Permeation, selectivity and gating in store-operated CRAC channels (Q26864181)

Crossref

Murali Prakriya

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

1 September 2012

1 reference

published in

Journal of Physiology

1 reference

volume

590

1 reference

issue

17

1 reference

page(s)

4179-91

1 reference

Store-independent activation of Orai1 by SPCA2 in mammary tumors

cites work

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A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells

21 March 2017

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STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

21 March 2017

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Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

21 March 2017

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Orai1 is an essential pore subunit of the CRAC channel

21 March 2017

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Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

21 March 2017

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Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

21 March 2017

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Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

21 March 2017

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CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

21 March 2017

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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

21 March 2017

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STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

21 March 2017

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Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)

21 March 2017

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Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry

21 March 2017

1 reference

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Structure and gating mechanism of the acetylcholine receptor pore

21 March 2017

1 reference

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STIM1 gates the store-operated calcium channel ORAI1 in vitro

21 March 2017

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Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation

21 March 2017

1 reference

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Stored Ca2+ depletion-induced oligomerization of stromal interaction molecule 1 (STIM1) via the EF-SAM region: An initiation mechanism for capacitive Ca2+ entry

21 March 2017

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A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

21 March 2017

1 reference

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Potentiation and inhibition of Ca(2+) release-activated Ca(2+) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP(3) receptors

21 March 2017

1 reference

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Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel

21 March 2017

1 reference

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Store-operated Ca2+ entry in sensory neurons: functional role and the effect of painful nerve injury

21 March 2017

1 reference

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Store-operated calcium channels

21 March 2017

1 reference

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CRACM/Orai ion channel expression and function in human lung mast cells

7 April 2017

1 reference

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Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Gated regulation of CRAC channel ion selectivity by STIM1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Store-operated calcium channels: new perspectives on mechanism and function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Stoichiometric requirements for trapping and gating of Ca2+ release-activated Ca2+ (CRAC) channels by stromal interaction molecule 1 (STIM1).

28 September 2017

1 reference

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Temperature-dependent STIM1 activation induces Ca²+ influx and modulates gene expression

28 September 2017

1 reference

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Competitive modulation of Ca2+ release-activated Ca2+ channel gating by STIM1 and 2-aminoethyldiphenyl borate

28 September 2017

1 reference

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A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits

28 September 2017

1 reference

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S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.

28 September 2017

1 reference

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Molecular basis of calcium signaling in lymphocytes: STIM and ORAI

28 September 2017

1 reference

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Pore architecture of the ORAI1 store-operated calcium channel.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Structural determinants of ion permeation in CRAC channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Molecular determinants of fast Ca2+-dependent inactivation and gating of the Orai channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

A Ca2(+ )release-activated Ca2(+) (CRAC) modulatory domain (CMD) within STIM1 mediates fast Ca2(+)-dependent inactivation of ORAI1 channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Checking your SOCCs and feet: the molecular mechanisms of Ca2+ entry in skeletal muscle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Properties of Orai1 mediated store-operated current depend on the expression levels of STIM1 and Orai1 proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Functional stoichiometry of the unitary calcium-release-activated calcium channel

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Complex actions of 2-aminoethyldiphenyl borate on store-operated calcium entry

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Store-dependent and -independent modes regulating Ca2+ release-activated Ca2+ channel activity of human Orai1 and Orai3

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Gating at the selectivity filter in cyclic nucleotide-gated channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Orai1 subunit stoichiometry of the mammalian CRAC channel pore.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Orai1 mutations alter ion permeation and Ca2+-dependent fast inactivation of CRAC channels: evidence for coupling of permeation and gating

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.

28 September 2017

1 reference

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Molecular evolution and structural analysis of the Ca(2+) release-activated Ca(2+) channel subunit, Orai

28 September 2017

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The molecular choreography of a store-operated calcium channel

28 September 2017

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CRACM1 multimers form the ion-selective pore of the CRAC channel.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Regulation of CRAC channel activity by recruitment of silent channels to a high open-probability gating mode

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity.

28 September 2017

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Functional architecture of the inner pore of a voltage-gated Ca2+ channel

28 September 2017

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Molecular insights into ion channel function (Review).

28 September 2017

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Fast Ca(2+)-dependent inactivation of the store-operated Ca2+ current (ISOC) in liver cells: a role for calmodulin.

28 September 2017

1 reference

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Ca2+ modulation of Ca2+ release-activated Ca2+ channels is responsible for the inactivation of its monovalent cation current

28 September 2017

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A store-operated calcium channel in Drosophila S2 cells

28 September 2017

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Permeation and selectivity in calcium channels.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

2-aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Separation and characterization of currents through store-operated CRAC channels and Mg2+-inhibited cation (MIC) channels

28 September 2017

1 reference

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Monovalent cation permeability and Ca(2+) block of the store-operated Ca(2+) current I(CRAC )in rat basophilic leukemia cells

28 September 2017

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Modification of store-operated channel coupling and inositol trisphosphate receptor function by 2-aminoethoxydiphenyl borate in DT40 lymphocytes

28 September 2017

1 reference

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Flexibility of the Kir6.2 inward rectifier K(+) channel pore

28 September 2017

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The moving parts of voltage-gated ion channels

28 September 2017

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Conductance and permeation of monovalent cations through depletion-activated Ca2+ channels (ICRAC) in Jurkat T cells

28 September 2017

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Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedback

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Blockade of current through single calcium channels by Cd2+, Mg2+, and Ca2+. Voltage and concentration dependence of calcium entry into the pore

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

'Quantal' Ca2+ release and the control of Ca2+ entry by inositol phosphates--a possible mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Submicromolar La3+ concentrations block the calcium release-activated channel, and impair CD69 and CD25 expression in CD3- or thapsigargin-activated Jurkat cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3473277

Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2.

28 September 2017

1 reference

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Calcium release-activated calcium current in rat mast cells

28 November 2018

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12 December 2020

Gated access to the pore of a voltage-dependent K+ channel

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12 December 2020

Substituted-cysteine accessibility method

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12 December 2020

The role of intracellular Ca2+ in the regulation of the plasma membrane Ca2+ permeability of unstimulated rat lymphocytes

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12 December 2020