Bevacizumab treatment for advanced breast cancer (Q27027498)

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V. Guarneri

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F. Icli

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S. Johnston

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D. Khayat

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S. Loibl

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M. Martin

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C. Zielinski

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P. Conte

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G. N. Hortobagyi

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language of work or name

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2011

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16

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issue

12

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page(s)

1684-97

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Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

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21 March 2017

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

21 March 2017

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Angiogenesis in cancer and other diseases

21 March 2017

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A phase I/II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer

21 March 2017

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Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study

21 March 2017

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Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer

21 March 2017

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21 March 2017

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

7 April 2017

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Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma

7 April 2017

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Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

7 April 2017

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Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer

7 April 2017

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VEGF receptor signalling - in control of vascular function

7 April 2017

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Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

7 April 2017

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Regulation of angiogenesis by hypoxia: role of the HIF system

7 April 2017

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

7 April 2017

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7 April 2017

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What Is the Evidence That Tumors Are Angiogenesis Dependent?

7 April 2017

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7 April 2017

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In the end what matters most? A review of clinical endpoints in advanced breast cancer.

28 September 2017

1 reference

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Disease course patterns after discontinuation of bevacizumab: pooled analysis of randomized phase III trials

28 September 2017

1 reference

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Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer

28 September 2017

1 reference

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Overall survival and post-progression survival in advanced breast cancer: a review of recent randomized clinical trials

28 September 2017

1 reference

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Detecting an overall survival benefit that is derived from progression-free survival

28 September 2017

1 reference

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Independent review of E2100: a phase III trial of bevacizumab plus paclitaxel versus paclitaxel in women with metastatic breast cancer

28 September 2017

1 reference

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Anticancer strategies involving the vasculature

28 September 2017

1 reference

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Positive and negative modulation of angiogenesis by VEGFR1 ligands

28 September 2017

1 reference

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Relationship between effects on time-to-disease progression and overall survival in studies of metastatic breast cancer

28 September 2017

1 reference

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The role of neuropilins in cancer

28 September 2017

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Goals of treatment for patients with metastatic breast cancer

28 September 2017

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Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies.

28 September 2017

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Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer

28 September 2017

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Epidermal growth factor receptor in tumor angiogenesis

28 September 2017

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Vascular endothelial growth factor as a target for anticancer therapy

28 September 2017

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A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

28 September 2017

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Molecular mechanisms of lymphangiogenesis in health and disease

28 September 2017

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Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor

28 September 2017

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Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: pharmacologic and long-term safety data

28 September 2017

1 reference

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Prognostic value of vascular endothelial growth factor in breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248767

Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248767

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

28 September 2017

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VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

28 September 2017

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Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human p

31 May 2018

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The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies.

31 May 2018

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RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer

31 May 2018

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Significantly higher levels of vascular endothelial growth factor (VEGF) and shorter survival times for patients with primary operable triple-negative breast cancer.

28 November 2018

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VEGF as a marker for outcome among advanced breast cancer patients receiving anti-VEGF therapy with bevacizumab and vinorelbine chemotherapy

28 November 2018

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Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200

28 November 2018

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Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients

28 November 2018

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Correlation between progression free survival and response rate in patients with metastatic colorectal carcinoma.

28 November 2018

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Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

28 November 2018

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Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

28 November 2018

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12 December 2020

Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer

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12 December 2020

A monoclonal antibody that blocks VEGF binding to VEGFR2 (KDR/Flk-1) inhibits vascular expression of Flk-1 and tumor growth in an orthotopic human breast cancer model

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12 December 2020

Response rate or time to progression as predictors of survival in trials of metastatic colorectal cancer or non-small-cell lung cancer: a meta-analysis

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Identifiers

DOI

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Fatcat ID

release_so6ws6e4tbbqbjasy7si436nhy

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1 reference

PubMed publication ID

21976315

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