PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes (Q27320965)

8

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Natascha Hermann-Kleiter

3

object named as

Natascha Hermann-Kleiter

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author name string

Katarzyna Wachowicz

2

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Sandra Kaminski

4

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Friedrich Fresser

5

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Christina Lutz-Nicoladoni

6

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Michael Leitges

7

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Ramin Massoumi

9

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Gottfried Baier

Creative Commons Attribution 4.0 International

10

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language of work or name

English

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publication date

2013

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published in

PLOS One

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volume

8

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issue

1

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page(s)

e53709

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copyright license

start time

15 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28

21 March 2017

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CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

21 March 2017

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T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

21 March 2017

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PKCtheta cooperates with atypical PKCzeta and PKCiota in NF-kappaB transactivation of T lymphocytes

21 March 2017

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CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1

21 March 2017

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Phosphorylation of CARMA1 plays a critical role in T Cell receptor-mediated NF-kappaB activation

21 March 2017

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The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 March 2017

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Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

21 March 2017

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CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 March 2017

1 reference

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Identification of the familial cylindromatosis tumour-suppressor gene

21 March 2017

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NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway

21 March 2017

1 reference

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Caspase 8 inhibits programmed necrosis by processing CYLD

21 March 2017

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Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

21 March 2017

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Regulation of T cell development by the deubiquitinating enzyme CYLD

21 March 2017

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Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice

21 March 2017

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Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses

21 March 2017

1 reference

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Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

21 March 2017

1 reference

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Immunodeficiency in protein kinase cbeta-deficient mice

21 March 2017

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T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.

21 March 2017

1 reference

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PKCtheta is necessary for efficient activation of NFkappaB, NFAT, and AP-1 during positive selection of thymocytes

28 September 2017

1 reference

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Protein kinase C-theta is required for efficient positive selection

28 September 2017

1 reference

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Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling

28 September 2017

1 reference

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T-cell fate and function: PKC-theta and beyond

28 September 2017

1 reference

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The proteolytic activity of the paracaspase MALT1 is key in T cell activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Protein kinase C theta (PKCtheta): a key player in T cell life and death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Protein kinase C theta is not essential for T-cell-mediated clearance of murine gammaherpesvirus 68.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Negative regulation of JNK signaling by the tumor suppressor CYLD.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Perspectives on PKCtheta in T cell activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Inside the crawling T cell: leukocyte function-associated antigen-1 cross-linking is associated with microtubule-directed translocation of protein kinase C isoenzymes beta(I) and delta.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546006

Protein kinase Ctheta controls Th1 cells in experimental autoimmune encephalomyelitis.

28 September 2017

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053709

Loss of protein kinase C theta, Bcl10, or Malt1 selectively impairs proliferation and NF-kappa B activation in the CD4+ T cell subset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053709

Protein kinase C beta is dispensable for TCR-signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053709

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053709

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053709

Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23335970

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PKCtheta and PKA are antagonistic partners in the NF-AT transactivation pathway of primary mouse CD3+ T lymphocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23335970