Insulitis in human type 1 diabetes: a comparison between patients and animal models (Q27023712)

language of work or name

1 reference

September 2014

1 reference

Seminars in Immunopathology

1 September 2014

6 references

14 March 2019

24 March 2019

30 June 2019

5 August 2019

7 October 2019

10 October 2019

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14 March 2019

24 March 2019

30 June 2019

5 August 2019

7 October 2019

10 October 2019

36

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issue

5

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page(s)

569-79

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Creative Commons Attribution 4.0 International

copyright license

start time

9 July 2014

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April 2022 Public Data File from Crossref

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes

21 March 2017

1 reference

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Type 1 diabetes: translating mechanistic observations into effective clinical outcomes

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Opinion: Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Predictors of progression to Type 1 diabetes: preparing for immune interventions in the preclinical disease phase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Soluble factors secreted by T cells promote β-cell proliferation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

On the etiology of type 1 diabetes: a new animal model signifying a decisive role for bacteria eliciting an adverse innate immunity response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Fall in C-peptide during first 2 years from diagnosis: evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Insulitis in human type 1 diabetes: The quest for an elusive lesion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Type 1 diabetes: etiology, immunology, and therapeutic strategies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Beta-cell replication is increased in donor organs from young patients after prolonged life support

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Quantification and three-dimensional imaging of the insulitis-induced destruction of beta-cells in murine type 1 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Prevention of diabetes by FTY720-mediated stabilization of peri-islet tertiary lymphoid organs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Microscopic anatomy of the human islet of Langerhans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

The Pathology of Diabetes, with Special Reference to Pancreatic Regeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Analysis of islet inflammation in human type 1 diabetes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Screening for insulitis in adult autoantibody-positive organ donors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Lymphoid neogenesis in chronic inflammatory diseases.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

The NOD mouse: a model of immune dysregulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Animal models have little to teach us about type 1 diabetes: 2. In opposition to this proposal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Animal models have little to teach us about type 1 diabetes: 1. In support of this proposal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

The discovery of type 1 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Lymphoid tissue homing chemokines are expressed in chronic inflammation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Heterogeneity of islet pathology in two infants with recent onset diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

The pancreas in recent-onset type 1 (insulin-dependent) diabetes mellitus: insulin content of islets, insulitis and associated changes in the exocrine acinar tissue

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Fulminating diabetes with lymphocytic thyroiditis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Type I diabetes mellitus. A chronic autoimmune disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Pancreatic beta cells in insulin-dependent diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

An autopsy study of the islets of Langerhans in acute-onset juvenile diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Isolation of a virus from the pancreas of a child with diabetic ketoacidosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Insulitis and peracute diabetes mellitus (author's transl)

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Islet cell survival determined by morphology. An immunocytochemical study of the islets of Langerhans in juvenile diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Gene expression profiles for the human pancreas and purified islets in type 1 diabetes: new findings at clinical onset and in long-standing diabetes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

A STUDY OF THE PATHOLOGICAL ANATOMY OF THE PANCREAS IN NINETY CASES OF DIABETES MELLITUS.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Fatal cerebral oedema with insulitis in diabetic ketoacidosis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Large human islets secrete less insulin per islet equivalent than smaller islets in vitro

31 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

Pancreatic isleitis with coxsackie virus B5 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

Analysis of pancreas tissue in a child positive for islet cell antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

The diagnosis of insulitis in human type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

Evidence of increased islet cell proliferation in patients with recent-onset type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

Deficiency in type I interferon signaling prevents the early interferon-induced gene signature in pancreatic islets but not type 1 diabetes in NOD mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186970

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

28 November 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-014-0438-4

Pathologic anatomy of the pancreas in juvenile diabetes mellitus

21 January 2018

1 reference

12 December 2020

Morphometric evidence for a striking B-cell reduction at the clinical onset of type 1 diabetes

1 reference

12 December 2020

Cellular composition of the human diabetic pancreas

1 reference

12 December 2020

Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies

1 reference

12 December 2020

Initial results of screening of nondiabetic organ donors for expression of islet autoantibodies

1 reference

12 December 2020

Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile

1 reference

12 December 2020

Islets of Langerhans in juvenile diabetes mellitus

1 reference

12 December 2020

The NOD mouse: a model for insulin-dependent diabetes mellitus

1 reference

12 December 2020

Residual insulin positivity and pancreatic atrophy in relation to duration of chronic Type 1 (insulin-dependent) diabetes mellitus and microangiopathy

1 reference

12 December 2020

Lack of immunohistological changes in the islets of nondiabetic, autoimmune, polyendocrine patients with beta-selective GAD-specific islet cell antibodies

1 reference

12 December 2020

Aberrant expression of class II major histocompatibility complex molecules by B cells and hyperexpression of class I major histocompatibility complex molecules by insulin containing islets in type 1 (insulin-dependent) diabetes mellitus

1 reference

12 December 2020

Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans

1 reference

12 December 2020

Insulitis in early juvenile diabetes

1 reference

12 December 2020

Pancreatic biopsy as a procedure for detecting in situ autoimmune phenomena in type 1 diabetes: close correlation between serological markers and histological evidence of cellular autoimmunity

1 reference

12 December 2020

Macrophages and dendritic cells infiltrating islets with or without beta cells produce tumour necrosis factor-alpha in patients with recent-onset type 1 diabetes

1 reference

12 December 2020

T-cell insulitis found in anti-GAD65+ diabetes with residual beta-cell function. A case report

1 reference

12 December 2020

Relationships among residual β cells, exocrine pancreas, and islet cell antibodies in insulin-dependent diabetes mellitus

1 reference

12 December 2020

Insulitis in the human endocrine pancreas: does a viral infection lead to inflammation and beta cell replication?

1 reference

12 December 2020

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis

1 reference

12 December 2020

Effects of autoimmunity and immune therapy on beta-cell turnover in type 1 diabetes

1 reference

12 December 2020

Insulitis (Lymphocytic Infiltration of Pancreatic Islets) in Late-onset Diabetes

1 reference

12 December 2020

Dimorphic histopathology of long-standing childhood-onset diabetes

1 reference

12 December 2020

Immunohistochemical characterization of monocytes-macrophages and dendritic cells involved in the initiation of the insulitis and beta-cell destruction in NOD mice

1 reference

12 December 2020

Diabetic coma with acute inflammation of Islets of Langerhans

1 reference

12 December 2020

10.1007/S00281-014-0438-4

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DOI

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Dimensions Publication ID

1011951563

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Fatcat ID

release_z5ffz6wexvdvvclxwvhe3o4lxy

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Fatcat

https://api.fatcat.wiki/v0/release/z5ffz6wexvdvvclxwvhe3o4lxy

24 November 2022

mapped directly with Wikidata item

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PubMed publication ID

25005747

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