Targeting Toll-like receptors with small molecule agents (Q26992220)

Hang Yin

series ordinal

3

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language of work or name

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21 June 2013

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published in

Chemical Society Reviews

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volume

42

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issue

12

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page(s)

4859-66

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Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

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Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals

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Development of β-amino alcohol derivatives that inhibit Toll-like receptor 4 mediated inflammatory response as potential antiseptics

28 September 2017

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Structural biology of the Toll-like receptor family

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Eritoran tetrasodium (E5564) treatment for sepsis: review of preclinical and clinical studies

28 September 2017

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Application of a novel in silico high-throughput screen to identify selective inhibitors for protein-protein interactions

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Toll-like receptor 4 in CNS pathologies

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Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides

28 September 2017

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Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

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28 September 2017

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A novel cyclohexene derivative, ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), selectively inhibits toll-like receptor 4-mediated cytokine production through suppression of intracellular signaling

28 September 2017

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28 September 2017

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28 September 2017

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Taking toll: lipid A mimetics as adjuvants and immunomodulators

28 September 2017

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Structure-activity relationships in human Toll-like receptor 2-specific monoacyl lipopeptides.

28 September 2017

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Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product

31 May 2018

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TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain

31 May 2018

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TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules

21 January 2018

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A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis

21 January 2018

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Characterization of heme as activator of Toll-like receptor 4.

21 January 2018

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Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward.

21 January 2018

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Structure-activity relationship of synthetic toll-like receptor 4 agonists

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23503527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toll-like receptor 2 antagonists. Part 1: preliminary SAR investigation of novel synthetic phospholipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/23503527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

0 references

1 reference

PubMed publication ID

23503527

1 reference