Novel insights into pericyte-myofibroblast transition and therapeutic targets in renal fibrosis (Q26852520)

Yu-Hsiang Chou

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2

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Yi-Ting Chen

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Shuei-Liong Lin

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4

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language of work or name

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November 2012

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Journal of the Formosan Medical Association

published in

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volume

111

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issue

11

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page(s)

589-98

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Modulation of mts1 expression in mouse and human normal and tumor cells

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Conditional abatement of tissue fibrosis using nucleoside analogs to selectively corrupt DNA replication in transgenic fibroblasts

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NG2 proteoglycan expression by pericytes in pathological microvasculature.

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Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat.

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Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis

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Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival

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Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis

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Conditional ablation of macrophages halts progression of crescentic glomerulonephritis

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Plasma concentration of immunoreactive vascular endothelial growth factor and its relation to smoking

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Regulation of alpha-smooth muscle actin gene expression in myofibroblast differentiation from rat lung fibroblasts

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The role of capillary density, macrophage infiltration and interstitial scarring in the pathogenesis of human chronic kidney disease

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Origin of new cells in the adult kidney: results from genetic labeling techniques

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Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis

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WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

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A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2

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Renal fibrosis: novel insights into mechanisms and therapeutic targets.

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Specific molecular targeting of renal injury in obstructive nephropathy

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Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats.

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Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro

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Basic fibroblast growth factor expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation

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Progression in chronic kidney disease.

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A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis

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7 January 2021

VEGF inhibition and renal thrombotic microangiopathy

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7 January 2021

Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis

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7 January 2021

Macrophage Wnt7b is critical for kidney repair and regeneration

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7 January 2021

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

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Orchestration of angiogenesis and arteriovenous contribution by angiopoietins and vascular endothelial growth factor (VEGF).

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METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity

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Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells

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Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

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Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3.

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Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

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7 January 2021

Vascular endothelial growth factor (VEGF) and its receptors

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7 January 2021

Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo

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7 January 2021

Differential roles of PDGFR-alpha and PDGFR-beta in angiogenesis and vessel stability.

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7 January 2021

Peritubular capillary regression during the progression of experimental obstructive nephropathy.

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Vascular endothelial growth factor, left ventricular dysfunction and mortality in hemodialysis patients.

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7 January 2021

Mechanisms of fibrosis: the role of the pericyte

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MicroRNAs and fibrosis

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Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall

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Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family

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7 January 2021

Antibodies against macrophages that overlap in specificity with fibroblasts

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7 January 2021

Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury

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7 January 2021

A pericyte origin of spinal cord scar tissue

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7 January 2021

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

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7 January 2021

Serum amyloid P inhibits fibrosis through Fc gamma R-dependent monocyte-macrophage regulation in vivo.

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7 January 2021

MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways

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7 January 2021

Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature.

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7 January 2021

Myeloid cell function in MRP-14 (S100A9) null mice

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7 January 2021

Evidence that inhibition of tubular cell apoptosis protects against renal damage and development of fibrosis following ureteric obstruction

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7 January 2021

Noncanonical TGF-beta pathways, mTORC1 and Abl, in renal interstitial fibrogenesis

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7 January 2021

Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction

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7 January 2021

Elevated plasma vascular endothelial growth factor levels in non-diabetic predialysis uraemia

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7 January 2021

Transforming growth factor-β and Smads

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7 January 2021

Role of ADAMTS-1 in atherosclerosis: remodeling of carotid artery, immunohistochemistry, and proteolysis of versican.

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7 January 2021

Endothelial/pericyte interactions

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7 January 2021

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

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7 January 2021

Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells.

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7 January 2021

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

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7 January 2021

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

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7 January 2021

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

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7 January 2021

Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells

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https://api.crossref.org/works/10.1016%2FJ.JFMA.2012.09.008

7 January 2021

Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney

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7 January 2021

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

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7 January 2021

Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans

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7 January 2021

Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice

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7 January 2021

VEGF(165) mediates glomerular endothelial repair

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Obligatory participation of macrophages in an angiopoietin 2-mediated cell death switch

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Hepatic stellate cells: unique characteristics in cell biology and phenotype

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PRM-151 (recombinant human serum amyloid P/pentraxin 2) for the treatment of fibrosis

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Mural cell associated VEGF is required for organotypic vessel formation

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Multiple organ engraftment by bone-marrow-derived myofibroblasts and fibroblasts in bone-marrow-transplanted mice.

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7 January 2021

Wound healing in the kidney: complex interactions in renal interstitial fibrogenesis

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7 January 2021

Bone marrow-derived cells do not contribute significantly to collagen I synthesis in a murine model of renal fibrosis.

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7 January 2021

Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury.

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7 January 2021

Professor Toshio Ito: a clairvoyant in pericyte biology

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Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

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7 January 2021

Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease

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7 January 2021

Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury

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7 January 2021

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

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https://api.crossref.org/works/10.1016%2FJ.JFMA.2012.09.008

7 January 2021

Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells

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https://api.crossref.org/works/10.1016%2FJ.JFMA.2012.09.008

7 January 2021

Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts.

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7 January 2021

Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations.

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7 January 2021

10.1016/J.JFMA.2012.09.008

Identifiers

DOI

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PubMed publication ID

23217594

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