Optimizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cysteine cathepsins (Q26866319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22901826%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Optimizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cysteine cathepsins (English)

2 references

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11 February 2020

1

1 reference

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11 February 2020

Lorenzo Breschi

3

1 reference

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11 February 2020

Ivarne L.S. Tersariol

5

1 reference

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11 February 2020

Arzu Tezvergil-Mutluay

7

1 reference

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11 February 2020

author name string

Annalisa Mazzoni

4

2 references

Crossref

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11 February 2020

Saulo Geraldeli

6

2 references

Crossref

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11 February 2020

Fabio D Nascimento

2

1 reference

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11 February 2020

Marcela R Carrilho

8

1 reference

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11 February 2020

Ricardo M Carvalho

9

1 reference

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11 February 2020

Franklin R Tay

10

1 reference

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11 February 2020

David H Pashley

11

1 reference

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11 February 2020

language of work or name

1 reference

16 August 2012

1 reference

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11 February 2020

2 references

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11 February 2020

volume

29

2 references

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11 February 2020

issue

1

2 references

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11 February 2020

page(s)

116-135

1 reference

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Cysteine cathepsins: from structure, function and regulation to new frontiers

11 February 2020

cites work

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Regulation of reactionary dentin formation by odontoblasts in response to polymicrobial invasion of dentin matrix.

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Carbodiimide cross-linking inactivates soluble and matrix-bound MMPs, in vitro

28 September 2017

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Increased matrix metalloproteinase-2 and bone sialoprotein response to human coronal caries

28 September 2017

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Cysteine cathepsins in human carious dentin

28 September 2017

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Effect of dentin etching and chlorhexidine application on metalloproteinase-mediated collagen degradation

28 September 2017

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Immunohistochemical and biochemical assay of MMP-3 in human dentine

28 September 2017

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The inhibitory effects of quaternary ammonium methacrylates on soluble and matrix-bound MMPs

28 September 2017

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State of the art etch-and-rinse adhesives.

28 September 2017

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28 September 2017

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28 September 2017

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The requirement of zinc and calcium ions for functional MMP activity in demineralized dentin matrices.

28 September 2017

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Osteoclasts and odontoclasts: signaling pathways to development and disease

28 September 2017

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The inhibitory effect of polyvinylphosphonic acid on functional matrix metalloproteinase activities in human demineralized dentin.

28 September 2017

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An all-in-one adhesive does not etch beyond hybrid layers

28 September 2017

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A review--micromorphological evidence of degradation in resin-dentin bonds and potential preventional solutions

28 September 2017

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Effects of residual ethanol on the rate and degree of conversion of five experimental resins

28 September 2017

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The effect of stromelysin-1 (MMP-3) on non-collagenous extracellular matrix proteins of demineralized dentin and the adhesive properties of restorative resins

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Dental adhesion review: aging and stability of the bonded interface.

28 September 2017

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From dry bonding to water-wet bonding to ethanol-wet bonding. A review of the interactions between dentin matrix and solvated resins using a macromodel of the hybrid layer.

28 September 2017

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The role of matrix metalloproteinases in the oral environment

28 September 2017

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Chlorhexidine preserves dentin bond in vitro

28 September 2017

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28 September 2017

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28 September 2017

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Collagenase unwinds triple-helical collagen prior to peptide bond hydrolysis

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate

28 September 2017

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Acid attack and cathepsin K in bone resorption around total hip replacement prosthesis

28 September 2017

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Collagen structure and functional implications

28 September 2017

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28 September 2017

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Long-term durability of dentin bonds made with a self-etching primer, in vivo

28 September 2017

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Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

28 September 2017

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The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions

28 September 2017

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The biogenesis of lysosomes: is it a kiss and run, continuous fusion and fission process?

28 September 2017

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Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts

28 September 2017

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Structurally Distinct Collagen Types

28 September 2017

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Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins.

28 September 2017

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MMP activity in the hybrid layer detected with in situ zymography

28 September 2017

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Chlorhexidine stabilizes the adhesive interface: a 2-year in vitro study

31 May 2018

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Host-derived loss of dentin matrix stiffness associated with solubilization of collagen

31 May 2018

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Autocatalytic processing of recombinant human procathepsin B is a bimolecular process.

31 May 2018

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A novel organ culture method to study the function of human odontoblasts in vitro: gelatinase expression by odontoblasts is differentially regulated by TGF-beta1.

31 May 2018

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Major increase in endopeptidase activity of human cathepsin B upon removal of occluding loop contacts.

31 May 2018

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Activation mechanisms of matrix metalloproteinases.

31 May 2018

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Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene.

31 May 2018

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Multi-step processing of procathepsin L in vitro

31 May 2018

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Action of rat liver cathepsin L on collagen and other substrates

31 May 2018

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Cathepsin B1. A lysosomal enzyme that degrades native collagen

31 May 2018

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Dissociation of ionizing groups in the binding cleft inversely controls the endo- and exopeptidase activities of cathepsin B.

