Hepatitis B: future curative strategies (Q27011623)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25304392%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Laura Rivino

series ordinal

2

1 reference

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5 June 2020

language of work or name

1 reference

December 2014

1 reference

Current Opinion in Infectious Diseases

1 December 2014

9 references

23 March 2019

21 March 2019

22 June 2019

7 October 2019

3 November 2019

27 October 2020

28 January 2021

25 October 2022

26 October 2022

11 references

23 March 2019

21 March 2019

22 June 2019

7 October 2019

3 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25304392%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

27 October 2020

28 January 2021

25 October 2022

26 October 2022

27

2 references

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5 June 2020

issue

6

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5 June 2020

page(s)

528-534

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

5 June 2020

copyright license

9 references

23 March 2019

21 March 2019

22 June 2019

7 October 2019

3 November 2019

27 October 2020

28 January 2021

25 October 2022

on focus list of Wikimedia project

26 October 2022

ScienceSource

0 references

cites work

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Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver

28 September 2017

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28 September 2017

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Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

28 September 2017

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Immunological and antiviral responses after therapeutic DNA immunization in chronic hepatitis B patients efficiently treated by analogues.

28 September 2017

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Immune therapeutic strategies in chronic hepatitis B virus infection: virus or inflammation control?

28 September 2017

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Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes.

28 September 2017

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An efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases

28 September 2017

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Interleukin-1 and tumor necrosis factor-α trigger restriction of hepatitis B virus infection via a cytidine deaminase activation-induced cytidine deaminase (AID)

28 September 2017

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A practical approach to immunotherapy of hepatocellular carcinoma using T cells redirected against hepatitis B virus

28 September 2017

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Mobilizing monocytes to cross-present circulating viral antigen in chronic infection.

28 September 2017

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CD40 activation rescues antiviral CD8⁺ T cells from PD-1-mediated exhaustion.

28 September 2017

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Combination of DNA prime--adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model

28 September 2017

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The third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cells

28 September 2017

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Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection

28 September 2017

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GS-9620, an oral agonist of Toll-like receptor-7, induces prolonged suppression of hepatitis B virus in chronically infected chimpanzees

28 September 2017

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Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.

28 September 2017

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DNA prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model

28 September 2017

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Preserved T-cell function in children and young adults with immune-tolerant chronic hepatitis B.

28 September 2017

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Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection

28 September 2017

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28 September 2017

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Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines

28 September 2017

1 reference

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The molecular basis of the failed immune response in chronic HBV: therapeutic implications

28 September 2017

1 reference

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Therapeutic vaccination and novel strategies to treat chronic HBV infection

28 September 2017

1 reference

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A lymphotoxin-driven pathway to hepatocellular carcinoma

28 September 2017

1 reference

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Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

28 September 2017

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Rational design of a multiepitope vaccine encoding T-lymphocyte epitopes for treatment of chronic hepatitis B virus infections

28 September 2017

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Tumor necrosis factor activates a conserved innate antiviral response to hepatitis B virus that destabilizes nucleocapsids and reduces nuclear viral DNA.

28 September 2017

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Longitudinal analysis of CD8+ T cells specific for structural and nonstructural hepatitis B virus proteins in patients with chronic hepatitis B: implications for immunotherapy

28 September 2017

1 reference

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MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

28 September 2017

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CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection

28 September 2017

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Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice.

28 September 2017

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Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections

28 September 2017

1 reference

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Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Immunotherapy of chronic hepatitis B by anti HBV vaccine: from present to future

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Is a function of the secreted hepatitis B e antigen to induce immunologic tolerance in utero?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Anti-HBV DNA vaccination does not prevent relapse after discontinuation of analogues in the treatment of chronic hepatitis B: a randomised trial--ANRS HB02 VAC-ADN.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Nanoparticles encapsulating hepatitis B virus cytosine-phosphate-guanosine induce therapeutic immunity against HBV infection

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Targeted delivery of interferon-α to hepatitis B virus-infected cells using T-cell receptor-like antibodies

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Targeting innate immunity: a new step in the development of combination therapy for chronic hepatitis B.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Results of a phase III clinical trial with an HBsAg-HBIG immunogenic complex therapeutic vaccine for chronic hepatitis B patients: experiences and findings.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

IL-7 Licenses Activation of Human Liver Intrasinusoidal Mucosal-Associated Invariant T Cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Therapeutic recovery of hepatitis B virus (HBV)-induced hepatocyte-intrinsic immune defect reverses systemic adaptive immune tolerance

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Early kinetics of innate and adaptive immune responses during hepatitis B virus infection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Anti-HBs re-seroconversion after liver transplantation in a patient with past HBV infection receiving a HBsAg positive graft

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Therapeutic vaccination of chronic hepatitis B patients with virus suppression by antiviral therapy: a randomized, controlled study of co-administration of HBsAg/AS02 candidate vaccine and lamivudine

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

A pilot study of the CY-1899 T-cell vaccine in subjects chronically infected with hepatitis B virus. The CY1899 T Cell Vaccine Study Group

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Clearance of hepatitis B surface antigen after bone marrow transplantation: Role of adoptive immunity transfer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232294

Induction or expansion of T-cell responses by a hepatitis B DNA vaccine administered to chronic HBV carriers

28 November 2018

1 reference

12 December 2020

Hepatitis B virus persistence after recovery from acute viral hepatitis

1 reference

12 December 2020

Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues

1 reference

12 December 2020

Efficacy and limitations of a specific immunotherapy in chronic hepatitis B

1 reference

12 December 2020

10.1097/QCO.0000000000000110

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25304392%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25304392%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25304392%20AND%20SRC:MED&resulttype=core&format=json