DRiPs solidify: progress in understanding endogenous MHC class I antigen processing (Q27006750)

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November 2011

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32

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issue

11

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page(s)

548-58

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A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation

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Alternative pathways for MHC class I presentation: a new function for autophagy

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28 September 2017

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The central repeat domain 1 of Kaposi's sarcoma-associated herpesvirus (KSHV) latency associated-nuclear antigen 1 (LANA1) prevents cis MHC class I peptide presentation

28 September 2017

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Cutting Edge: Selective role of ubiquitin in MHC class I antigen presentation

28 September 2017

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28 September 2017

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28 September 2017

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Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast

28 September 2017

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The transporter associated with antigen processing (TAP) is active in a post-ER compartment

28 September 2017

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RNA polymerase II inhibitors dissociate antigenic peptide generation from normal viral protein synthesis: a role for nuclear translation in defective ribosomal product synthesis?

28 September 2017

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Epstein Barr virus-encoded EBNA1 interference with MHC class I antigen presentation reveals a close correlation between mRNA translation initiation and antigen presentation

28 September 2017

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Soluble plasma HLA peptidome as a potential source for cancer biomarkers

28 September 2017

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28 September 2017

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CD8+ T cell recognition of cryptic epitopes is a ubiquitous feature of AIDS virus infection

28 September 2017

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Folding of matrix metalloproteinase-2 prevents endogenous generation of MHC class-I restricted epitope

28 September 2017

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mTORC1 links protein quality and quantity control by sensing chaperone availability

28 September 2017

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Visualizing high error levels during gene expression in living bacterial cells.

28 September 2017

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Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules.

28 September 2017

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Making sense of antisense: seemingly noncoding RNAs antisense to the master regulator of Kaposi's sarcoma-associated herpesvirus lytic replication do not regulate that transcript but serve as mRNAs encoding small peptides

28 September 2017

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Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action.

28 September 2017

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The synthesis of truncated polypeptides for immune surveillance and viral evasion

28 September 2017

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Defective ribosomal products are the major source of antigenic peptides endogenously generated from influenza A virus neuraminidase

28 September 2017

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T cell detection of a B-cell tropic virus infection: newly-synthesised versus mature viral proteins as antigen sources for CD4 and CD8 epitope display

28 September 2017

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Innate immune and chemically triggered oxidative stress modifies translational fidelity.

28 September 2017

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Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responses

28 September 2017

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Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

28 September 2017

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28 September 2017

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A distinct translation initiation mechanism generates cryptic peptides for immune surveillance

28 September 2017

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Gly-Ala repeats induce position- and substrate-specific regulation of 26 S proteasome-dependent partial processing

28 September 2017

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Relevance of viral context and diversity of antigen-processing routes for respiratory syncytial virus cytotoxic T-lymphocyte epitopes

28 September 2017

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Regulation of protein translation through mRNA structure influences MHC class I loading and T cell recognition.

28 September 2017

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The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation

28 September 2017

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Cutting edge: MHC class I-Ly49 interaction regulates neuronal function.

28 September 2017

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28 September 2017

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28 September 2017

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Regulation of translation is required for dendritic cell function and survival during activation

28 September 2017

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Targeting HIV-1 Gag into the defective ribosomal product pathway enhances MHC class I antigen presentation and CD8+ T cell activation

28 September 2017

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AIDS virus specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escape

28 September 2017

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A novel cytosolic class I antigen-processing pathway for endoplasmic-reticulum-targeted proteins

28 September 2017

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Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function

28 September 2017

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Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation.

28 September 2017

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Viral alteration of cellular translational machinery increases defective ribosomal products

28 September 2017

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Rethinking peptide supply to MHC class I molecules

28 September 2017

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Proteasome-independent HLA-B27 ligands arise mainly from small basic proteins

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Cross-priming utilizes antigen not available to the direct presentation pathway.

28 September 2017

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Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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The seven dirty little secrets of major histocompatibility complex class I antigen processing

28 September 2017

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Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation.

28 September 2017

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Does protein synthesis occur in the nucleus?

28 September 2017

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Identification of cryptic MHC I-restricted epitopes encoded by HIV-1 alternative reading frames

28 September 2017

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28 September 2017

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Making sense of mass destruction: quantitating MHC class I antigen presentation

28 September 2017

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28 September 2017

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28 September 2017

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Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

28 September 2017

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To DRiP or not to DRiP: generating peptide ligands for MHC class I molecules from biosynthesized proteins

28 September 2017

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Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing

28 September 2017

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28 September 2017

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Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

28 September 2017

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A single naturally processed measles virus peptide fully dominates the HLA-A*0201-associated peptide display and is mutated at its anchor position in persistent viral strains

28 September 2017

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Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses.

