New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases (Q27314812)

25 June 2017

New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases (English)

1 reference

25 June 2017

0 references

1 reference

Sylvain Marchand-Adam

12

Sylvain Marchand-Adam

0 references

Sandrine Dallet-Choisy

Sandrine Dallet-Choisy

5

0 references

Magdalena Wysocka

Magdalena Wysocka

11

0 references

Martine Cadene

Martine Cadene

8

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Antonia Vlahou

Antonia Vlahou

10

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Brice Korkmaz

Brice Korkmaz

16

0 references

Adam Lesner

Adam Lesner

14

0 references

Marcin Sieńczyk

6

Marcin Sieńczyk

1 reference

25 June 2017

2

Monika Legowska

1 reference

25 June 2017

Carla Guarino

1

1 reference

25 June 2017

Christophe Epinette

3

1 reference

25 June 2017

Christine Kellenberger

4

1 reference

25 June 2017

Guillaume Gabant

7

1 reference

25 June 2017

Jérôme Zoidakis

9

1 reference

25 June 2017

Dieter E Jenne

13

1 reference

25 June 2017

Francis Gauthier

15

1 reference

25 June 2017

language of work or name

English

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publication date

6 October 2014

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25 June 2017

15

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Journal of Biological Chemistry

inferred from page(s)

published in

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25 June 2017

289

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25 June 2017

46

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25 June 2017

31777-31791

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Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin

25 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Peptide Length and Leaving-Group Sterics Influence Potency of Peptide Phosphonate Protease Inhibitors

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Discriminating between the activities of human neutrophil elastase and proteinase 3 using serpin-derived fluorogenic substrates

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

On the size of the active site in proteases. I. Papain

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Neutrophil elastase, proteinase 3 and cathepsin G: physicochemical properties, activity and physiopathological functions

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Wegener's autoantigen decoded

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Current understanding of the pathogenesis of granulomatosis with polyangiitis (Wegener's).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Relevance of the mouse model as a therapeutic approach for neutrophil proteinase 3-associated human diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Selective inhibitors of human neutrophil proteinase 3.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Phosphonic esters and their application of protease control

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Profilin 1 is a potential biomarker for bladder cancer aggressiveness

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Molecular analysis of the membrane insertion domain of proteinase 3, the Wegener's autoantigen, in RBL cells: implication for its pathogenic activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Phosphonic pseudopeptides as human neutrophil elastase inhibitors--a combinatorial approach

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Structures of human proteinase 3 and neutrophil elastase--so similar yet so different

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Irreversible inhibition of serine proteases - design and in vivo activity of diaryl alpha-aminophosphonate derivatives

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

A hydrophobic patch on proteinase 3, the target of autoantibodies in Wegener granulomatosis, mediates membrane binding via NB1 receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Pathogenesis of PR3-ANCA associated vasculitis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Computational prediction of the binding site of proteinase 3 to the plasma membrane

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Targeting proteases: successes, failures and future prospects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

EPI-hNE4, a proteolysis-resistant inhibitor of human neutrophil elastase and potential anti-inflammatory drug for treating cystic fibrosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Occurrence of autoantibodies to human leucocyte elastase in Wegener's granulomatosis and other inflammatory disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Elastase-like enzymes in human neutrophils localized by ultrastructural cytochemistry

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Catalytic activity and inhibition of wegener antigen proteinase 3 on the cell surface of human polymorphonuclear neutrophils.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231656

Membrane expression of proteinase 3 is genetically determined

31 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

Measuring elastase, proteinase 3 and cathepsin G activities at the surface of human neutrophils with fluorescence resonance energy transfer substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

Design and use of highly specific substrates of neutrophil elastase and proteinase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

How does proteinase 3 interact with lipid bilayers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

Inhibition of neutrophil elastase by alpha1-protease inhibitor at the surface of human polymorphonuclear neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

Influence of Charge Distribution at the Active Site Surface on the Substrate Specificity of Human Neutrophil Protease 3 and Elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

Differences in the substrate binding sites of murine and human proteinase 3 and neutrophil elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.591339

alpha-Aminoalkylphosphonate di(chlorophenyl) esters as inhibitors of serine proteases

21 January 2018

1 reference

12 December 2020

Bimodal distribution of proteinase 3 (PR3) surface expression reflects a constitutive heterogeneity in the polymorphonuclear neutrophil pool

1 reference

12 December 2020

Presence of proteinase 3 in secretory vesicles: evidence of a novel, highly mobilizable intracellular pool distinct from azurophil granules

1 reference

12 December 2020

Inhibition of trypsin and urokinase by Cbz-amino(4-guanidinophenyl)methanephosphonate aromatic ester derivatives: the influence of the ester group on their biological activity

1 reference

12 December 2020

Mutations in neutrophil elastase causing congenital neutropenia lead to cytoplasmic protein accumulation and induction of the unfolded protein response

1 reference

12 December 2020

A substrate-based approach to convert SerpinB1 into a specific inhibitor of proteinase 3, the Wegener's granulomatosis autoantigen

1 reference

12 December 2020

Proteinase 3, the autoantigen in granulomatosis with polyangiitis, associates with calreticulin on apoptotic neutrophils, impairs macrophage phagocytosis, and promotes inflammation

1 reference

12 December 2020

Irreversible inhibition of serine proteases by peptidyl derivatives of alpha-aminoalkylphosphonate diphenyl esters

1 reference

12 December 2020

Chymase-directed serine protease inhibitor that reacts with a single 30-kDa granzyme and blocks NK-mediated cytotoxicity

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M114.591339

1 reference

25 June 2017

0 references

1 reference