Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons (Q26269817)

6

object named as

Marius Wernig

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author name string

Fei Yi

1

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Tamas Danko

2

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Salome Calado Botelho

3

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Christopher Patzke

4

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ChangHui Pak

Analysis of conditional heterozygous STXBP1 mutations in human neurons

5

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language of work or name

English

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publication date

6 May 2016

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published in

Science

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volume

352

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issue

6286

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page(s)

aaf2669

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cites work

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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

7 April 2017

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Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

7 April 2017

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Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits

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Absence of strong strain effects in behavioral analyses of Shank3-deficient mice

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Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission

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A blueprint for research on Shankopathies: a view from research on autism spectrum disorder

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SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties

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SHANK3 haploinsufficiency: a "common" but underdiagnosed highly penetrant monogenic cause of autism spectrum disorders

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7 January 2021

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Identifiers

DOI

10.1126/SCIENCE.AAF2669

1 reference

1 reference

1 reference

PubMed publication ID

26966193

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