Genetic contribution to osteoarthritis development: current state of evidence (Q26852663)

genetic predisposition to disease

19 September 2019

2 references

23 July 2020

10 September 2020

genome-wide association study

1 reference

11 August 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775188%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

John Loughlin

series ordinal

1

1 reference

Crossref

language of work or name

1 reference

May 2015

1 reference

Current Opinion in Rheumatology

1 May 2015

5 references

13 March 2019

17 June 2019

19 September 2019

23 July 2020

11 August 2020

7 references

13 March 2019

17 June 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775188%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

23 July 2020

11 August 2020

27

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775188%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

3

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775188%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

284-288

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775188%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

6 June 2020

copyright license

5 references

13 March 2019

17 June 2019

19 September 2019

23 July 2020

on focus list of Wikimedia project

11 August 2020

ScienceSource

0 references

cites work

Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Individuals with primary osteoarthritis have different phenotypes depending on the affected joint - a case control study from southern sweden including 514 participants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Epigenetic differences in human cartilage between mild and severe OA.

28 September 2017

1 reference

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Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Characterization of the cartilage DNA methylome in knee and hip osteoarthritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Insights from human genetic studies into the pathways involved in osteoarthritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

The identification of trans-acting factors that regulate the expression of GDF5 via the osteoarthritis susceptibility SNP rs143383.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

The genetics and functional analysis of primary osteoarthritis susceptibility.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423655

Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25775188

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/BOR.0000000000000171

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775188%20AND%20SRC:MED&resulttype=core&format=json

release_4kmlyxmttfh55cctzakpr3gxou

6 June 2020

Fatcat ID

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775188%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775188%20AND%20SRC:MED&resulttype=core&format=json