A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease (Q26997058)

S. Rivest

series ordinal

2

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language of work or name

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October 2013

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Journal of Molecular Cell Biology

published in

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volume

5

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issue

5

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page(s)

284-93

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CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

cites work

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Blood monocytes: development, heterogeneity, and relationship with dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

GM-CSF upregulated in rheumatoid arthritis reverses cognitive impairment and amyloidosis in Alzheimer mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

The many roles of chemokines and chemokine receptors in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

The origin and differentiation of microglial cells during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Monocyte chemoattractant protein-1 (MCP-1): an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factoralpha signaling during peripheral organ inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Innate immunity and the etiology of late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

CD36 mediates the innate host response to beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

CCR2 mediates homeostatic and inflammatory release of Gr1(high) monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Neuroinflammation: a common pathway in CNS diseases as mediated at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Serum MCP-1 levels are increased in mild cognitive impairment and mild Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Blood monocytes: distinct subsets, how they relate to dendritic cells, and their possible roles in the regulation of T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Blood monocytes consist of two principal subsets with distinct migratory properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Functional diversity of microglia - how heterogeneous are they to begin with?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Proteins in microglial activation--inputs and outputs by subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Granulocyte Colony-Stimulating Factor Attenuates Chronic Neuroinflammation in the Brain of Amyloid Precursor Protein Transgenic Mice: An Alzheimer's Disease Mouse Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Innate immunity in the CNS: redefining the relationship between the CNS and Its environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Stem cell factor and granulocyte colony-stimulating factor reduce β-amyloid deposits in the brains of APP/PS1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy and Alzheimer's Disease (AD) individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Chemokines--chemotactic cytokines that mediate inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Immunophenotypes in the circulation of patients with mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

The importance of inflammatory mechanisms in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Microglial overexpression of the M-CSF receptor augments phagocytosis of opsonized Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Macrophage colony stimulating factor promotes phagocytosis by murine microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

The many faces of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

The role of microglial cell subsets in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Hematopoietic CC-chemokine receptor 2 (CCR2) competent cells are protective for the cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Impaired functions of peripheral blood monocyte subpopulations in aged humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Immune profiling of Alzheimer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Macrophages and microglia in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

CCL2 disrupts the adherens junction: implications for neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Microglial phenotype: is the commitment reversible?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Alzheimer's disease is a synaptic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Neuroprotective properties of the innate immune system and bone marrow stem cells in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Inflammatory monocytes activate memory CD8(+) T and innate NK lymphocytes independent of cognate antigen during microbial pathogen invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Bone-marrow-derived microglia: myth or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

G-CSF rescues the memory impairment of animal models of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta) production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Systemic immune system alterations in early stages of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028

Nomenclature of monocytes and dendritic cells in blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT028