Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector. (Q35943417)

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English	Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.	scientific article

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25 January 2020

Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector (English)

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25 January 2020

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25 January 2020

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Jon E Walker

1

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25 January 2020

Rachel X Chen

2

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25 January 2020

Jeannine McGee

3

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25 January 2020

Catherine Nacey

4

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25 January 2020

Richard B Pollard

5

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25 January 2020

Mehrdad Abedi

6

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25 January 2020

Gerhard Bauer

7

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25 January 2020

Joseph S Anderson

9

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7 March 2012

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25 January 2020

Journal of Virology

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25 January 2020

86

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25 January 2020

5719-5729

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25 January 2020

The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment

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2 October 2017

HIV-1 integrase inhibitor resistance and its clinical implications

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Primary resistance to maraviroc in a large set of R5-V3 viral sequences from HIV-1-infected patients

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Clinical syndromes and consequences of antiretroviral-related hepatotoxicity

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Impact of mitochondrial toxicity of HIV-1 antiretroviral drugs on lipodystrophy and metabolic dysregulation

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2 October 2017

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

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Preintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy

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Transplantation of selected or transgenic blood stem cells - a future treatment for HIV/AIDS?

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2 October 2017

Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

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Novel humanized murine models for HIV research

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Stable reduction of CCR5 by RNAi through hematopoietic stem cell transplant in non-human primates

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2 October 2017

Complete knockdown of CCR5 by lentiviral vector-expressed siRNAs and protection of transgenic macrophages against HIV-1 infection

1 reference

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2 October 2017

Current status of gene therapy strategies to treat HIV/AIDS.

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2 October 2017

Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain

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The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

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2 October 2017

A nucleolar TAR decoy inhibitor of HIV-1 replication.

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2 October 2017

siRNA-directed inhibition of HIV-1 infection

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2 October 2017

A combination anti-HIV-1 gene therapy approach using a single transcription unit that expresses antisense, decoy, and sense RNAs, and trans-dominant negative mutant Gag and Env proteins

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Antiretroviral resistance during successful therapy of HIV type 1 infection.

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Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

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Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells

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24 September 2018

Human immunodeficiency virus type 1 restriction by human-rhesus chimeric tripartite motif 5alpha (TRIM 5alpha) in CD34(+) cell-derived macrophages in vitro and in T cells in vivo in severe combined immunodeficient (SCID-hu) mice transplanted with hu

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1 reference

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1 reference

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Allogeneic transplantation of CCR5-deficient progenitor cells in a patient with HIV infection: an update after 3 years and the search for patient no. 2

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12 December 2020

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