Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma (Q26752400)

pancreatic ductal adenocarcinoma

inferred from title

1 reference

pancreatic ductal carcinoma

inferred from title

1 reference

Norihiro Sato

1

0 references

Xiao-Bo Cheng

2

0 references

Shiro Kohi

3

0 references

Atsuhiro Koga

4

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Keiji Hirata

Acta Pharmaceutica Sinica B

5

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language of work or name

English

0 references

publication date

March 2016

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published in

1 reference

Key Roles of Hyaluronan and Its CD44 Receptor in the Stemness and Survival of Cancer Stem Cells

volume

6

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page(s)

101-5

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issue

2

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cites work

1 reference

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Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer

7 April 2017

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

7 April 2017

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7 April 2017

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A novel epigenetic mechanism regulating hyaluronan production in pancreatic cancer cells

7 April 2017

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Receptor for Hyaluronic Acid-Mediated Motility is Associated with Poor Survival in Pancreatic Ductal Adenocarcinoma

28 September 2017

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Dietary supplement 4-methylumbelliferone: an effective chemopreventive and therapeutic agent for prostate cancer

28 September 2017

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4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer

28 September 2017

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Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

28 September 2017

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CD44 regulates pancreatic cancer invasion through MT1-MMP

28 September 2017

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A novel role of low molecular weight hyaluronan in breast cancer metastasis

28 September 2017

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Accumulation of small hyaluronan oligosaccharides in tumour interstitial fluid correlates with lymphatic invasion and lymph node metastasis.

28 September 2017

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Glycyrrhizin suppresses lung adenocarcinoma cell growth through inhibition of thromboxane synthase

28 September 2017

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Prognostic impact of hyaluronan and its regulators in pancreatic ductal adenocarcinoma

28 September 2017

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Chemotherapy-induced hyaluronan production: a novel chemoresistance mechanism in ovarian cancer

28 September 2017

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Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer.

28 September 2017

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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

28 September 2017

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Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look

28 September 2017

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Targeting hyaluronidase for cancer therapy: antitumor activity of sulfated hyaluronic acid in prostate cancer cells

28 September 2017

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Hyaluronan-CD44 interactions as potential targets for cancer therapy.

28 September 2017

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Hyaluronan in human malignancies

28 September 2017

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Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities

28 September 2017

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Navigating ECM barriers at the invasive front: the cancer cell-stroma interface

28 September 2017

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Phosphoinositide 3-kinase inhibitor (wortmannin) inhibits pancreatic cancer cell motility and migration induced by hyaluronan in vitro and peritoneal metastasis in vivo

28 September 2017

1 reference

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4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3.

28 September 2017

1 reference

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Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progression

28 September 2017

1 reference

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Inhibitory effect of 4-methylesculetin on hyaluronan synthesis slows the development of human pancreatic cancer in vitro and in nude mice

28 September 2017

1 reference

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The role of epigenetic alterations in pancreatic cancer

28 September 2017

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Study of hyaluronan synthase inhibitor, 4-methylumbelliferone derivatives on human pancreatic cancer cell (KP1-NL).

28 September 2017

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Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragments

28 September 2017

1 reference

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Hyaluronan catabolism: a new metabolic pathway

28 September 2017

1 reference

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Hyaluronan: from extracellular glue to pericellular cue.

28 September 2017

1 reference

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A novel mechanism for the inhibition of hyaluronan biosynthesis by 4-methylumbelliferone

28 September 2017

1 reference

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Mammalian hyaluronan synthases

28 September 2017

1 reference

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Hyaluronan activates cell motility of v-Src-transformed cells via Ras-mitogen-activated protein kinase and phosphoinositide 3-kinase-Akt in a tumor-specific manner

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

Differential expression of the hyaluronan receptors CD44 and RHAMM in human pancreatic cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

Interactions between human tumor cells and fibroblasts stimulate hyaluronate synthesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

Hyaluronan is a secretory product of human pancreatic adenocarcinoma cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

Effective targeting of the tumor microenvironment for cancer therapy.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

4-methylumbelliferone, a hyaluronan synthase suppressor, enhances the anticancer activity of gemcitabine in human pancreatic cancer cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

The impact of extracellular matrix on the chemoresistance of solid tumors--experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788704

The significance of CD44 in human pancreatic cancer: II. The role of CD44 in human pancreatic adenocarcinoma invasion

28 November 2018

1 reference

12 December 2020

Targeting tumor architecture to favor drug penetration: a new weapon to combat chemoresistance in pancreatic cancer?

1 reference

12 December 2020

Localisation of hyaluronate (HA) in primary tumors and nude mouse xenografts of human pancreatic carcinomas using a biotinylated HA-binding protein

1 reference

12 December 2020

Pancreatic carcinoma is characterized by elevated content of hyaluronan and chondroitin sulfate with altered disaccharide composition

1 reference

12 December 2020

The impact of extracellular matrix on chemoresistance of solid tumors--experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.APSB.2016.01.002

7 January 2021