Wnt signaling pathway in non-small cell lung cancer (Q26825936)

non-small-cell lung carcinoma

main subject

1 reference

D. J. Stewart

1

1 reference

language of work or name

1 reference

January 2014

1 reference

Journal of the National Cancer Institute

published in

1 reference

volume

106

1 reference

issue

1

1 reference

page(s)

djt356

1 reference

cites work

Global cancer statistics

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

21 January 2018

Cancer statistics, 2013

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Tumor and host factors that may limit efficacy of chemotherapy in non-small cell and small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Targeting Wnt signaling: can we safely eradicate cancer stem cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt signaling in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt5b stimulates adipogenesis by activating PPARgamma, and inhibiting the beta-catenin dependent Wnt signaling pathway together with Wnt5a

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

sFRP1 inhibits epithelial-mesenchymal transition in A549 human lung adenocarcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Lung cancer in mice induced by the jaagsiekte sheep retrovirus envelope protein is not maintained by rare cancer stem cells, but tumorigenicity does correlate with Wnt pathway activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

A systematic-analysis of predicted miR-21 targets identifies a signature for lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Interactions between cancer stem cells and their niche govern metastatic colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Aberrant Wnt1/β-catenin expression is an independent poor prognostic marker of non-small cell lung cancer after surgery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt1 overexpression promotes tumour progression in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt pathway activation predicts increased risk of tumor recurrence in patients with stage I nonsmall cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

A novel sLRP6E1E2 inhibits canonical Wnt signaling, epithelial-to-mesenchymal transition, and induces mitochondria-dependent apoptosis in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt3 gene expression promotes tumor progression in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Down-regulation of canonical and up-regulation of non-canonical Wnt signalling in the carcinogenic process of squamous cell lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Adenoviral vector expressing short hairpin RNA targeting Wnt2B has an effective antitumour activity against Wnt2B2-overexpressing tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt5a: its signalling, functions and implication in diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt5a is associated with cigarette smoke-related lung carcinogenesis via protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt11 in 2011 - the regulation and function of a non-canonical Wnt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Antitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5-dependent activation of peroxisome proliferator-activated receptor gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Analysis of Wnt7a-stimulated JNK activity and cJun phosphorylation in non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

CAFET algorithm reveals Wnt/PCP signature in lung squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

WNT7a induces E-cadherin in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

EMMPRIN regulates the canonical Wnt/beta-catenin signaling pathway, a potential role in accelerating lung tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Sulindac suppresses beta-catenin expression in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

The expression of beta-catenin in non-small-cell lung cancer: a clinicopathological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Mutations of the beta- and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Constitutive activation of the Wnt signaling pathway by CTNNB1 (beta-catenin) mutations in a subset of human lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Frizzled-8 as a putative therapeutic target in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Dishevelled family proteins are expressed in non-small cell lung cancer and function differentially on tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Suppression of PPN/MG61 attenuates Wnt/beta-catenin signaling pathway and induces apoptosis in human lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Cell biology. The unusual case of Porcupine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Genetic Variants in MMP9 and TCF2 Contribute to Susceptibility to Lung Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Abnormal expression of Pygopus 2 correlates with a malignant phenotype in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

APC mutations are infrequent but present in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Evidence for tankyrases as antineoplastic targets in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

EMX2 is epigenetically silenced and suppresses growth in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Suppression of Wnt signaling by the miR-29 family is mediated by demethylation of WIF-1 in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Transcriptional inactivation of secreted frizzled-related protein 1 by promoter hypermethylation as a potential biomarker for non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt signaling promoter hypermethylation distinguishes lung primary adenocarcinomas from colorectal metastasis to the lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

WIF1, a component of the Wnt pathway, is down‐regulated in prostate, breast, lung, and bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

DNA Methylation status of Wnt antagonist SFRP5 can predict the response to the EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Down-regulation of NKD1 increases the invasive potential of non-small-cell lung cancer and correlates with a poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

ING4 induces cell growth inhibition in human lung adenocarcinoma A549 cells by means of Wnt-1/beta-catenin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Abnormal hypermethylation and clinicopathological significance of Axin gene in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Brain metastases exhibit gross deletions of the APC gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Tobacco smoke induces polycomb-mediated repression of Dickkopf-1 in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wif1 hypermethylation as unfavorable prognosis of non-small cell lung cancers with EGFR mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

The hypomethylation agent bisdemethoxycurcumin acts on the WIF-1 promoter, inhibits the canonical Wnt pathway and induces apoptosis in human non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt inhibitory factor inhibits lung cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Transcriptional regulation of livin by beta-catenin/TCF signaling in human lung cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Inhibition of cytoplasmic GSK-3β increases cisplatin resistance through activation of Wnt/β-catenin signaling in A549/DDP cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Anti-HDGF targets cancer and cancer stromal stem cells resistant to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

2,3,6-Trisubstituted quinoxaline derivative, a small molecule inhibitor of the Wnt/beta-catenin signaling pathway, suppresses cell proliferation and enhances radiosensitivity in A549/Wnt2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Drugging the Wnt pathway: problems and progress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Winning WNT: race to Wnt signaling inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Fool's gold, lost treasures, and the randomized clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

Increased expression of beta-catenin predicts better prognosis in nonsmall cell lung carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Downregulation of HDPR1 is associated with poor prognosis and affects expression levels of p120-catenin and beta-catenin in nonsmall cell lung cancer

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial-mesenchymal transdifferentiation and cancer stem-like properties and in lung adenocarcinoma

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Distinct effects of sonic hedgehog and Wnt-7a on differentiation of neonatal neural stem/progenitor cells in vitro

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Pilot phase I-II study on 5-aza-2'-deoxycytidine (Decitabine) in patients with metastatic lung cancer

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

The expression patterns and correlations of chibby, β-catenin, and DNA methyltransferase-1 and their clinicopathological significance in lung cancers

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Wnt5a expression is associated with the tumor proliferation and the stromal vascular endothelial growth factor--an expression in non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Overexpression of axin downregulates TCF-4 and inhibits the development of lung cancer

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Molecular characterization of chronic obstructive pulmonary disease-related non-small cell lung cancer through aberrant methylation and alterations of EGFR signaling

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Clinical significance and prognostic value of serum Dickkopf-1 concentrations in patients with lung cancer

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJT356

7 January 2021

Identifiers

DOI

10.1093/JNCI/DJT356

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

24309006

1 reference

Consolidated OpenCitations Corpus – April 2017