28 September 2017

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Generating MHC class I ligands from viral gene products

28 September 2017

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Intracellular localization of proteasomal degradation of a viral antigen

28 September 2017

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The making of the dominant MHC class I ligand SYFPEITHI.

28 September 2017

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The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol

28 September 2017

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Introduction of a glycosylation site into a secreted protein provides evidence for an alternative antigen processing pathway: transport of precursors of major histocompatibility complex class I-restricted peptides from the endoplasmic reticulum to t

28 September 2017

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MHC class I-associated peptides produced from endogenous gene products with vastly different efficiencies.

28 September 2017

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Interphase nuclei of many mammalian cell types contain deep, dynamic, tubular membrane-bound invaginations of the nuclear envelope

28 September 2017

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Ribosomal scanning past the primary initiation codon as a mechanism for expression of CTL epitopes encoded in alternative reading frames

28 September 2017

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28 September 2017

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Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen

28 September 2017

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Genes coding for T-cell-defined tum transplantation antigens: point mutations, antigenic peptides, and subgenic expression

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RMA/S cells present endogenously synthesized cytosolic proteins to class I-restricted cytotoxic T lymphocytes

28 September 2017

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MHC class I: an unexpected role in neuronal plasticity

28 September 2017

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Fluorescent proteins: a cell biologist's user guide

31 May 2018

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Major histocompatibility class I molecules can present cryptic translation products to T-cells

31 May 2018

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Protein degradation in cultured cells. The effect of fresh medium, fluoride, and iodoacetate on the digestion of cellular protein of rat fibroblasts.

31 May 2018

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A frameshift mutation at the NH2 terminus of the nucleoprotein gene does not affect generation of cytotoxic T lymphocyte epitopes

31 May 2018

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Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Viral and bacterial minigene products are presented by MHC class I molecules with similar efficiencies

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Expression hierarchy of T cell epitopes from melanoma differentiation antigens: unexpected high level presentation of tyrosinase-HLA-A2 Complexes revealed by peptide-specific, MHC-restricted, TCR-like antibodies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Distorted relation between mRNA copy number and corresponding major histocompatibility complex ligand density on the cell surface.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Understanding GFP posttranslational chemistry: structures of designed variants that achieve backbone fragmentation, hydrolysis, and decarboxylation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

The turnover kinetics of major histocompatibility complex peptides of human cancer cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Characterization of rapidly degraded polypeptides in mammalian cells reveals a novel layer of nascent protein quality control.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Self-inhibition of synthesis and antigen presentation by Epstein-Barr virus-encoded EBNA1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Constitutive display of cryptic translation products by MHC class I molecules

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Systematic search fails to detect immunogenic MHC class-I-restricted determinants encoded by influenza A virus noncoding sequences

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Kinetics of degradation of "short-" and "long-lived" proteins in cultured mammalian cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Biology of simian virus 40 (SV40) transplantation antigen (TrAg). IX. Analysis of TrAg in mouse cells synthesizing truncated SV40 large T antigen

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200450

Cytotoxic T cells recognize fragments of the influenza nucleoprotein

28 November 2018

1 reference

12 December 2020

Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence

1 reference

12 December 2020

Cells process exogenous proteins for recognition by cytotoxic T lymphocytes

1 reference

12 December 2020

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody

1 reference

12 December 2020

Dissociation of proteasomal degradation of biosynthesized viral proteins from generation of MHC class I-associated antigenic peptides

1 reference

12 December 2020

Protein turnover in mammaliar cell cultures

1 reference

12 December 2020

Allele-selective effect of PA28 in MHC class I antigen processing

1 reference

12 December 2020

Direct visualization of the dynamics of antigen presentation in human cells infected with cytomegalovirus revealed by antibodies mimicking TCR specificity

1 reference

12 December 2020

Head-head/tail-tail relative orientation of the pore-forming domains of the heterodimeric ABC transporter TAP

1 reference

12 December 2020

The case for nuclear translation

1 reference

12 December 2020

The structure and location of SIMP/STT3B account for its prominent imprint on the MHC I immunopeptidome

1 reference

12 December 2020

The DRiP hypothesis decennial: support, controversy, refinement and extension

1 reference

12 December 2020

The major substrates for TAP in vivo are derived from newly synthesized proteins

1 reference

12 December 2020

Cutting edge: neosynthesis is required for the presentation of a T cell epitope from a long-lived viral protein

1 reference

12 December 2020

Identifiers

DOI

10.1016/J.IT.2011.08.001

1 reference

2561889

2561889

1 reference

1 reference

1 reference