Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans (Q34245363)

31 July 2017

Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans (English)

1 reference

31 July 2017

Bernhard Bielesz

1

0 references

Katalin Susztak

object named as

Katalin Susztak

11

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Volker H. Haase

object named as

Volker H Haase

10

0 references

Manfred Gessler

object named as

Manfred Gessler

9

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author name string

Yasemin Sirin

2

1 reference

31 July 2017

Han Si

3

1 reference

31 July 2017

Thiruvur Niranjan

4

1 reference

31 July 2017

Antje Gruenwald

5

1 reference

31 July 2017

Seonho Ahn

6

1 reference

31 July 2017

Hideki Kato

7

1 reference

31 July 2017

James Pullman

8

1 reference

31 July 2017

language of work or name

English

0 references

publication date

18 October 2010

1 reference

Journal of Clinical Investigation

31 July 2017

1 reference

31 July 2017

120

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31 July 2017

4040-4054

1 reference

31 July 2017

11

1 reference

TGFbeta signalling: a complex web in cancer progression

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Differential expression of claudin tight junction proteins in the human cortical nephron

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

EMT: when epithelial cells decide to become mesenchymal-like cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Intrinsic epithelial cells repair the kidney after injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Ectopic notch activation in developing podocytes causes glomerulosclerosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Molecular insights into segmentation along the proximal-distal axis of the nephron.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch signaling is necessary for epithelial growth arrest by TGF-beta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Hypoxia requires notch signaling to maintain the undifferentiated cell state

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

The role of Notch signaling in specification of podocyte and proximal tubules within the developing mouse kidney.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Direct regulation of intestinal fate by Notch

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Differential expression of E-cadherin, N-cadherin and beta-catenin in proximal and distal segments of the rat nephron

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Epithelial-mesenchymal transition and its implications for fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Evidence that fibroblasts derive from epithelium during tissue fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

A role for Wnt-4 in renal fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

How does podocyte damage result in tubular damage?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Disruption of the mouse RBP-J kappa gene results in early embryonic death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Tubulointerstitial changes as a major determinant in the progression of renal damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Uremic memory: the role of acute kidney injury in long-term outcomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

The Notch pathway in podocytes plays a role in the development of glomerular disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964979

Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978353

12 December 2020

inferred from PubMed ID database lookup

The pathogenic role of Notch activation in podocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978353

12 December 2020

inferred from PubMed ID database lookup

State-specific trends in chronic kidney failure--United States, 1990-2001

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978353

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1172/JCI43025

1 reference

release_zdahpkhj2redvdqgj3efnhun5a

31 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zdahpkhj2redvdqgj3efnhun5a

24 November 2022

mapped directly with Wikidata item

PMCID

2964979

1 reference

31 July 2017

1 reference