Expanding the clinical indications for α(1)-antitrypsin therapy (Q27000764)

language of work or name

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7 September 2012

1 reference

1 reference

18

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page(s)

957-70

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Creative Commons Attribution 4.0 International

copyright license

start time

16 May 2012

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April 2022 Public Data File from Crossref

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copyrighted

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cites work

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alpha1-antitrypsin and its C-terminal fragment attenuate effects of degranulated neutrophil-conditioned medium on lung cancer HCC cells, in vitro

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Synergistic anticryptosporidial potential of the combination alpha-1-antitrypsin and paromomycin

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Type 2 diabetes as an inflammatory disease

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Sterile inflammation: sensing and reacting to damage

7 April 2017

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α-1 antitrypsin promotes semimature, IL-10-producing and readily migrating tolerogenic dendritic cells

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Sensing necrotic cells

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Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation

28 September 2017

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A review of α1-antitrypsin deficiency

28 September 2017

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Inhibition of IL-32 activation by α-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model

28 September 2017

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Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same?

28 September 2017

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α-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejection

28 September 2017

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Danger signals activating innate immunity in graft-versus-host disease

28 September 2017

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Gene therapy for alpha-1 antitrypsin deficiency

28 September 2017

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N-glycosylation and biological activity of recombinant human alpha1-antitrypsin expressed in a novel human neuronal cell line

28 September 2017

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Acute-phase protein α1-antitrypsin inhibits neutrophil calpain I and induces random migration

28 September 2017

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Efficacy of alpha1-antitrypsin augmentation therapy in conditions other than pulmonary emphysema

28 September 2017

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α(1)-antitrypsin deficiency and inflammation

28 September 2017

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The discovery of α1-antitrypsin and its role in health and disease

28 September 2017

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Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model

28 September 2017

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28 September 2017

Hypoxia and inflammation

1 reference

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An overview of salsalate as a potential antidiabetic therapy

28 September 2017

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Heat shock proteins and high mobility group box 1 protein lack cytokine function

28 September 2017

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Gevokizumab, an anti-IL-1β mAb for the potential treatment of type 1 and 2 diabetes, rheumatoid arthritis and cardiovascular disease

28 September 2017

1 reference

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Lung deposition of inhaled alpha-1-proteinase inhibitor (alpha 1-PI) - problems and experience of alpha1-PI inhalation therapy in patients with hereditary alpha1-PI deficiency and cystic fibrosis

28 September 2017

1 reference

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The paradox of the neutrophil's role in tissue injury

28 September 2017

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Lung disease associated with alpha1-antitrypsin deficiency

28 September 2017

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State-of-the-art: rheumatoid arthritis

28 September 2017

1 reference

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Inflammation in neurological disorders: a help or a hindrance?

28 September 2017

1 reference

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Intravenous alpha-1 antitrypsin augmentation therapy: systematic review.

28 September 2017

1 reference

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Emerging drugs for alpha-1-antitrypsin deficiency

28 September 2017

1 reference

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Alpha-1-antitrypsin deficiency: importance of proteasomal and autophagic degradative pathways in disposal of liver disease-associated protein aggregates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Culture of impure human islet fractions in the presence of alpha-1 antitrypsin prevents insulin cleavage and improves islet recovery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Cholesterol rich lipid raft microdomains are gateway for acute phase protein, SERPINA1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

The paradoxical role of inflammation in cardiac repair and regeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Anti-inflammatory Agents: Present and Future

28 September 2017

1 reference

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Regulating human Th17 cells via differential expression of IL-1 receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Long-term augmentation therapy with alpha-1 antitrypsin in an MZ-AAT severe persistent asthma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Protease-activated receptors in cardiovascular health and diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Neutrophil elastase cleaves VEGF to generate a VEGF fragment with altered activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Detection of alpha-1 antitrypsin deficiency: a review.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Acute phase proteins in atherosclerosis (acute coronary syndrome).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

PI S and PI Z alpha-1 antitrypsin deficiency worldwide. A review of existing genetic epidemiological data

28 September 2017

1 reference

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Matrix metalloproteinase-9/gelatinase B is a putative therapeutic target of chronic obstructive pulmonary disease and multiple sclerosis

28 September 2017

1 reference

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Comparison of the effects of serpin A1, a recombinant serpin A1-IGF chimera and serpin A1 C-terminal peptide on wound healing

