The genetics and functional analysis of primary osteoarthritis susceptibility. (Q36620051)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

23 July 2020

The genetics and functional analysis of primary osteoarthritis susceptibility (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

3 references

13 March 2019

17 June 2019

23 July 2020

genetic predisposition to disease

1 reference

23 July 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Louise N Reynard

series ordinal

1

1 reference

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24 February 2020

publication date

18 February 2013

5 references

13 March 2019

17 June 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

23 July 2020

10 September 2020

Expert Reviews in Molecular Medicine

5 references

13 March 2019

17 June 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

23 July 2020

10 September 2020

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

e2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls

24 February 2020

cites work

1 reference

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Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data

30 September 2017

1 reference

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Control of arthritis pain with anti-nerve-growth factor: risk and benefit

30 September 2017

1 reference

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A rare variant in the osteoarthritis-associated locus GDF5 is functional and reveals a site that can be manipulated to modulate GDF5 expression.

30 September 2017

1 reference

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Positive selection on the osteoarthritis-risk and decreased-height associated variants at the GDF5 gene in East Asians

30 September 2017

1 reference

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Leveraging models of cell regulation and GWAS data in integrative network-based association studies

30 September 2017

1 reference

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Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

30 September 2017

1 reference

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Central role of SREBP-2 in the pathogenesis of osteoarthritis

30 September 2017

1 reference

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Evolution and functional impact of rare coding variation from deep sequencing of human exomes

30 September 2017

1 reference

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Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

30 September 2017

1 reference

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Quantitative proteomic analysis of eight cartilaginous tissues reveals characteristic differences as well as similarities between subgroups

30 September 2017

1 reference

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Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

30 September 2017

1 reference

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A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype

30 September 2017

1 reference

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Osteoarthritis: a disease of the joint as an organ

30 September 2017

1 reference

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Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs.

30 September 2017

1 reference

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Differential protein profiling of synovial fluid from rheumatoid arthritis and osteoarthritis patients using LC-MALDI TOF/TOF.

30 September 2017

1 reference

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Applications of proteomics to osteoarthritis, a musculoskeletal disease characterized by aging

30 September 2017

1 reference

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The expression and function of microRNAs in chondrogenesis and osteoarthritis.

30 September 2017

1 reference

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The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review

30 September 2017

1 reference

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A variant in MCF2L is associated with osteoarthritis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis

30 September 2017

1 reference

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All cause and disease specific mortality in patients with knee or hip osteoarthritis: population based cohort study

30 September 2017

1 reference

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The role of mitochondria in osteoarthritis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

RNA sequencing: advances, challenges and opportunities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study

30 September 2017

1 reference

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A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22

30 September 2017

1 reference

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Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

30 September 2017

1 reference

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Differential transcriptome analysis of intraarticular lesional vs intact cartilage reveals new candidate genes in osteoarthritis pathophysiology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

Common variants in the GDF5-UQCC region are associated with variation in human height

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

Meta-analysis of association between the ASPN D-repeat and osteoarthritis

30 September 2017

1 reference

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Genome studies and linkage in primary osteoarthritis

30 September 2017

1 reference

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Recent explosive human population growth has resulted in an excess of rare genetic variants

30 September 2017

1 reference

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Testing the druggable endothelial differentiation gene 2 knee osteoarthritis genetic factor for replication in a wide range of sample collections

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575889

A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis

28 June 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Genetics of osteoarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Identification of differentially expressed genes in trabecular bone from the iliac crest of osteoarthritic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Etiopathogenesis of Osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Transcriptome analysis reveals specific changes in osteoarthritis synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2013.4

Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA

21 January 2018

1 reference

12 December 2020

Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues

1 reference

12 December 2020

Gene expression analysis reveals HBP1 as a key target for the osteoarthritis susceptibility locus that maps to chromosome 7q22

1 reference

12 December 2020

Genetic risk load and age at symptom onset of knee osteoarthritis

1 reference

12 December 2020

A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility

1 reference

12 December 2020

The CALM1 core promoter polymorphism is not associated with hip osteoarthritis in a United Kingdom Caucasian population

1 reference

12 December 2020

Fibulin 3 peptides Fib3-1 and Fib3-2 are potential biomarkers of osteoarthritis

1 reference

12 December 2020

Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism

1 reference

12 December 2020

A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese

1 reference

12 December 2020

Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility

1 reference

12 December 2020

GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes

1 reference

12 December 2020

From expression QTLs to personalized transcriptomics

1 reference

12 December 2020

Management of osteoarthritis of the knee

1 reference

12 December 2020

Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus

1 reference

12 December 2020

An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage

1 reference

12 December 2020

Identifiers

DOI

10.1017/ERM.2013.4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414786%20AND%20SRC:MED&resulttype=core&format=json