Role of the lipoperoxidation product 4-hydroxynonenal in the pathogenesis of severe malaria anemia and malaria immunodepression (Q26825559)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25969702%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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Evelin Schwarzer

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1

2 references

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11 June 2020

Paolo Arese

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2

2 references

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11 June 2020

language of work or name

1 reference

2015

1 reference

Oxidative medicine and cellular longevity

19 April 2015

3 references

23 March 2019

7 November 2019

14 January 2024

5 references

23 March 2019

7 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25969702%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

14 January 2024

2015

2 references

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11 June 2020

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638416

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Creative Commons Attribution 3.0 Unported

11 June 2020

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23 March 2019

7 November 2019

on focus list of Wikimedia project

14 January 2024

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cites work

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Transfer of 4-hydroxynonenal from parasitized to non-parasitized erythrocytes in rosettes. Proposed role in severe malaria anemia

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Inhibition of erythropoiesis in malaria anemia: role of hemozoin and hemozoin-generated 4-hydroxynonenal

28 September 2017

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Comparative analysis of gene expression changes mediated by individual constituents of hemozoin

28 September 2017

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Hemozoin and the human monocyte--a brief review of their interactions.

28 September 2017

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Erythroblastic islands: niches for erythropoiesis

28 September 2017

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4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest.

28 September 2017

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Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo

28 September 2017

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Reactive lipid species from cyclooxygenase-2 inactivate tumor suppressor LKB1/STK11: cyclopentenone prostaglandins and 4-hydroxy-2-nonenal covalently modify and inhibit the AMP-kinase kinase that modulates cellular energy homeostasis and protein tra

28 September 2017

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Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma

28 September 2017

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Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells: a peroxisome proliferator-activated receptor-gamma-mediated effect

28 September 2017

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Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions

28 September 2017

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A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.

28 September 2017

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Basic aspects of the biochemical reactivity of 4-hydroxynonenal

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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31 May 2018

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31 May 2018

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31 May 2018

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Detection of short-chain carbonyl products of lipid peroxidation from malaria-parasite (Plasmodium vinckei)-infected red blood cells exposed to oxidative stress

31 May 2018

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Metabolism of the lipid peroxidation product 4-hydroxynonenal by isolated hepatocytes and by liver cytosolic fractions

31 May 2018

1 reference

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Inhibition by reactive aldehydes of superoxide anion radical production from stimulated polymorphonuclear leukocytes and pulmonary alveolar macrophages. Effects on cellular sulfhydryl groups and NADPH oxidase activity

31 May 2018

1 reference

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Increased plasma lipid peroxidation in riboflavin-deficient, malaria-infected children.

31 May 2018

1 reference

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Impairment of macrophage functions after ingestion of Plasmodium falciparum-infected erythrocytes or isolated malarial pigment.

31 May 2018

1 reference

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Reactive nitrogen intermediates and outcome in severe adult malaria.

31 May 2018

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Evidence for erythrocyte lipid peroxidation in acute falciparum malaria.

21 January 2018

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Blood oxidative stress markers and Plasmodium falciparum malaria in non-immune African children

21 January 2018

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Aldehydes from n-6 fatty acid peroxidation. Effects on aminophospholipids

21 January 2018

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Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses

21 January 2018

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Pyridoxamine: an extremely potent scavenger of 1,4-dicarbonyls

21 January 2018

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Increased levels of 4-hydroxynonenal in human monocytes fed with malarial pigment hemozoin. A possible clue for hemozoin toxicity.

21 January 2018

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Physicochemical and immunological studies on 4-hydroxynonenal modified HSA: implications of protein damage by lipid peroxidation products in the etiopathogenesis of SLE.

21 January 2018

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Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation

21 January 2018

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Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal.

21 January 2018

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4-Hydroxy-2-nonenal is a powerful endogenous inhibitor of endothelial response

21 January 2018

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Oxidative stress in renal anemia of hemodialysis patients is mitigated by epoetin treatment

21 January 2018

1 reference

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beta-Hematin (hemozoin) mediated decompostion of polyunsaturated fatty acids to 4-hydroxy-2-nonenal

21 January 2018

1 reference

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Role of 4-hydroxynonenal in the hemozoin-mediated inhibition of differentiation of human monocytes to dendritic cells induced by GM-CSF/IL-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F638416

Severity of anaemia is associated with bone marrow haemozoin in children exposed to Plasmodium falciparum.

21 January 2018

1 reference

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Differential carbonylation of cytoskeletal proteins in blood group O erythrocytes: potential role in protection against severe malaria.

21 January 2018

1 reference

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Malarial pigment hemozoin impairs chemotactic motility and transendothelial migration of monocytes via 4-hydroxynonenal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F638416

Hemozoin- and 4-hydroxynonenal-mediated inhibition of erythropoiesis. Possible role in malarial dyserythropoiesis and anemia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417603

The lipid peroxidation product, 4-hydroxy-2-trans-nonenal, alters the conformation of cortical synaptosomal membrane proteins.

28 November 2018

1 reference

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Plasma antioxidants and lipid peroxidation products in falciparum malaria.

28 November 2018

1 reference

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Covalent modifications of aminophospholipids by 4-hydroxynonenal

28 November 2018

1 reference

12 December 2020

Formation of cyclic adducts of deoxyguanosine with the aldehydes trans-4-hydroxy-2-hexenal and trans-4-hydroxy-2-nonenal in vitro

1 reference

12 December 2020

Increased levels of 4-hydroxynonenal modified proteins in plasma of children with autoimmune diseases

1 reference

12 December 2020

Monoclonal antibodies for detection of 4-hydroxynonenal modified proteins

1 reference

12 December 2020

Metabolic fate of 4-hydroxynonenal in hepatocytes: 1,4-dihydroxynonene is not the main product

1 reference

12 December 2020

Phagocytosis of P. falciparum malarial pigment hemozoin by human monocytes inactivates monocyte protein kinase C

1 reference

12 December 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25969702%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25969702%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25969702%20AND%20SRC:MED&resulttype=core&format=json