A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling (Q27301472)

1

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Elise Lavergne

2

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Ismaïl Hendaoui

3

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Harri Elamaa

4

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Ulla Tiirola

5

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Taina Pihlajaniemi

7

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Bruno Clément

8

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Orlando Musso

Creative Commons Attribution 4.0 International

9

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language of work or name

English

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publication date

2008

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published in

PLOS One

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volume

3

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issue

4

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page(s)

e1878

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copyright license

start time

2 April 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

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Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

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The Wnt antagonist sFRP1 in colorectal tumorigenesis

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The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases

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Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas

21 March 2017

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Mouse Col18a1 is expressed in a tissue-specific manner as three alternative variants and is localized in basement membrane zones

21 March 2017

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The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo

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Helping Wingless take flight: how WNT proteins are secreted

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WNTS and WNT receptors as therapeutic tools and targets in human disease processes.

28 September 2017

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Genetics of hepatocellular tumors.

28 September 2017

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Promoter methylation of the secreted frizzled-related protein 1 gene SFRP1 is frequent in hepatocellular carcinoma

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Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness

28 September 2017

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An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells

28 September 2017

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Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells.

28 September 2017

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Characterization of the human type XVIII collagen gene and proteolytic processing and tissue location of the variant containing a frizzled motif

28 September 2017

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Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

28 September 2017

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Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.

28 September 2017

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Infection of a human hepatoma cell line by hepatitis B virus

28 September 2017

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Matricellular proteins: extracellular modulators of cell function

28 September 2017

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Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis

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Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription

28 September 2017

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The promoter of the long variant of collagen XVIII, the precursor of endostatin, contains liver-specific regulatory elements.

28 September 2017

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Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

28 September 2017

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Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin

28 September 2017

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Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

28 September 2017

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Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

28 September 2017

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

28 September 2017

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trans-Acting factors, detoxication enzymes and hepatitis B virus replication in a novel set of human hepatoma cell lines

28 September 2017

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Alpha 1(XVIII), a collagen chain with frequent interruptions in the collagenous sequence, a distinct tissue distribution, and homology with type XV collagen

28 September 2017

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Overproduction of a truncated hepatocyte nuclear factor 3 protein inhibits expression of liver-specific genes in hepatoma cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270346

Mitochondrial metabolism of glutamine and glutamate and its physiological significance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270346

The short and long forms of type XVIII collagen show clear tissue specificities in their expression and location in basement membrane zones in humans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270346

Collagen XVIII is localized in sinusoids and basement membrane zones and expressed by hepatocytes and activated stellate cells in fibrotic human liver

31 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270346

Cell cycle regulation and apoptosis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270346

Characterization of the mouse gene for the alpha 1 chain of type XVIII collagen (Col18a1) reveals that the three variant N-terminal polypeptide forms are transcribed from two widely separated promoters

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270346

Identification of three N-terminal ends of type XVIII collagen chains and tissue-specific differences in the expression of the corresponding transcripts. The longest form contains a novel motif homologous to rat and Drosophila frizzled proteins.

31 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001878

Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001878

Beta-catenin accumulation in the progression of human hepatocarcinogenesis correlates with loss of E-cadherin and accumulation of p53, but not with expression of conventional WNT-1 target genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001878

Human bradykinin B2 receptor sialylation and N-glycosylation participate with disulfide bonding in surface receptor dimerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001878

Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270346

Interaction of endostatin with integrins implicated in angiogenesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270346

Tumor hepatocytes and basement membrane-Producing cells specifically express two different forms of the endostatin precursor, collagen XVIII, in human liver cancers

28 November 2018

1 reference

12 December 2020

Studies on plasma membranes. IV. The ultrastructural localization and content of sialic acid in plasma membranes isolated from rat liver and hepatoma

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12 December 2020

Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas

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12 December 2020

Tumor progression is associated with a significant decrease in the expression of the endostatin precursor collagen XVIII in human hepatocellular carcinomas

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0001878

Identifiers

DOI

1 reference

ADS bibcode

2008PLoSO...3.1878Q

0 references

1 reference

1 reference

PubMed publication ID

18382662

1 reference