HIV therapeutic vaccines: moving towards a functional cure (Q27002180)

Crossref

language of work or name

1 reference

August 2015

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Current Opinion in Immunology

published in

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volume

35

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page(s)

1-8

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Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

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AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

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Diminished viral control during simian immunodeficiency virus infection is associated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa.

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Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

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Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

28 September 2017

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Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

28 September 2017

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Immune clearance of highly pathogenic SIV infection

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Therapeutic and prophylactic DNA vaccines for HIV-1.

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Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques

28 September 2017

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A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication

28 September 2017

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Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

28 September 2017

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28 September 2017

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Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

28 September 2017

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28 September 2017

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Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

28 September 2017

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Immune reconstitution under antiretroviral therapy: the new challenge in HIV-1 infection

28 September 2017

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28 September 2017

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CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

28 September 2017

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Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.

28 September 2017

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Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys

28 September 2017

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PD-1 and CTLA-4 inhibitory cosignaling pathways in HIV infection and the potential for therapeutic intervention

28 September 2017

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28 September 2017

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28 September 2017

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Immune activation driven by CTLA-4 blockade augments viral replication at mucosal sites in simian immunodeficiency virus infection.

28 September 2017

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Multiple-cytokine-producing antiviral CD4 T cells are functionally superior to single-cytokine-producing cells

28 September 2017

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SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

28 September 2017

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Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination

28 September 2017

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Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection

28 September 2017

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Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection

28 September 2017

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Structured treatment interruptions for the management of HIV infection

28 September 2017

1 reference

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Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects

28 September 2017

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Dendritic cell-based therapeutic vaccine elicits polyfunctional HIV-specific T-cell immunity associated with control of viral load

28 September 2017

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HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome

31 May 2018

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CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads

31 May 2018

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Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

28 November 2018

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Defective IL-2 production by HIV-1-specific CD4 and CD8 T cells in an adolescent/young adult cohort.

28 November 2018

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Therapeutic dendritic-cell vaccine for chronic HIV-1 infection

28 November 2018

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28 November 2018

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Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses

28 November 2018

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Loss of blood CD11c(+) myeloid and CD11c(-) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load

28 November 2018

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Control of SIV rebound through structured treatment interruptions during early infection

28 November 2018

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Immune control of HIV-1 after early treatment of acute infection

28 November 2018

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Viremia control following antiretroviral treatment and therapeutic immunizationduring primary SIV251 infection of macaques

28 November 2018

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Human immunodeficiency virus type 1-specific cytotoxic T lymphocyte activity is inversely correlated with HIV type 1 viral load in HIV type 1-infected long-term survivors

28 November 2018

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Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection

28 November 2018

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12 December 2020

DNA immunization in combination with effective antiretroviral drug therapy controls viral rebound and prevents simian AIDS after treatment is discontinued

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12 December 2020

Depletion in blood CD11c-positive dendritic cells from HIV-infected patients

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12 December 2020

Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals

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12 December 2020

Antiretroviral therapy in early HIV infection

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12 December 2020

Immune reconstitution in the sigmoid colon after long-term HIV therapy

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12 December 2020

Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients

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12 December 2020

Immune reconstitution and control of HIV

1 reference

12 December 2020

Emergence of Cytotoxic T Lymphocyte Escape Mutants following Antiretroviral Treatment Suspension in Rhesus Macaques Infected with SIVmac251

1 reference

12 December 2020