The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation (Q26999027)

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English	The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation	scientific article

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scholarly article

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5 references

12 October 2019

11 December 2019

19 December 2019

20 December 2019

22 December 2019

The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation (English)

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12 October 2019

DNA-binding protein

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11 December 2019

nuclear protein

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19 December 2019

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20 December 2019

transcription factor

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22 December 2019

2

object named as

Kathrin Plath

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author name string

Ryan Schmidt

1

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language of work or name

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publication date

22 October 2012

6 references

12 October 2019

11 December 2019

19 December 2019

20 December 2019

22 December 2019

6 references

12 October 2019

11 December 2019

19 December 2019

20 December 2019

22 December 2019

13

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251

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A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells

1 reference

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21 March 2017

Histone H3K27ac separates active from poised enhancers and predicts developmental state

1 reference

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21 March 2017

c-Myc regulates transcriptional pause release

1 reference

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21 March 2017

Direct cell reprogramming is a stochastic process amenable to acceleration

1 reference

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21 March 2017

Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers

1 reference

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21 March 2017

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

1 reference

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21 March 2017

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

1 reference

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21 March 2017

The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation

1 reference

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21 March 2017

Induced pluripotent stem cell lines derived from human somatic cells

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21 March 2017

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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21 March 2017

Embryonic stem cell lines derived from human blastocysts

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21 March 2017

Establishment in culture of pluripotential cells from mouse embryos

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21 March 2017

Generation of germline-competent induced pluripotent stem cells

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21 March 2017

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

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21 March 2017

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

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21 March 2017

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease

1 reference

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21 March 2017

An Oct4-centered protein interaction network in embryonic stem cells

1 reference

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21 March 2017

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

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21 March 2017

An extended transcriptional network for pluripotency of embryonic stem cells

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21 March 2017

A protein interaction network for pluripotency of embryonic stem cells

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21 March 2017

Control of developmental regulators by Polycomb in human embryonic stem cells

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21 March 2017

Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3

1 reference

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21 March 2017

Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network

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21 March 2017

Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog

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21 March 2017

Dissecting self-renewal in stem cells with RNA interference

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21 March 2017

New type of POU domain in germ line-specific protein Oct-4

1 reference

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21 March 2017

Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains

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21 March 2017

Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells

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21 March 2017

Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

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7 April 2017

Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency

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7 April 2017

A unique chromatin signature uncovers early developmental enhancers in humans

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7 April 2017

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

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7 April 2017

The Ink4/Arf locus is a barrier for iPS cell reprogramming

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7 April 2017

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

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7 April 2017

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

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7 April 2017

Dissecting direct reprogramming through integrative genomic analysis

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7 April 2017

Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

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7 April 2017

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

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7 April 2017

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

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7 April 2017

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

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28 September 2017

Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming

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28 September 2017

Efficient iPS cell production with the MyoD transactivation domain in serum-free culture

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28 September 2017

The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells

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28 September 2017

Chromatin-modifying enzymes as modulators of reprogramming

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491406

28 September 2017

Polycomb-repressed genes have permissive enhancers that initiate reprogramming

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28 September 2017

Induced pluripotent stem cells--opportunities for disease modelling and drug discovery

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28 September 2017

OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes

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28 September 2017

Radical acceleration of nuclear reprogramming by chromatin remodeling with the transactivation domain of MyoD.

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28 September 2017

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1.

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28 September 2017

Methods for making induced pluripotent stem cells: reprogramming à la carte

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Reprogramming factor expression initiates widespread targeted chromatin remodeling

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28 September 2017

Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions

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28 September 2017

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

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28 September 2017

Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate.

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28 September 2017

Promotion of direct reprogramming by transformation-deficient Myc.

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28 September 2017

Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming

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28 September 2017

A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

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28 September 2017

A small ubiquitin-related modifier-interacting motif functions as the transcriptional activation domain of Krüppel-like factor 4.

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28 September 2017

Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming

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28 September 2017

Global chromatin architecture reflects pluripotency and lineage commitment in the early mouse embryo

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28 September 2017

Dynamic single-cell imaging of direct reprogramming reveals an early specifying event

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28 September 2017

Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis

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28 September 2017

A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

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28 September 2017

Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc

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28 September 2017

Nanog is the gateway to the pluripotent ground state.

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28 September 2017

Senescence impairs successful reprogramming to pluripotent stem cells

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28 September 2017

Adult mice generated from induced pluripotent stem cells

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28 September 2017

iPS cells produce viable mice through tetraploid complementation

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28 September 2017

iPS cells can support full-term development of tetraploid blastocyst-complemented embryos

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28 September 2017

Chd1 regulates open chromatin and pluripotency of embryonic stem cells

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28 September 2017

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

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28 September 2017

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency

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28 September 2017

Post-translational regulation of Oct4 transcriptional activity

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28 September 2017

Role of the murine reprogramming factors in the induction of pluripotency

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28 September 2017

Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds

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28 September 2017

Global transcription in pluripotent embryonic stem cells.

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28 September 2017

Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse

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28 September 2017

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

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28 September 2017

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

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28 September 2017

Cell cycle control of embryonic stem cells

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28 September 2017

Protecting genomic integrity in somatic cells and embryonic stem cells

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28 September 2017

Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells

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28 September 2017

Sexually mature individuals of Xenopus laevis from the transplantation of single somatic nuclei

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28 September 2017

Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer

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28 September 2017

Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites

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28 September 2017

De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells

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28 September 2017

The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.

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31 May 2018

Global epigenetic changes during somatic cell reprogramming to iPS cells

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31 May 2018

Reprogramming of mouse and human somatic cells by high-performance engineered factors.

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31 May 2018

Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.

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31 May 2018

Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b

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31 May 2018

c-Myc is dispensable for direct reprogramming of mouse fibroblasts.

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21 January 2018

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts

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21 January 2018

Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb.

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https://api.crossref.org/works/10.1186%2FGB-2012-13-10-251

21 January 2018

Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency

1 reference

https://api.crossref.org/works/10.1186%2FGB-2012-13-10-251

21 January 2018

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

1 reference

https://api.crossref.org/works/10.1186%2FGB-2012-13-10-251

21 January 2018

Spatially precise DNA bending is an essential activity of the sox2 transcription factor

1 reference

https://api.crossref.org/works/10.1186%2FGB-2012-13-10-251

21 January 2018

A core Klf circuitry regulates self-renewal of embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1186%2FGB-2012-13-10-251

21 January 2018

O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network

1 reference

https://api.crossref.org/works/10.1186%2FGB-2012-13-10-251

21 January 2018

The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells

1 reference

https://api.crossref.org/works/10.1186%2FGB-2012-13-10-251

21 January 2018

Conversion of Sox17 into a pluripotency reprogramming factor by reengineering its association with Oct4 on DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/23088445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A hierarchical network controls protein translation during murine embryonic stem cell self-renewal and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23088445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/GB-2012-13-10-251

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Dimensions Publication ID

0 references

release_dfezefyrqbhgddvitgrdoya6me

1 reference

https://api.fatcat.wiki/v0/release/dfezefyrqbhgddvitgrdoya6me

24 November 2022

based on heuristic

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

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