31 May 2018

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A latent Mr 94,000 gelatin-degrading metalloprotease induced during differentiation of HL-60 promyelocytic leukemia cells: a member of the collagenase family of enzymes.

31 May 2018

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A model to explain the pH-dependent specificity of cathepsin B-catalysed hydrolyses

31 May 2018

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Identification of an abundant latent 94-kDa gelatin-degrading metalloprotease in human saliva which is activated by acid exposure: implications for a role in digestion of collagenous proteins.

31 May 2018

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Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues

31 May 2018

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Physiological mechanisms for metalloproteinase activation

31 May 2018

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MMP-2 assay within the hybrid layer created by a two-step etch-and-rinse adhesive: biochemical and immunohistochemical analysis

31 May 2018

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Enzymatic degradation of adhesive-dentin interfaces produced by mild self-etch adhesives

28 November 2018

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Effect of iron on matrix metalloproteinase inhibition and on the prevention of dentine erosion

28 November 2018

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Differential expression of matrix metalloproteinase-2 in human coronal and radicular sound and carious dentine.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Gels containing MMP inhibitors prevent dental erosion in situ.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Cysteine cathepsins in human dentin-pulp complex.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Inhibition of enzymatic degradation of adhesive-dentin interfaces

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Determination of matrix metalloproteinases in human radicular dentin.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

The type II collagen fragments Helix-II and CTX-II reveal different enzymatic pathways of human cartilage collagen degradation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Immunohistochemical identification of MMP-2 and MMP-9 in human dentin: correlative FEI-SEM/TEM analysis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

The size exclusion characteristics of type I collagen: implications for the role of noncollagenous bone constituents in mineralization

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

In vivo preservation of the hybrid layer by chlorhexidine.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Zymographic analysis and characterization of MMP-2 and -9 forms in human sound dentin

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Characterization of the mechanisms by which gelatinase A, neutrophil collagenase, and membrane-type metalloproteinase MMP-14 recognize collagen I and enzymatically process the two alpha-chains.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Matrix metalloproteinase-8 (MMP-8) is the major collagenase in human dentin.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Reactivation of inactivated endogenous proteolytic activities in phosphoric acid-etched dentine by etch-and-rinse adhesives

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Collagen degradation by interleukin-1beta-stimulated gingival fibroblasts is accompanied by release and activation of multiple matrix metalloproteinases and cysteine proteinases

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

The upregulation of matrix metalloproteinase-9 in inflamed human dental pulps.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Analysis of gene and protein expression in healthy and carious tooth pulp with cDNA microarray and two-dimensional gel electrophoresis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Chlorhexidine arrests subclinical degradation of dentin hybrid layers in vivo

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Cathepsin X binds to cell surface heparan sulfate proteoglycans

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Matrix metalloproteinase-13 (MMP-13, collagenase-3) is highly expressed in human tooth pulp.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Resin-dentin interfacial ultrastructure and microtensile dentin bond strength after five-year water storage.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

(Pre-)osteoclasts induce retraction of osteoblasts before their fusion to osteoclasts.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Comprehensive search for cysteine cathepsins in the human genome

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Collagen degradation by host-derived enzymes during aging

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Regulation of collagenase activities of human cathepsins by glycosaminoglycans

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Procongopain from Trypanosoma congolense is processed at basic pH: an unusual feature among cathepsin L-like cysteine proteases.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Matrix metalloproteinase levels and gelatinolytic activity in clinically healthy and inflamed human dental pulps.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Expression profile of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in mature human odontoblasts and pulp tissue.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

In vivo long-term durability of the bond to dentin using two adhesive systems.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

In situ atomic force microscopy of partially demineralized human dentin collagen fibrils

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Adhesive phase separation at the dentin interface under wet bonding conditions

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Collagen-ligand interaction in dentinal adhesion: computer visualization and analysis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

The effects of MMP inhibitors on human salivary MMP activity and caries progression in rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Cathepsin B activity regulation. Heparin-like glycosaminogylcans protect human cathepsin B from alkaline pH-induced inactivation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

The matrix metalloproteinase gelatinase A in human dentine

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

The structure of interfibrillar proteoglycan bridges (shape modules') in extracellular matrix of fibrous connective tissues and their stability in various chemical environments.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Folding and activation of human procathepsin S from inclusion bodies produced in Escherichia coli.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Maturation of human procathepsin B. Proenzyme activation and proteolytic processing of the precursor to the mature proteinase, in vitro, are primarily unimolecular processes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684081

Localization of MMP-2, MMP-9, TIMP-1, and TIMP-2 in human coronal dentine

28 November 2018

1 reference

12 December 2020

The overwet phenomenon: a transmission electron microscopic study of surface moisture in the acid-conditioned, resin-dentin interface

1 reference

12 December 2020

The overwet phenomenon: an optical, micromorphological study of surface moisture in the acid-conditioned, resin-dentin interface

1 reference

12 December 2020

Micromorphological spectrum from overdrying to overwetting acid-conditioned dentin in water-free acetone-based, single-bottle primer/adhesives

1 reference

12 December 2020

A TEM study of two water-based adhesive systems bonded to dry and wet dentin

1 reference

12 December 2020

Is cathepsin K truly involved in bone resorption?

