Molecular evolution of GPCRs: GLP1/GLP1 receptors (Q26823392)

G protein-coupled receptor

main subject

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author name string

J.-I. Hwang

1

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S. Yun

2

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M. J. Moon

3

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C. R. Park

4

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J. Y. Seong

5

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language of work or name

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June 2014

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Journal of Molecular Endocrinology

published in

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volume

52

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issue

3

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page(s)

T15-27

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The bioactive conformation of glucose-dependent insulinotropic polypeptide by NMR and CD spectroscopy

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Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets

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Molecular modeling of the three-dimensional structure of GLP-1R and its interactions with several agonists

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Tyr1 and Ile7 of Glucose-Dependent Insulinotropic Polypeptide (GIP) Confer Differential Ligand Selectivity toward GIP and Glucagon-like Peptide-1 Receptors

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Insulin contributes to fine-tuning of the pancreatic beta-cell response to glucagon-like peptide-1.

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Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences

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Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei

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Characterization of the receptors for chicken GHRH and GHRH-related peptides: identification of a novel receptor for GHRH and the receptor for GHRH-LP (PRP).

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7 January 2021

Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy

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Conformational and molecular interaction studies of glucagon-like peptide-2 with its N-terminal extracellular receptor domain

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GIP and GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice.

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7 January 2021

Class-B GPCR activation: is ligand helix-capping the key?

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Molecular evolution of neuropeptide receptors with regard to maintaining high affinity to their authentic ligands

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Revisiting the evolution of gonadotropin-releasing hormones and their receptors in vertebrates: secrets hidden in genomes

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7 January 2021

The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge

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7 January 2021

Cellular and molecular biology of orphan G protein-coupled receptors

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7 January 2021

Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study

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7 January 2021

Structural determinants for activity of glucagon-like peptide-2.

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7 January 2021

Structure of glucagon-like peptide (7-36) amide in a dodecylphosphocholine micelle as determined by 2D NMR

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7 January 2021

Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states

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7 January 2021

More genes in vertebrates?

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7 January 2021

The amphioxus genome and the evolution of the chordate karyotype

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7 January 2021

Structure of the human glucagon class B G-protein-coupled receptor

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7 January 2021

Evidence of en bloc duplication in vertebrate genomes

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7 January 2021

Glucagon-like peptide-1 receptor is involved in learning and neuroprotection

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7 January 2021

Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity

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7 January 2021

A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors.

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7 January 2021

Mutational analysis of the glucagon receptor: similarities with the vasoactive intestinal peptide (VIP)/pituitary adenylate cyclase-activating peptide (PACAP)/secretin receptors for recognition of the ligand's third residue

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7 January 2021

Characterization of insulins and proglucagon-derived peptides from a phylogenetically ancient fish, the paddlefish (Polyodon spathula)

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7 January 2021

NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor

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7 January 2021

Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor

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7 January 2021

Molecular basis for negative regulation of the glucagon receptor

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7 January 2021

Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor

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7 January 2021

Molecular evolution of peptidergic signaling systems in bilaterians

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7 January 2021

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line

1 reference

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7 January 2021

The Xenopus proglucagon gene encodes novel GLP-1-like peptides with insulinotropic properties.

1 reference

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7 January 2021

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

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7 January 2021

Molecular basis of glucagon-like peptide 1 docking to its intact receptor studied with carboxyl-terminal photolabile probes

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7 January 2021

Spatial approximations between residues 6 and 12 in the amino-terminal region of glucagon-like peptide 1 and its receptor: a region critical for biological activity

1 reference

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7 January 2021

Evolutionarily conserved residues at glucagon-like peptide-1 (GLP-1) receptor core confer ligand-induced receptor activation

1 reference

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7 January 2021

Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation

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7 January 2021

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis

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7 January 2021

Three distinct epitopes on the extracellular face of the glucagon receptor determine specificity for the glucagon amino terminus

