S1PR2 links germinal center confinement and growth regulation (Q26829249)

Jason G. Cyster

series ordinal

2

1 reference

language of work or name

1 reference

May 2012

1 reference

published in

Immunological Reviews

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volume

247

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issue

1

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page(s)

36-51

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Oxysterols direct immune cell migration via EBI2

cites work

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Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

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A chemokine-driven positive feedback loop organizes lymphoid follicles

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Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction

7 April 2017

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Bcl6 mediates the development of T follicular helper cells

7 April 2017

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7 April 2017

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EBI2 mediates B cell segregation between the outer and centre follicle

7 April 2017

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7 April 2017

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Oxysterols direct B-cell migration through EBI2

7 April 2017

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Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

7 April 2017

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Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII

7 April 2017

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Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3

7 April 2017

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Cell migration: Rho GTPases lead the way

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7 April 2017

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Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers

28 September 2017

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EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues

28 September 2017

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The sphingosine 1-phosphate receptor S1P₂ maintains the homeostasis of germinal center B cells and promotes niche confinement

28 September 2017

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Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone

28 September 2017

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Lipid phosphate phosphatase 3 enables efficient thymic egress

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B cells within germinal centers migrate preferentially from dark to light zone.

28 September 2017

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The outs and the ins of sphingosine-1-phosphate in immunity

28 September 2017

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Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo

28 September 2017

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Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1.

28 September 2017

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Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

28 September 2017

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Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

28 September 2017

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The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.

28 September 2017

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Control systems and decision making for antibody production.

28 September 2017

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Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses

28 September 2017

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Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

28 September 2017

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Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84.

28 September 2017

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Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation.

28 September 2017

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Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

28 September 2017

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Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

28 September 2017

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Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

28 September 2017

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Stromal cell contributions to the homeostasis and functionality of the immune system.

28 September 2017

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Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation.

28 September 2017

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B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis.

28 September 2017

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SAP-controlled T-B cell interactions underlie germinal centre formation

28 September 2017

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The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis

28 September 2017

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Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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31 May 2018

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PI3 kinase signals BCR-dependent mature B cell survival

31 May 2018

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Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles

31 May 2018

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Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/Akt signaling pathways in vascular endothelial cells

31 May 2018

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Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells

31 May 2018

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Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

31 May 2018

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Visualization of specific B and T lymphocyte interactions in the lymph node.

31 May 2018

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Lymphotoxin-alpha-deficient and TNF receptor-I-deficient mice define developmental and functional characteristics of germinal centers

31 May 2018

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B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells

31 May 2018

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Maturation of the immune response in germinal centers

31 May 2018

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The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues.

31 May 2018

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Affinity maturation without germinal centres in lymphotoxin-alpha-deficient mice.

21 January 2018

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21 January 2018

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G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Imaging of germinal center selection events during affinity maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

AID constrains germinal center size by rendering B cells susceptible to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

B cell receptor signal strength determines B cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Bam32/DAPP1 promotes B cell adhesion and formation of polarized conjugates with T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

The pleckstrin homology domain adaptor protein Bam32/DAPP1 is required for germinal center progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

An essential role for Akt1 in dendritic cell function and tumor immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

CXCR5-deficient mice develop functional germinal centers in the splenic T cell zone.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335345

Vav-Dependent and Vav-Independent Phosphatidylinositol 3-Kinase Activation in Murine B Cells Determined by the Nature of the Stimulus

28 November 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2012.01114.X

Cell growth control by G protein-coupled receptors: from signal transduction to signal integration

21 January 2018

1 reference

12 December 2020

VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE

1 reference

12 December 2020

Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help

1 reference

12 December 2020

Normal acute and chronic inflammatory responses in sphingosine kinase 1 knockout mice

1 reference

12 December 2020

The germinal center response is impaired in the absence of T cell-expressed CXCR5

1 reference

12 December 2020

The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells

1 reference

12 December 2020

CD19-deficient mice exhibit poor responsiveness to oral immunization despite evidence of unaltered total IgA levels, germinal centers and IgA-isotype switching in Peyer's patches

1 reference

12 December 2020

Antigen persistence is required for somatic mutation and affinity maturation of immunoglobulin

1 reference

12 December 2020

Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells

1 reference

12 December 2020

IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade

1 reference

12 December 2020

Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses

1 reference

12 December 2020