1 reference

12 December 2020

The collagenolytic activity of cathepsin K is unique among mammalian proteinases

1 reference

12 December 2020

The effect of MMP inhibitor metastat on fissure caries progression in rats

1 reference

12 December 2020

Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases

1 reference

12 December 2020

THE MACROMOLECULAR ORGANIZATION OF DENTINE MATRIX COLLAGEN. I. CHARACTERIZATION OF DENTINE COLLAGEN

1 reference

12 December 2020

The influence of a matrix metalloproteinase on the remineralization of artificially demineralized dentin

1 reference

12 December 2020

Activation of gelatinolytic/collagenolytic activity in dentin by self-etching adhesives

1 reference

12 December 2020

Localization of cathepsin D in human odontoclasts. a light and electron microscopical immunocytochemical study

1 reference

12 December 2020

Durability of resin-dentin bonds

1 reference

12 December 2020

Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium

1 reference

12 December 2020

Tissue levels of matrix metalloproteinases in pulps and periapical lesions

1 reference

12 December 2020

The localization of matrix metalloproteinase-20 (MMP-20, enamelysin) in mature human teeth

1 reference

12 December 2020

Water treeing--a potential mechanism for degradation of dentin adhesives

1 reference

12 December 2020

SEM and TEM analysis of water degradation of human dentinal collagen

1 reference

12 December 2020

Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation

1 reference

12 December 2020

A preliminary study of activation of collagenase in carious human dentine matrix

1 reference

12 December 2020

Porcine spleen cathepsin B is an exopeptidase

1 reference

12 December 2020

Biosynthesis of cathepsin B in cultured normal and I-cell fibroblasts

1 reference

12 December 2020

Chromophoric and fluorophoric peptide substrates cleaved through the dipeptidyl carboxypeptidase activity of cathepsin B

1 reference

12 December 2020

Effect of lactic acid and proteolytic enzymes on the release of organic matrix components from human root dentin

1 reference

12 December 2020

Correlative transmission electron microscopy examination of nondemineralized and demineralized resin-dentin interfaces formed by two dentin adhesive systems

1 reference

12 December 2020

Immunohistochemical localization of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in human carious dentine

1 reference

12 December 2020

Localization of matrix metalloproteinases (MMPs-2, 8, 9 and 20) in normal and carious dentine

1 reference

12 December 2020

A first study on the usefulness of matrix metalloproteinase 9 from dentinal fluid to indicate pulp inflammation

1 reference

12 December 2020

Technique sensitivity in bonding to vital, acid-etched dentin

1 reference

12 December 2020

Matrix metalloproteinase-2 expression induced by two different adhesive systems on human pulp fibroblasts

1 reference

12 December 2020

What causes durability reduction in tooth-colored resin restorations?

1 reference

12 December 2020

MMP-3 provokes CTGF/CCN2 production independently of protease activity and dependently on dynamin-related endocytosis, which contributes to human dental pulp cell migration

1 reference

12 December 2020

Durability of Enamel Bonding Using Two-step Self-etch Systems on Ground and Unground Enamel

1 reference

12 December 2020

Self-etching increases matrix metalloproteinase expression in the dentin-pulp complex

1 reference

12 December 2020

The expression of MMP-8 in human odontoblasts and dental pulp cells is down-regulated by TGF-beta1.

1 reference

12 December 2020

Effect of proteinase inhibitors on intracellular processing of cathepsin B, H and L in rat macrophages

1 reference

12 December 2020

Comparative SEM and TEM examination of the ultrastructure of the resin-dentin interdiffusion zone

1 reference

12 December 2020

Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Evidence for two converging pathways of chondrocyte-mediated proteoglycan degradation

1 reference

12 December 2020

Latency of cathepsin B secreted by human colon carcinoma cells is not linked to secretion of cystatin C and is relieved by neutrophil elastase

1 reference

12 December 2020

Identification of tissue inhibitor of metalloproteinases-1 (TIMP-1) in human teeth and its distribution in cementum and dentine

1 reference

12 December 2020

Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption

1 reference

12 December 2020

Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins

1 reference

12 December 2020

Self-Etching Adhesives Increase Collagenolytic Activity in Radicular Dentin

1 reference

12 December 2020

10.1016/J.DENTAL.2012.08.004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22901826%20AND%20SRC:MED&resulttype=core&format=json

release_ibbhtrlt2rgppdcd7becabl4mq

11 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ibbhtrlt2rgppdcd7becabl4mq

24 November 2022

mapped directly with Wikidata item

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22901826%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22901826%20AND%20SRC:MED&resulttype=core&format=json