28 September 2017

1 reference

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Aralast: an alpha 1-protease inhibitor for the treatment of alpha-antitrypsin deficiency

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha1-antitrypsin protects beta-cells from apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

The pathogenesis of COPD: lessons learned from in vivo animal models.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Role of lung maintenance program in the heterogeneity of lung destruction in emphysema

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Recombinant human alpha-1 proteinase inhibitor: towards therapeutic use.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

28 September 2017

Trypsin and Antitrypsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

The C-terminal 26-residue peptide of serpin A1 is an inhibitor of HIV-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Saving islets from allograft rejection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Aggrecanase-1 (ADAMTS-4) interacts with alpha1-antitrypsin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha1-antitrypsin inhibits angiogenesis and tumor growth

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Application of transgenesis in livestock for agriculture and biomedicine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Protease-activated receptor-2 signaling triggers dendritic cell development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

The anti-inflammatory actions of antithrombin--a review

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Antimicrobial activity of antiproteinases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

In vivo complex formation of oxidized alpha(1)-antitrypsin and LDL.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Leukocyte elastase: physiological functions and role in acute lung injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Epstein-Barr virus/human vector provides high-level, long-term expression of alpha1-antitrypsin in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha-1-antitrypsin inhibits human immunodeficiency virus type 1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Augmentation therapy reduces frequency of lung infections in antitrypsin deficiency: a new hypothesis with supporting data

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha1-antitrypsin alleles and phenotypes in patients with inflammatory bowel disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha 1-antitrypsin blocks the release of transforming growth factor-alpha from MCF-7 human breast cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Cell-specific expression of alpha 1-antitrypsin in human intestinal epithelium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Clinical features and molecular characteristics of alpha 1-antitrypsin deficiency.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Hypoxia, a novel inducer of acute phase gene expression in a human hepatoma cell line

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Role of interleukin-1 in augmenting serum neutralization of bacterial lipopolysaccharide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

α1-Antitrypsin is an effector of immunological stasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

HIV infection is associated with reduced serum alpha-1-antitrypsin concentrations.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

α 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic β-cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Combination of alpha-1 antitrypsin and doxycycline suppresses collagen-induced arthritis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha 1-antitrypsin in cerebrospinal fluid of patients with neurologic diseases.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Serum alpha 1-protease inhibitor in diabetes mellitus: reduced concentration and impaired activity.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Endocytosis and degradation of alpha 1-antitrypsin-protease complexes is mediated by the serpin-enzyme complex (SEC) receptor

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

The SEC receptor recognizes a pentapeptide neodomain of alpha 1-antitrypsin-protease complexes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Enhancement of growth of virulent strains of Escherichia coli by interleukin-1.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Fibromyalgia, mood disorders, and intense creative energy: A1AT polymorphisms are not always silent.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Serum trypsin inhibitory capacity in normal pregnancy and gestational diabetes mellitus

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Control of inflammation with alpha1-antitrypsin: a potential treatment for islet transplantation and new-onset type 1 diabetes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha 1 antitrypsin activity is decreased in human amnion in premature rupture of the fetal membranes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

An association between Type 2 diabetes and alpha-antitrypsin deficiency

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Reference values for alpha1-acid glycoprotein, alpha1-antitrypsin, albumin, haptoglobin, C-reactive protein, IgA, IgG and IgM during pregnancy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha-1 antitrypsin treatment of spontaneously diabetic nonobese diabetic mice receiving islet allografts

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Trypsin, elastase, plasmin and MMP-9 activity in the serum during the human ageing process

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Art, alpha-1-antitrypsin polymorphisms and intense creative energy: blessing or curse?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Serum protease inhibitor concentrations and total antitrypsin activity in diabetic and non-diabetic children during adolescence.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Inhaled recombinant alpha 1-antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

A role for proteinase-activated receptor-1 in inflammatory bowel diseases.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha1-antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

C-36 peptide, a degradation product of alpha1-antitrypsin, modulates human monocyte activation through LPS signaling pathways

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Alpha1-antitrypsin inhibits Moraxella catarrhalis MID protein-induced tonsillar B cell proliferation and IL-6 release

