Indirect effects of glucagon-like peptide-1 receptor agonist exendin-4 on the peripheral circadian clocks in mice (Q27301386)

April 2022 Public Data File from Crossref

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Entrainment of the circadian clock in the liver by feeding

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Leptin activates hepatic 5'-AMP-activated protein kinase through sympathetic nervous system and α1-adrenergic receptor: a potential mechanism for improvement of fatty liver in lipodystrophy by leptin

28 September 2017

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Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice

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Exendin-4 improves blood glucose control in both young and aging normal non-diabetic mice, possible contribution of beta cell independent effects

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Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

28 September 2017

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A balanced diet is necessary for proper entrainment signals of the mouse liver clock

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Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humans

28 September 2017

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Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.

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Clock gene expression in peripheral leucocytes of patients with type 2 diabetes

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Rhythmic messenger ribonucleic acid expression of clock genes and adipocytokines in mouse visceral adipose tissue

21 January 2018

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Metabolic homeostasis in mice with disrupted Clock gene expression in peripheral tissues.

21 January 2018

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Improvement of glucose tolerance and hepatic insulin sensitivity by oligofructose requires a functional glucagon-like peptide 1 receptor.

21 January 2018

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Refeeding after fasting elicits insulin-dependent regulation of Per2 and Rev-erbα with shifts in the liver clock.

21 January 2018

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Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice

21 January 2018

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Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iepsilon (CKIepsilon)-dependent degradation of clock protein mPer2.

21 January 2018

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Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase.

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Physiological and Pharmacological Mechanisms through which the DPP-4 Inhibitor Sitagliptin Regulates Glycemia in Mice

21 January 2018

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Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24260546

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24260546