Why does the bone marrow fail in Fanconi anemia? (Q26823574)

K. J. Patel

series ordinal

2

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language of work or name

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2 January 2014

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123

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PubMed

issue

1

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PubMed

page(s)

26-34

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Basal metabolic rates in mammals: taxonomic differences in the allometry of BMR and body mass.

PubMed

cites work

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https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Malignant transformation initiated by Mll-AF9: gene dosage and critical target cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Mechanism of replication-coupled DNA interstrand crosslink repair

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

The origin and evolution of mutations in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Localization-dependent and -independent roles of SLX4 in regulating telomeres

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

DNA repair is crucial for maintaining hematopoietic stem cell function

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Fanconi anemia and its diagnosis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Fanconi anemia: myelodysplasia as a predictor of outcome

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Kinetics and specificity of human liver aldehyde dehydrogenases toward aliphatic, aromatic, and fused polycyclic aldehydes

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

[13C2]-Acetaldehyde promotes unequivocal formation of 1,N2-propano-2'-deoxyguanosine in human cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Identification of DNA adducts of acetaldehyde.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Oxygen-dependence of chromosomal aberrations in Fanconi's anaemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Cloning of cDNAs for Fanconi's anaemia by functional complementation

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Mutations of the SLX4 gene in Fanconi anemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Guido Fanconi (1892-1979): a jack of all trades.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Stem cell collection and gene transfer in Fanconi anemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

The Fanconi anemia polypeptide FACC is localized to the cytoplasm

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Localization of Fanconi anemia C protein to the cytoplasm of mammalian cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase "Asian" variant

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Oxidative stress in Fanconi anemia hematopoiesis and disease progression

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

FANCE: the link between Fanconi anaemia complex assembly and activity

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

DNA repair deficiency and acetaldehyde-induced chromosomal alterations in CHO cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Cytokine production by bone marrow mononuclear cells in inherited bone marrow failure syndromes

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Biallelic inactivation of BRCA2 in Fanconi anemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Mechanism of RAD51-dependent DNA interstrand cross-link repair.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

A 20-year perspective on the International Fanconi Anemia Registry (IFAR).

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Individualized risks of first adverse events in patients with Fanconi anemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Continuous in vivo infusion of interferon-gamma (IFN-gamma) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc-/- mice

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

FANCL ubiquitinates β-catenin and enhances its nuclear function

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Overcoming reprogramming resistance of Fanconi anemia cells

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Fetal origins of hematopoietic failure in a murine model of Fanconi anemia

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

TNF-alpha regulates the effects of irradiation in the mouse bone marrow microenvironment.

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021

Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient mice

1 reference

https://api.crossref.org/works/10.1182%2FBLOOD-2013-09-427740

7 January 2021