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Expression and secretion of alpha1-proteinase inhibitor are regulated by proinflammatory cytokines in human pancreatic islet cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

A heat shock protein70 fusion protein with alpha1-antitrypsin in plasma of type 1 diabetic subjects

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Divergent effects of alpha1-antitrypsin on neutrophil activation, in vitro

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Protective effects of alpha 1-antitrypsin on acute lung injury in rabbits induced by endotoxin.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

α-1-Antitrypsin Ameliorates Cigarette Smoke–induced Emphysema in the Mouse

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Polyethylene glycol conjugation at Cys232 prolongs the half-life of alpha1 proteinase inhibitor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Cytokine regulatory effects on alpha-1 proteinase inhibitor expression in NOD mouse islet endothelial cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

The serpin alpha1-proteinase inhibitor is a critical substrate for gelatinase B/MMP-9 in vivo.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Novel functions of human alpha(1)-protease inhibitor after S-nitrosylation: inhibition of cysteine protease and antibacterial activity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Pulmonary epithelial expression of human alpha1-antitrypsin in transgenic mice results in delivery of alpha1-antitrypsin protein to the interstitium

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459478

Sustained expression of circulating human alpha-1 antitrypsin reduces inflammation, increases CD4+FoxP3+ Treg cell population and prevents signs of experimental autoimmune encephalomyelitis in mice

28 November 2018

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Deletion of Serpina1a, a murine α1-antitrypsin ortholog, results in embryonic lethality

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

C-terminal fragment of alpha1-antitrypsin activates human monocytes to a pro-inflammatory state through interactions with the CD36 scavenger receptor and LDL receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Atherogenic properties of human monocytes induced by the carboxyl terminal proteolytic fragment of alpha-1-antitrypsin

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

The carboxyl-terminal fragment of alpha1-antitrypsin is present in atherosclerotic plaques and regulates inflammatory transcription factors in primary human monocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Alpha(1)-proteinase inhibitor, alpha(1)-antichymotrypsin, or alpha(2)-macroglobulin is required for vascular smooth muscle cell spreading in three-dimensional fibrin gel

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Alpha1-antitrypsin deficiency: more than a protease imbalance?

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

The use of interleukin-1-receptor antagonists in the treatment of diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Preliminary studies related to anti-interleukin-1β therapy in children with newly diagnosed type 1 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Impaired activity of serum alpha-1-antitrypsin in diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Specific activity of alpha1proteinase inhibitor and alpha2macroglobulin in human serum: application to insulin-dependent diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Functional activities and nonenzymatic glycosylation of plasma proteinase inhibitors in diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Relationship between α1-antitrypsin inactivation and tumor necrosis factor α concentration in the synovial fluid of patients with rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Suppressive effect of a neutrophil elastase inhibitor on the development of collagen-induced arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Alpha-1-antitrypsin phenotypes and associated disease patterns in neurological patients

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Alpha-1 antitrypsin phenotypes in demyelinating disease: an association between demyelinating disease and the allele PiM3

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Population-based case-control study of alpha 1-antitrypsin and SLC11A1 in Crohn's disease and ulcerative colitis

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Functional protection by acute phase proteins alpha(1)-acid glycoprotein and alpha(1)-antitrypsin against ischemia/reperfusion injury by preventing apoptosis and inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

The relationship between trypsin activity in amniotic fluid and premature rupture of membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Longitudinal follow-up of patients with alpha(1)-protease inhibitor deficiency before and during therapy with IV alpha(1)-protease inhibitor

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

Alpha1-antitrypsin, old dog, new tricks. Alpha1-antitrypsin exerts in vitro anti-inflammatory activity in human monocytes by elevating cAMP

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

C1 inhibitor: just a serine protease inhibitor? New and old considerations on therapeutic applications of C1 inhibitor

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00196

High alpha-1 antitrypsin clearance predicts severity of gut graft-versus-host disease (GVHD) in children

31 March 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/22634722

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Interleukin-1 receptor antagonist-treatment of patients with type 2 diabetes]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22634722

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A role for proteinase-activated receptor-1 in inflammatory bowel diseases

1 reference

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI21689

Identifiers

DOI

10.2119/MOLMED.2011.00196

1 reference

Dimensions Publication ID

1695529

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.2119/molmed.2011.00196

1695529

1 reference

1 reference

1 reference