

1 reference

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DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant

1 reference

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21 January 2018

A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity

1 reference

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21 January 2018

Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.

1 reference

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21 January 2018

Mutational studies of human immunodeficiency virus type 1 reverse transcriptase: the involvement of residues 183 and 184 in the fidelity of DNA synthesis

1 reference

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21 January 2018

Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.

1 reference

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Structure of the B-DNA decamer C-C-A-A-C-I-T-T-G-G in two different space groups: conformational flexibility of B-DNA

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DNA curvature and deformation in protein-DNA complexes: a step in the right direction

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21 January 2018

Structure determination and analysis of helix parameters in the DNA decamer d(CATGGCCATG)2 comparison of results from NMR and crystallography

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DNA sequence-dependent deformability deduced from protein-DNA crystal complexes

1 reference

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21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Raster3D: photorealistic molecular graphics

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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21 January 2018

DNA polymerases on the move

1 reference

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Replication of non-hydrogen bonded bases by DNA polymerases: a mechanism for steric matching

1 reference

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21 January 2018

A minor groove binding track in reverse transcriptase

1 reference

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21 January 2018

Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase. Catalytic role and inhibitor sensitivity

1 reference

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Structure/function studies of HIV-1(1) reverse transcriptase: dimerization-defective mutant L289K

1 reference

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21 January 2018

Exonucleolytic proofreading during replication of repetitive DNA

1 reference

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Base substitution specificity of DNA polymerase beta depends on interactions in the DNA minor groove

1 reference

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Base miscoding and strand misalignment errors by mutator Klenow polymerases with amino acid substitutions at tyrosine 766 in the O helix of the fingers subdomain

1 reference

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21 January 2018

Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment)

1 reference

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Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase

1 reference

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21 January 2018

Identifiers

10.1074/JBC.274.46.32924

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

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