Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope (Q26700120)

Kirk J Rowley

3

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Vivian V Costa

Vivian V Costa

4

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Eng Eong Ooi

Eng Eong Ooi

23

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Ram Sasisekharan

24

Ram Sasisekharan

0 references

Kannan Tharakaraman

2

Kannan Tharakaraman

0 references

Zachary Shriver

22

Zachary Shriver

0 references

Karthik Viswanathan

12

Karthik Viswanathan

0 references

Gregory J Babcock

17

Gregory J Babcock

0 references

Tyree J Koch

9

Tyree Koch

0 references

Boopathy Ramakrishnan

15

Boopathy Ramakrishnan

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author name string

Luke N Robinson

1

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Kuan Rong Chan

5

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Yee Hwa Wong

6

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Li Ching Ong

7

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Hwee Cheng Tan

8

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David Cain

10

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Rama Kirloskar

11

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Chong Wai Liew

13

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Hamid Tissire

14

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James R Myette

16

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V Sasisekharan

18

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Sylvie Alonso

19

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Jianzhu Chen

The global distribution and burden of dengue

20

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language of work or name

English

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publication date

30 July 2015

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published in

Cell

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volume

162

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page(s)

493-504

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issue

3

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cites work

1 reference

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A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface

7 April 2017

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Structural and genetic basis for development of broadly neutralizing influenza antibodies

7 April 2017

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The structural basis for serotype-specific neutralization of dengue virus by a human antibody

7 April 2017

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Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody

7 April 2017

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Dengue Plaque Reduction Neutralization Test (PRNT) in Primary and Secondary Dengue Virus Infections: How Alterations in Assay Conditions Impact Performance

7 April 2017

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Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody

7 April 2017

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Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II

7 April 2017

1 reference

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Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins

7 April 2017

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Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma

7 April 2017

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Overview of the CCP4 suite and current developments

7 April 2017

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Scaling and assessment of data quality

7 April 2017

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Shape complementarity at protein/protein interfaces

7 April 2017

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Cross-reacting antibodies enhance dengue virus infection in humans

7 April 2017

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Conformations of immunoglobulin hypervariable regions

7 April 2017

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Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

7 April 2017

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Predominant autoantibody production by early human B cell precursors

7 April 2017

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Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

7 April 2017

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A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

28 September 2017

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Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial

28 September 2017

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First experimental in vivo model of enhanced dengue disease severity through maternally acquired heterotypic dengue antibodies

28 September 2017

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Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue

28 September 2017

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The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein

28 September 2017

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Analysis of cross-reactive antibodies recognizing the fusion loop of envelope protein and correlation with neutralizing antibody titers in Nicaraguan dengue cases

28 September 2017

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Inhibition of megakaryocyte development in the bone marrow underlies dengue virus-induced thrombocytopenia in humanized mice

28 September 2017

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Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection

28 September 2017

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Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency

28 September 2017

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Neutralization of dengue virus in the presence of Fc receptor-mediated phagocytosis distinguishes serotype-specific from cross-neutralizing antibodies

28 September 2017

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Therapeutics for dengue: recommendations for design and conduct of early-phase clinical trials

28 September 2017

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Variation in dengue virus plaque reduction neutralization testing: systematic review and pooled analysis

28 September 2017

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Antibodies targeting dengue virus envelope domain III are not required for serotype-specific protection or prevention of enhancement in vivo

28 September 2017

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Recombinant dengue type 2 viruses with altered e protein domain III epitopes are efficiently neutralized by human immune sera

28 September 2017

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28 September 2017

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Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection

28 September 2017

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28 September 2017

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The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

28 September 2017

1 reference

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28 September 2017

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Interference of immune globulin with measles and rubella immunization

28 September 2017

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Dengue Virus-Specific and Flavivirus Group Determinants Identified with Monoclonal Antibodies by Indirect Immunofluorescence

28 September 2017

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28 September 2017

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31 May 2018

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31 May 2018

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10.1016/J.CELL.2015.06.057

28 November 2018

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