Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells (Q28176681)

GOA release 2020-03-11

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Susan Tweedie

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Ian Chambers

object named as

Ian Chambers

1

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author name string

Douglas Colby

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Morag Robertson

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Jennifer Nichols

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Sonia Lee

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Austin Smith

Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation.

7

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language of work or name

English

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publication date

30 May 2003

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published in

Cell

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volume

113

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issue

5

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page(s)

643-55

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cites work

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7 January 2021

Multipotent cell lineages in early mouse development depend on SOX2 function

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The origin and efficient derivation of embryonic stem cells in the mouse

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Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells.

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7 January 2021

Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

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7 January 2021

Structure of the mouse leukaemia inhibitory factor receptor gene: regulated expression of mRNA encoding a soluble receptor isoform from an alternative 5' untranslated region.

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7 January 2021

Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway

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7 January 2021

A synthetic inhibitor of the mitogen-activated protein kinase cascade

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7 January 2021

Establishment in culture of pluripotential cells from mouse embryos

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7 January 2021

Mouse germline restriction of Oct4 expression by germ cell nuclear factor

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7 January 2021

Two conserved sequence blocks within eukaryotic tRNA genes are major promoter elements

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7 January 2021

Maintenance of an extrachromosomal plasmid vector in mouse embryonic stem cells

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7 January 2021

Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo

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7 January 2021

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

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7 January 2021

A stem cell molecular signature

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7 January 2021

Pluripotency of mesenchymal stem cells derived from adult marrow

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7 January 2021

Essential function of LIF receptor in motor neurons

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7 January 2021

Generation of purified neural precursors from embryonic stem cells by lineage selection

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7 January 2021

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

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7 January 2021

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

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7 January 2021

Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture

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7 January 2021

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

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7 January 2021

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

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7 January 2021

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

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7 January 2021

Molecular mechanism to maintain stem cell renewal of ES cells

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7 January 2021

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

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7 January 2021

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

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7 January 2021

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

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7 January 2021

Isolation and characterization of a multipotent clone of human embryonal carcinoma cells.

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Oct-4: gatekeeper in the beginnings of mammalian development.

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7 January 2021

"Stemness": transcriptional profiling of embryonic and adult stem cells

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7 January 2021

Developmentally programmed induction of differentiation inhibiting activity and the control of stem cell populations

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7 January 2021

Long-term proliferation of mouse primordial germ cells in culture

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7 January 2021

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

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7 January 2021

Mouse ubiquitous B2 repeat in polysomal and cytoplasmic poly(A)+RNAs: uniderectional orientation and 3′-end localization

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7 January 2021

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

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7 January 2021

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

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7 January 2021

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

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7 January 2021

Photochemical preparation of a pyridone containing tetracycle: a Jak protein kinase inhibitor

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7 January 2021

Embryonic stem cell lines derived from human blastocysts

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7 January 2021

An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M.

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7 January 2021

A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells.

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7 January 2021

Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways

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7 January 2021

Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders

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7 January 2021