Regulatory T-Cell Development in the Human Thymus (Q26797326)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284077%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Regulatory T-Cell Development in the Human Thymus (English)

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22 February 2020

1

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22 February 2020

Helena Nunes-Cabaço

series ordinal

2

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22 February 2020

Ana E. Sousa

series ordinal

4

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22 February 2020

author name string

Russell B Foxall

series ordinal

3

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22 February 2020

language of work or name

English

0 references

publication date

3 August 2015

1 reference

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22 February 2020

published in

Frontiers in Immunology

2 references

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22 February 2020

volume

6

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22 February 2020

page(s)

395

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Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human thymus

22 February 2020

cites work

1 reference

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Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

7 April 2017

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Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

7 April 2017

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Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor

7 April 2017

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FOXP3+ regulatory T cells in the human immune system

7 April 2017

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Regulatory T cells: mechanisms of differentiation and function

7 April 2017

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

7 April 2017

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

7 April 2017

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Thymic B cells promote thymus-derived regulatory T cell development and proliferation

7 April 2017

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Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligand

28 September 2017

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A microRNA profile of human CD8(+) regulatory T cells and characterization of the effects of microRNAs on Treg cell-associated genes

28 September 2017

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Combined immunodeficiencies with nonfunctional T lymphocytes

28 September 2017

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Immunodeficiency in DiGeorge Syndrome and Options for Treating Cases with Complete Athymia

28 September 2017

1 reference

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Human APECED; a Sick Thymus Syndrome?

28 September 2017

1 reference

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Repairing thymic function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Dynamics of thymus organogenesis and colonization in early human development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Human FOXN1-deficiency is associated with αβ double-negative and FoxP3+ T-cell expansions that are distinctly modulated upon thymic transplantation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Selection of regulatory T cells in the thymus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Rare development of Foxp3+ thymocytes in the CD4+CD8+ subset

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

CD8+ suppressor T cells resurrected.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Differentiation of regulatory Foxp3+ T cells in the thymic cortex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Expression of CD103 identifies human regulatory T-cell subsets

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Experimental models to study development and function of the human immune system in vivo

28 September 2017

1 reference

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Specific control of immunity by regulatory CD8 T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Functional features of human CD25+ regulatory thymocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

CD4(+) CD25(+) T-cell production in healthy humans and in patients with thymic hypoplasia.

28 September 2017

1 reference

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Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro

28 September 2017

1 reference

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Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells.

28 September 2017

1 reference

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Early human T cell development: analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment

28 September 2017

1 reference

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Traffic of mature lymphocytes into the mouse thymus

28 September 2017

1 reference

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Thymic stromal alterations and genetic disorders of immune system

28 September 2017

1 reference

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Molecular mechanisms underlying FOXP3 induction in human T cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Selective engraftment of donor CD4+25high FOXP3-positive T cells in IPEX syndrome after nonmyeloablative hematopoietic stem cell transplantation

31 May 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Regulatory T cell defect in APECED patients is associated with loss of naive FOXP3(+) precursors and impaired activated population.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Insight into normal thymic activity by assessment of peripheral blood samples.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Thymus transplantation restores the repertoires of forkhead box protein 3 (FoxP3)+ and FoxP3- T cells in complete DiGeorge anomaly.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Development and activation of regulatory T cells in the human fetus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

The FOXP3+ subset of human CD4+CD8+ thymocytes is immature and subject to intrathymic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Foxp3 induction in human and murine thymus precedes the CD4+ CD8+ stage but requires early T-cell receptor expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Differentiation of human thymic regulatory T cells at the double positive stage.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Human regulatory T-cell development is dictated by Interleukin-2 and -15 expressed in a non-overlapping pattern in the thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Human CD4+CD25+ regulatory T cells share equally complex and comparable repertoires with CD4+CD25- counterparts

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Cutting edge: size and diversity of CD4+CD25high Foxp3+ regulatory T cell repertoire in humans: evidence for similarities and partial overlapping with CD4+CD25- T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

E-cadherin-mediated interactions of thymic epithelial cells with CD103+ thymocytes lead to enhanced thymocyte cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Ontogeny of CD4+CD25+ regulatory/suppressor T cells in human fetuses

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Expansion of FOXP3+ CD8 T cells with suppressive potential in colorectal mucosa following a pathogenic simian immunodeficiency virus infection correlates with diminished antiviral T cell response and viral control

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

Cutting edge: human CD4-CD8- thymocytes express FOXP3 in the absence of a TCR

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522873

Dynamics of Thymus-Colonizing Cells during Human Development

28 November 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00395

ζ Chain-associated protein of 70 kDa (ZAP70) deficiency in human subjects is associated with abnormalities of thymic stromal cells: Implications for T-cell tolerance

21 January 2018

1 reference

12 December 2020

Transient accumulation of human mature thymocytes and regulatory T cells with CD28 superagonist in "human immune system" Rag2(-/-)gammac(-/-) mice

1 reference

12 December 2020

Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development

1 reference

12 December 2020

Helios expression in T-regulatory cells in patients with di George Syndrome

1 reference

12 December 2020

A Role for Intrathymic B Cells in the Generation of Natural Regulatory T Cells

1 reference

12 December 2020

A monoclonal antibody (HML-1) defining a novel membrane molecule present on human intestinal lymphocytes

1 reference

12 December 2020

Most human thymic and peripheral-blood CD4+ CD25+ regulatory T cells express 2 T-cell receptors

1 reference

12 December 2020

Immunologic defects in 22q11.2 deletion syndrome

1 reference

12 December 2020

A defect of regulatory T cells in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

1 reference

12 December 2020

Peripheral T lymphocytes recirculating back into the thymus can mediate thymocyte positive selection

1 reference

12 December 2020

Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue

1 reference

12 December 2020

Development of CD4+ CD25+ FoxP3+ regulatory T cells from cord blood hematopoietic progenitor cells

1 reference

12 December 2020

Regulation of T cell responses in the developing human fetus

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2015.00395

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284077%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284077%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

26284077

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284077%20AND%20SRC:MED&resulttype=core&format=json