Vascular protection to increase the safety of tissue plasminogen activator for stroke (Q26824338)

Soliman S

2

1 reference

Guan W

3

1 reference

Saler M

4

1 reference

Fagan SC

5

1 reference

language of work or name

1 reference

2012

1 reference

Current Pharmaceutical Design

published in

1 reference

volume

18

1 reference

issue

25

1 reference

page(s)

3677-84

1 reference

Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC

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Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activator

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Combination therapy of 17beta-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke

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Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein

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Admission hyperglycemia predicts a worse outcome in stroke patients treated with intravenous thrombolysis

28 September 2017

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Tissue plasminogen activator (tPA) and matrix metalloproteinases in the pathogenesis of stroke: therapeutic strategies

28 September 2017

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Delayed matrix metalloproteinase inhibition reduces intracerebral hemorrhage after embolic stroke in rats

28 September 2017

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Acute ischemic stroke treatment in 2007.

28 September 2017

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Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia

28 September 2017

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Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors

28 September 2017

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Mast cell blocking reduces brain edema and hematoma volume and improves outcome after experimental intracerebral hemorrhage

28 September 2017

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Low density lipoprotein receptor-related proteins (LRPs), Alzheimer's and cognition

28 September 2017

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Cerebral mast cells regulate early ischemic brain swelling and neutrophil accumulation

28 September 2017

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Stroke epidemiology in the developing world

28 September 2017

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Attenuation of extravasation of tissue plasminogen activator by the free radical scavenger, edaravone: evaluation in a rat thromboembolic stroke model

28 September 2017

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Multiple roles for MMPs and TIMPs in cerebral ischemia

28 September 2017

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Tactics for vascular protection after acute ischemic stroke

28 September 2017

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Lost in translation: taking neuroprotection from animal models to clinical trials.

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Activated protein C and ischemic stroke

28 September 2017

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Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.

28 September 2017

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Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke.

28 September 2017

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Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats

28 September 2017

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Reactive oxygen radicals in signaling and damage in the ischemic brain

28 September 2017

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Pharmacological effects of the spin trap agents N-t-butyl-phenylnitrone (PBN) and 2,2,6, 6-tetramethylpiperidine-N-oxyl (TEMPO) in a rabbit thromboembolic stroke model: combination studies with the thrombolytic tissue plasminogen activator

28 September 2017

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The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

28 September 2017

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Use of tissue-type plasminogen activator for acute ischemic stroke: the Cleveland area experience

28 September 2017

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Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

28 September 2017

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Localization of tissue plasminogen activator in the endothelium of a limited number of vessels

28 September 2017

1 reference

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Extension of the thrombolytic time window with minocycline in experimental stroke.

28 September 2017

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Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C.

31 May 2018

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Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice

31 May 2018

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Hypertension and its treatment in the NINDS rt-PA Stroke Trial

31 May 2018

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Differential matrix metalloproteinase expression in cases of multiple sclerosis and stroke

31 May 2018

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Cilostazol reduces the risk of hemorrhagic infarction after administration of tissue-type plasminogen activator in a murine stroke model

31 May 2018

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Combination of tissue-plasminogen activator with erythropoietin induces blood-brain barrier permeability, extracellular matrix disaggregation, and DNA fragmentation after focal cerebral ischemia in mice.

28 November 2018

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Postthrombolysis Blood Pressure Elevation Is Associated With Hemorrhagic Transformation

28 November 2018

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Pre-tissue plasminogen activator blood pressure levels and risk of symptomatic intracerebral hemorrhage

28 November 2018

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Albumin ameliorates tissue plasminogen activator-mediated blood-brain barrier permeability and ischemic brain injury in rats

28 November 2018

1 reference

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Dissociation and protection of the neurovascular unit after thrombolysis and reperfusion in ischemic rat brain

28 November 2018

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Tacrolimus (FK506) suppresses rt-PA-induced hemorrhagic transformation in a rat thrombotic ischemia stroke model

28 November 2018

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Early disruption of the blood-brain barrier after thrombolytic therapy predicts hemorrhage in patients with acute stroke.

28 November 2018

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Tissue-type plasminogen activator as a therapeutic target in stroke

28 November 2018

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Mast cell stabilization reduces hemorrhage formation and mortality after administration of thrombolytics in experimental ischemic stroke.

28 November 2018

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Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice

28 November 2018

1 reference

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Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects

28 November 2018

1 reference

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Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage

28 November 2018

1 reference

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Evaluating therapeutic targets for reperfusion-related brain hemorrhage

28 November 2018

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Role of matrix metalloproteinases in delayed cortical responses after stroke

28 November 2018

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Melatonin attenuates the postischemic increase in blood-brain barrier permeability and decreases hemorrhagic transformation of tissue-plasminogen activator therapy following ischemic stroke in mice

28 November 2018

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Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia.

28 November 2018

1 reference

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Pharmacology of caffeinol in embolized rabbits: clinical rating scores and intracerebral hemorrhage incidence

28 November 2018

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Coadministration of NXY-059 and tenecteplase six hours following embolic strokes in rabbits improves clinical rating scores

28 November 2018

1 reference

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Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia.

28 November 2018

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Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator

28 November 2018

1 reference

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Cell Type-Specific Roles for Tissue Plasminogen Activator Released by Neurons or Microglia after Excitotoxic Injury

28 November 2018

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Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke Trial

28 November 2018

1 reference

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Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke

28 November 2018

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Effects of the spin trap agent disodium- [tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit Large clot embolic stroke model: combination studies with tissue plasminogen activator

28 November 2018

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Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator

28 November 2018

1 reference

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Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats

28 November 2018

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Gelatinase B and TIMP-1 are regulated in a cell- and time-dependent manner in association with neuronal death and glial reactivity after global forebrain ischemia.

28 November 2018

1 reference

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The nonpeptide glycoprotein IIb/IIIa platelet receptor antagonist SM-20302 reduces tissue plasminogen activator-induced intracerebral hemorrhage after thromboembolic stroke

28 November 2018

1 reference

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Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trial

28 November 2018

1 reference

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Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.

28 November 2018

1 reference

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Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke.

28 November 2018

1 reference

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Acute hypertension after stroke: the scientific basis for treatment decisions.

28 November 2018

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28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602899

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

28 November 2018

1 reference

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Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study Group

28 November 2018

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12 December 2020

NXY-059 for the treatment of acute ischemic stroke

1 reference

12 December 2020

Nitrite does not provide additional protection to thrombolysis in a rat model of stroke with delayed reperfusion

1 reference

12 December 2020

Reduction of tissue plasminogen activator-induced hemorrhage and brain injury by free radical spin trapping after embolic focal cerebral ischemia in rats

1 reference

12 December 2020

tPA and proteolysis in the neurovascular unit

1 reference

12 December 2020

An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus

1 reference

12 December 2020

Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke

1 reference

12 December 2020

10.2174/138161212802002779

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

22574982

1 reference