Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice (Q26862954)

J. E. Henley

2

1 reference

C. M. Exline

3

1 reference

O. Mulhern

4

1 reference

E. Lopez

5

1 reference

P. M. Cannon

6

1 reference

language of work or name

1 reference

November 2013

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Journal of Infectious Diseases

published in

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volume

208 Suppl 2

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page(s)

S160-4

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Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice

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CCR5 deficiency increases risk of symptomatic West Nile virus infection

21 March 2017

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New generation humanized mice for virus research: comparative aspects and future prospects

21 March 2017

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Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation

21 March 2017

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 March 2017

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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

21 March 2017

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Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

7 April 2017

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Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

7 April 2017

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

7 April 2017

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Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient

7 April 2017

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Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases

28 September 2017

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Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

28 September 2017

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HIV-1 immunopathogenesis in humanized mouse models

28 September 2017

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Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.

28 September 2017

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The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment

28 September 2017

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An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice

28 September 2017

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Chemokine receptor 5 knockout strategies

28 September 2017

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Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

28 September 2017

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Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody

28 September 2017

1 reference

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A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model

28 September 2017

1 reference

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Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis

28 September 2017

1 reference

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Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient mice

28 September 2017

1 reference

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Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

28 September 2017

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Cytokines and T-cell homeostasis

28 September 2017

1 reference

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Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice

28 September 2017

1 reference

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Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses

28 September 2017

1 reference

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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

28 September 2017

1 reference

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A preclinical xenotransplantation animal model to assess human hematopoietic stem cell engraftment

28 September 2017

1 reference

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CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

28 September 2017

1 reference

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NOD/SCID repopulating cells contribute only to short-term repopulation in the baboon

28 September 2017

1 reference

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Distinct hematopoietic stem/progenitor cell populations are responsible for repopulating NOD/SCID mice compared with nonhuman primates

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24151324

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In vivo engraftment potential of clinical hematopoietic grafts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24151324

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/24151324