At the Crossroads of Nanotoxicology in vitro: Past Achievements and Current Challenges (Q26796677)

2

0 references

Sheung P Ng

3

0 references

Kristen K Comfort

4

0 references

Christin M Grabinski

5

0 references

Laura K Braydich-Stolle

6

0 references

language of work or name

English

0 references

publication date

September 2015

0 references

published in

Toxicological Sciences

1 reference

Effects of nanomaterial physicochemical properties on in vivo toxicity.

PubMed

volume

147

0 references

issue

1

0 references

page(s)

5-16

0 references

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

The gold standard: gold nanoparticle libraries to understand the nano-bio interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nanotoxicology and in vitro studies: the need of the hour

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Review of carbon nanotubes toxicity and exposure--appraisal of human health risk assessment based on open literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Direct exposure methods for testing native atmospheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Application of surface chemical analysis tools for characterization of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Microfluidic organs-on-chips.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Aggregation kinetics and transport of single-walled carbon nanotubes at low surfactant concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Minimal analytical characterization of engineered nanomaterials needed for hazard assessment in biological matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

In vitro cytotoxicity of nanoparticles in mammalian germline stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nanosized aluminum altered immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Dynamic characteristics of silver nanoparticles in physiological fluids: toxicological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Particle size-dependent total mass deposition in lungs determines inhalation toxicity of cadmium chloride aerosols in rats. Application of a multiple path dosimetry model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Role of target geometry in phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

The effect of sedimentation and diffusion on cellular uptake of gold nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nanoparticle characterization: state of the art, challenges, and emerging technologies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

An integrated approach for the in vitro dosimetry of engineered nanomaterials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Interference of silver, gold, and iron oxide nanoparticles on epidermal growth factor signal transduction in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Less is more: long-term in vitro exposure to low levels of silver nanoparticles provides new insights for nanomaterial evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Slow release of ions from internalized silver nanoparticles modifies the epidermal growth factor signaling response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

High aspect ratio gold nanorods displayed augmented cellular internalization and surface chemistry mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Carbon nanotubes: present and future commercial applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Differential lung inflammation and injury with tobacco smoke exposure in Wistar Kyoto and spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Cellular interaction and toxicity depend on physicochemical properties and surface modification of redox-active nanomaterials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Physico-chemical features of engineered nanoparticles relevant to their toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Workshop report: strategies for setting occupational exposure limits for engineered nanomaterials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Effect of gold nanorod surface chemistry on cellular response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Carbon nanotubes leading the way forward in new generation 3D tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Effects of various physicochemical characteristics on the toxicities of ZnO and TiO nanoparticles toward human lung epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Reconstituting organ-level lung functions on a chip

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

In vitro toxicity of nanoparticles in BRL 3A rat liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nano aerosol chamber for in-vitro toxicity (NACIVT) studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nanoparticle-mediated cellular response is size-dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: comparison with conventional monocultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Engineered nanoparticles in consumer products: understanding a new ingredient

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Bioaccumulation dynamics and modeling in an estuarine invertebrate following aqueous exposure to nanosized and dissolved silver

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

The delivered dose: Applying particokinetics to in vitro investigations of nanoparticle internalization by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Tuning payload delivery in tumour cylindroids using gold nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Perceptions and experiences of research participants on gender-based violence community based survey: implications for ethical guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Techniques for physicochemical characterization of nanomaterials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Analysis of nanoparticle agglomeration in aqueous suspensions via constant-number Monte Carlo simulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Assessing nanoparticle toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Impact of high-throughput screening in biomedical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Mechanisms of nanoparticle-induced oxidative stress and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Photocatalytical nanocomposites: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

The role of interparticle and external forces in nanoparticle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Comparative study using spheres, rods and spindle-shaped nanoplatelets on dispersion stability, dissolution and toxicity of CuO nanomaterials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Biomolecular coronas provide the biological identity of nanosized materials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Effect of gold nanosphere surface chemistry on protein adsorption and cell uptake in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Toxic potential of materials at the nanolevel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Understanding biophysicochemical interactions at the nano-bio interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Altered protein expression profile associated with phenotypic changes in lung fibroblasts co-cultured with gold nanoparticle-treated small airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Concern-driven integrated approaches to nanomaterial testing and assessment--report of the NanoSafety Cluster Working Group 10

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Toxicity of engineered nanomaterials: a physicochemical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

The nanomaterial characterization bottleneck

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Concept of assessing nanoparticle hazards considering nanoparticle dosemetric and chemical/biological response metrics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Applications of nanoparticles in biology and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Analyzing nanomaterial bioconjugates: a review of current and emerging purification and characterization techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Characterization of nanomaterials for toxicity assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Toxicity of nanomaterials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Superparamagnetic iron oxide nanoparticles alter expression of obesity and T2D-associated risk genes in human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Endosomal escape: a bottleneck in intracellular delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nanomaterial cytotoxicity is composition, size, and cell type dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Particokinetics in vitro: dosimetry considerations for in vitro nanoparticle toxicity assessments

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

The effects of particle size, density and shape on margination of nanoparticles in microcirculation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

In vitro toxicological screening of nanoparticles on primary human endothelial cells and the role of flow in modulating cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Tannic acid coated gold nanorods demonstrate a distinctive form of endosomal uptake and unique distribution within cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Microfluidic technologies for accelerating the clinical translation of nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Harmonization of measurement strategies for exposure to manufactured nano-objects: report of a workshop

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Direct particle-to-cell deposition of coarse ambient particulate matter increases the production of inflammatory mediators from cultured human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Nanoscale and fine zinc oxide particles: can in vitro assays accurately forecast lung hazards following inhalation exposures?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

How to measure hazards/risks following exposures to nanoscale or pigment-grade titanium dioxide particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Macrophage responses to silica nanoparticles are highly conserved across particle sizes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

High-throughput screening platform for engineered nanoparticle-mediated genotoxicity using CometChip technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Biophysical responses upon the interaction of nanomaterials with cellular interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Aerosolized ZnO nanoparticles induce toxicity in alveolar type II epithelial cells at the air-liquid interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Positive surface charge enhances selective cellular uptake and anticancer efficacy of selenium nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Complementary analysis of the hard and soft protein corona: sample preparation critically effects corona composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

Noble metal nanomaterials: Controllable synthesis and application in fuel cells and analytical sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

Pulmonary toxicity study in rats with three forms of ultrafine-TiO2 particles: Differential responses related to surface properties

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

Effect of Surface Charge on the Uptake and Distribution of Gold Nanoparticles in Four Plant Species

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

Surface Composition Tuning of Au–Pt Bimetallic Nanoparticles for Enhanced Carbon Monoxide and Methanol Electro-oxidation

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

Effect of particle shape on phagocytosis of CdTe quantum dot–cystine composites

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

Silver nanoparticle characterization using single particle ICP-MS (SP-ICP-MS) and asymmetrical flow field flow fractionation ICP-MS (AF4-ICP-MS)

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

Nanoparticle–protein corona complexes govern the biological fates and functions of nanoparticles

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

Deposition, retention, and translocation of ultrafine particles from the central airways and lung periphery

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

DNA damage of macrophages at an air-tissue interface induced by metal nanoparticles

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021

The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFV106

7 January 2021