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7 January 2021

Identification of amino acid residues that direct differential ligand selectivity of mammalian and nonmammalian V1a type receptors for arginine vasopressin and vasotocin. Insights into molecular coevolution of V1a type receptors and their ligands

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7 January 2021

Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

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7 January 2021

Evolution of New Hormone Function: Loss and Gain of a Receptor

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7 January 2021

Systematic phylogenomic evidence of en bloc duplication of the ancestral 8p11.21-8p21.3-like region

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7 January 2021

Expansion of secretin-like G protein-coupled receptors and their peptide ligands via local duplications before and after two rounds of whole-genome duplication

1 reference

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7 January 2021

Lamprey proglucagon and the origin of glucagon-like peptides

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7 January 2021

Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome

1 reference

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7 January 2021

The human Hox-bearing chromosome regions did arise by block or chromosome (or even genome) duplications

1 reference

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7 January 2021

Reconstruction of the vertebrate ancestral genome reveals dynamic genome reorganization in early vertebrates

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Evolutionary conservation of regulatory elements in vertebrate Hox gene clusters

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Structure/activity characterization of glucagon-like peptide-1

1 reference

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7 January 2021

Incretin hormones and the expanding families of glucagon-like sequences and their receptors

1 reference

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7 January 2021

cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Receptors for VIP, PACAP, secretin, GRF, glucagon, GLP-1, and other members of their new family of G protein-linked receptors: structure-function relationship with special reference to the human VIP-1 receptor

1 reference

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7 January 2021

Extracellular loop 3 (EL3) and EL3-proximal transmembrane helix 7 of the mammalian type I and type II gonadotropin-releasing hormone (GnRH) receptors determine differential ligand selectivity to GnRH-I and GnRH-II.

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Identification of determinants of glucose-dependent insulinotropic polypeptide receptor that interact with N-terminal biologically active region of the natural ligand.

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

The serendipitous origin of chordate secretin peptide family members

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Evolution of secretin family GPCR members in the metazoa.

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Family-B G-protein-coupled receptors

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7 January 2021

Insulinotropic hormone glucagon-like peptide-I(7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma beta TC-1 cells

1 reference

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7 January 2021

Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C.

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Molecular evolution of multiple forms of kisspeptins and GPR54 receptors in vertebrates.

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Discovery of a novel glucagon-like peptide (GCGL) and its receptor (GCGLR) in chickens: evidence for the existence of GCGL and GCGLR genes in nonmammalian vertebrates

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

The glucagon-like peptides

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https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis

1 reference

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7 January 2021

Position of Pro and Ser near Glu7.32in the Extracellular Loop 3 of Mammalian and Nonmammalian Gonadotropin-Releasing Hormone (GnRH) Receptors Is a Critical Determinant for Differential Ligand Selectivity for Mammalian GnRH and Chicken GnRH-II

1 reference

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7 January 2021

Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Using paleogenomics to study the evolution of gene families: origin and duplication history of the relaxin family hormones and their receptors

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Agnathan VIP, PACAP and their receptors: ancestral origins of today's highly diversified forms

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

A novel glucagon-related peptide (GCRP) and its receptor GCRPR account for coevolution of their family members in vertebrates

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Structure-activity relationships of glucose-dependent insulinotropic polypeptide (GIP).

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Characterization of glucagon-like peptide-1 receptor-binding determinants

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Harnessing the therapeutic potential of glucagon-like peptide-1: a critical review

1 reference

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7 January 2021

Met-204 and Tyr-205 are together important for binding GLP-1 receptor agonists but not their N-terminally truncated analogues

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Leptin directly depolarizes preproglucagon neurons in the nucleus tractus solitarius: electrical properties of glucagon-like Peptide 1 neurons

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

1 reference

https://api.crossref.org/works/10.1530%2FJME-13-0137

7 January 2021

Identifiers

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PubMed publication ID

24598200

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