Structures of usher syndrome 1 proteins and their complexes (Q27023615)

language of work or name

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February 2012

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27

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PubMed

issue

1

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PubMed

page(s)

25-42

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Interactions in the network of Usher syndrome type 1 proteins

PubMed

cites work

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The molecular genetics of Usher syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Nonsyndromic recessive deafness DFNB18 and Usher syndrome type IC are allelic mutations of USHIC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Connecting the ear to the brain: Molecular mechanisms of auditory circuit assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Three-dimensional architecture of hair-bundle linkages revealed by electron-microscopic tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Models for the Specific Adhesion of Cells to Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

C-cadherin ectodomain structure and implications for cell adhesion mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Usher syndrome: definition and estimate of prevalence from two high-risk populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

PDZ proteins organize synaptic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Usher I syndrome: unravelling the mechanisms that underlie the cohesion of the growing hair bundle in inner ear sensory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutation of a gene encoding a protein with extracellular matrix motifs in Usher syndrome type IIa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The sensory and motor roles of auditory hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Human Nonsyndromic Sensorineural Deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Molecular evolution of the vertebrate mechanosensory cell and ear

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Genetic insights into the morphogenesis of inner ear hair cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cross-links between stereocilia in the guinea pig cochlea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The dimensions and composition of stereociliary rootlets in mammalian cochlear hair cells: comparison between high- and low-frequency cells and evidence for a connection to the lateral membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Developmental acquisition of sensory transduction in hair cells of the mouse inner ear

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mechanotransduction by hair cells: models, molecules, and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Molecular basis of mechanosensory transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Asymmetric distribution of cadherin 23 and protocadherin 15 in the kinocilial links of avian sensory hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Development and properties of stereociliary link types in hair cells of the mouse cochlea

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Harmonin inhibits presynaptic Cav1.3 Ca²⁺ channels in mouse inner hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Harmonin mutations cause mechanotransduction defects in cochlear hair cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The kinetic mechanism of mouse myosin VIIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

A new spontaneous mutation in the mouse Ames waltzer gene, Pcdh15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Unconventional myosins in inner-ear sensory epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Function and expression pattern of nonsyndromic deafness genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

21 January 2018

How the ear's works work

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Making an effort to listen: mechanical amplification in the ear

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Characterization of the motor activity of mammalian myosin VIIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mouse models of USH1C and DFNB18: phenotypic and molecular analyses of two new spontaneous mutations of the Ush1c gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Shaping the mammalian auditory sensory organ by the planar cell polarity pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Forces between clustered stereocilia minimize friction in the ear on a subnanometre scale.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Coherent motion of stereocilia assures the concerted gating of hair-cell transduction channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Usher syndrome: molecular links of pathogenesis, proteins and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Functional analysis of Slac2-c/MyRIP as a linker protein between melanosomes and myosin VIIa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Ankyrin repeat: a unique motif mediating protein-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutations in the myosin VIIA gene cause non-syndromic recessive deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cell adhesion: ushering in a new understanding of myosin VII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cadherin 23 is a component of the transient lateral links in the developing hair bundles of cochlear sensory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

An update on the genetics of usher syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Characterization of a myosin VII MyTH/FERM domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cadherins and mechanotransduction by hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Development of the hair bundle and mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutations in the alternatively spliced exons of USH1C cause non-syndromic recessive deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Type II cadherin ectodomain structures: implications for classical cadherin specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Usher syndrome: from genetics to pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Linking genes underlying deafness to hair-bundle development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cross-links between stereocilia in the guinea pig organ of Corti, and their possible relation to sensory transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Structure and mechanism of cadherins and catenins in cell-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Differential distribution of harmonin isoforms and their possible role in Usher-1 protein complexes in mammalian photoreceptor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Molecular analysis of the supramolecular usher protein complex in the retina. Harmonin as the key protein of the Usher syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

How the genetics of deafness illuminates auditory physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cargo binding activates myosin VIIA motor function in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Structure and biochemistry of cadherins and catenins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cadherin 23 is a component of the tip link in hair-cell stereocilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Structural determinants of cadherin-23 function in hearing and deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Unconventional myosin VIIa and vezatin, two proteins crucial for Listeria entry into epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cadherins and their connections: adhesion junctions have broader functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Identification of a novel frameshift mutation in the DFNB31/WHRN gene in a Tunisian consanguineous family with hereditary non-syndromic recessive hearing loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The tail binds to the head-neck domain, inhibiting ATPase activity of myosin VIIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Identification of 51 novel exons of the Usher syndrome type 2A (USH2A) gene that encode multiple conserved functional domains and that are mutated in patients with Usher syndrome type II

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The micromachinery of mechanotransduction in hair cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Human hereditary hearing impairment: mouse models can help to solve the puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Defective myosin VIIA gene responsible for Usher syndrome type 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Human myosin VIIA responsible for the Usher 1B syndrome: a predicted membrane-associated motor protein expressed in developing sensory epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Genomic structure and identification of novel mutations in usherin, the gene responsible for Usher syndrome type IIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type II

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Cadherins as Modulators of Cellular Phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Usher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The cellular function of the usher gene product myosin VIIa is specified by its ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Analysis of subcellular localization of Myo7a, Pcdh15 and Sans in Ush1c knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Genetics and pathological mechanisms of Usher syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

A FERM domain autoregulates Drosophila myosin 7a activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Dimerized Drosophila myosin VIIa: a processive motor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Myosin VI undergoes cargo-mediated dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Organization of signaling complexes by PDZ-domain scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

Targeting of the hair cell proteins cadherin 23, harmonin, myosin XVa, espin, and prestin in an epithelial cell model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00037.2011

10.1152/PHYSIOL.00037.2011

21 January 2018

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

22311968

1 reference

Consolidated OpenCitations Corpus – April 2017