Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans (Q28482937)

1

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David J Stewart

2

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J Jack Lee

3

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Lin Ji

4

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Rajagopal Ramesh

5

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Gitanjali Jayachandran

6

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Maria I Nunez

7

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Jeremy J Erasmus

9

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Marshall E Hicks

10

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Elizabeth A Grimm

11

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James M Reuben

12

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Veerabhadran Baladandayuthapani

13

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Nancy S Templeton

14

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John D McMannis

15

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Jack A Roth

Creative Commons Attribution 4.0 International

16

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language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

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issue

4

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page(s)

e34833

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copyright license

start time

25 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo

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The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

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29 September 2017

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29 September 2017

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Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer c

29 September 2017

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Comprehensive analysis of the acute toxicities induced by systemic administration of cationic lipid:plasmid DNA complexes in mice

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Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma

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In vitro and in vivo liposome-mediated gene transfer leads to human MDR1 expression in mouse bone marrow progenitor cells

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Molecular themes in oncogenesis

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Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector

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Identification and removal of colanic acid from plasmid DNA preparations: implications for gene therapy

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Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma

2 June 2018

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2 June 2018

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2 June 2018

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Reversible mode of binding of serum proteins to DOTAP/cholesterol Lipoplexes: a possible explanation for intravenous lipofection efficiency

20 June 2018

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Increased uptake of liposomal-DNA complexes by lung metastases following intravenous administration

21 January 2018

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Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector

21 January 2018

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Potential limitations of transcription terminators used as transgene insulators in adenoviral vectors.

21 January 2018

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The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element.

21 January 2018

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Bacterial DNA is implicated in the inflammatory response to delivery of DNA/DOTAP to mouse lungs

21 January 2018

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Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22558101

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22558101

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0034833

1 reference

ADS bibcode

2012PLoSO...734833L

0 references

1 reference

1 reference

PubMed publication ID

22558101

1 reference