The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung (Q26822879)

Rosell R

series ordinal

2

1 reference

Viteri S

series ordinal

3

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language of work or name

1 reference

June 2013

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Translational lung cancer research

published in

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volume

2

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issue

3

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page(s)

172-9

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Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties

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Evidence that SOX2 overexpression is oncogenic in the lung

7 April 2017

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SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas

7 April 2017

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The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer

7 April 2017

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A distinct "side population" of cells with high drug efflux capacity in human tumor cells

7 April 2017

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Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer

7 April 2017

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7 April 2017

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7 April 2017

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Vertebrate neurogenesis is counteracted by Sox1-3 activity

7 April 2017

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Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm

7 April 2017

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Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation

7 April 2017

1 reference

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

7 April 2017

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LKB1 modulates lung cancer differentiation and metastasis

7 April 2017

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EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

25 May 2017

1 reference

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Increased Sox2 copy number in lung squamous cell carcinomas

28 September 2017

1 reference

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

28 September 2017

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Detection of MET and SOX2 amplification by quantitative real-time PCR in non-small cell lung carcinoma

28 September 2017

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SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells

28 September 2017

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Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

28 September 2017

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SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.

28 September 2017

1 reference

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Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

28 September 2017

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Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma.

28 September 2017

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Expression of pluripotent stem cell reprogramming factors by prostate tumor initiating cells

28 September 2017

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Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

28 September 2017

1 reference

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Back to basics: Sox genes

28 September 2017

1 reference

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Characterization of stem cell-like cancer cells in immune-competent mice

28 September 2017

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Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells

28 September 2017

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Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma

28 September 2017

1 reference

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SOX2 in squamous cell carcinoma: amplifying a pleiotropic oncogene along carcinogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

SOX2 is highly expressed in squamous cell carcinomas of the gastrointestinal tract

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

Sox2 expression in pulmonary non-small cell and neuroendocrine carcinomas

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor.

28 November 2018

1 reference

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Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598

28 November 2018

Small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25806230

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SOX2 amplification is a common event in squamous cell carcinomas of different organ sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/25806230

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3978/J.ISSN.2218-6751.2013.01.01

0 references

1 reference

PubMed publication ID

25806230

1 reference